American Airlines Flight 4604 Deals & Information (2026/2027)

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American Airlines Flight 4604 Route Deals From $172

The cheapest prices found with in the last 7 days for return flights were $275 and $172 for one-way flights to LaGuardia for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Sep 10 - Sat, Sep 12
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$275 Roundtrip, found 5 days ago
$275
Roundtrip
found 5 days ago
Select American Airlines flight, departing Thu, Sep 10 from John Glenn Columbus Intl. to LaGuardia, returning Sat, Sep 12, priced at $275 found 5 days ago
Thu, Sep 10 - Sat, Sep 12
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$285 Roundtrip, found 5 days ago
$285
Roundtrip
found 5 days ago
Select American Airlines flight, departing Thu, Sep 10 from John Glenn Columbus Intl. to LaGuardia, returning Sat, Sep 12, priced at $285 found 5 days ago
Tue, Oct 20 - Tue, Oct 27
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$293 Roundtrip, found 2 days ago
$293
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Oct 20 from John Glenn Columbus Intl. to LaGuardia, returning Tue, Oct 27, priced at $293 found 2 days ago
Fri, Sep 11 - Sat, Sep 12
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$295 Roundtrip, found 2 hours ago
$295
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Fri, Sep 11 from John Glenn Columbus Intl. to LaGuardia, returning Sat, Sep 12, priced at $295 found 2 hours ago
Fri, Sep 11 - Sat, Sep 12
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$305 Roundtrip, found 2 hours ago
$305
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Fri, Sep 11 from John Glenn Columbus Intl. to LaGuardia, returning Sat, Sep 12, priced at $305 found 2 hours ago
Sat, Sep 5 - Tue, Sep 8
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$309 Roundtrip, found 4 days ago
$309
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Sep 5 from John Glenn Columbus Intl. to LaGuardia, returning Tue, Sep 8, priced at $309 found 4 days ago
Thu, Oct 29 - Tue, Nov 3
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$323 Roundtrip, found 2 days ago
$323
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Oct 29 from John Glenn Columbus Intl. to LaGuardia, returning Tue, Nov 3, priced at $323 found 2 days ago
Fri, Sep 11 - Sat, Sep 12
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$339 Roundtrip, found 2 hours ago
$339
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Fri, Sep 11 from John Glenn Columbus Intl. to LaGuardia, returning Sat, Sep 12, priced at $339 found 2 hours ago
Fri, Sep 11 - Sat, Sep 12
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$349 Roundtrip, found 2 hours ago
$349
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Fri, Sep 11 from John Glenn Columbus Intl. to LaGuardia, returning Sat, Sep 12, priced at $349 found 2 hours ago
Fri, Sep 11 - Sat, Sep 12
CMH
John Glenn Columbus Intl.
LGA
LaGuardia
$351 Roundtrip, found 2 hours ago
$351
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Fri, Sep 11 from John Glenn Columbus Intl. to LaGuardia, returning Sat, Sep 12, priced at $351 found 2 hours ago

Frequently asked questions

What route does flight number AA4604 take?
AA4604 flies straight between Portland Intl. Jetport Airport (PWM) and O'Hare Airport in about 2 hours and 52 minutes. It can sometimes take other routes though, some of which may be multi-stop trips. Keep this in mind when booking your seat to avoid any confusion.
What kind of plane is on flight number AA4604?
If you're on flight AA4604 from Portland, ME Airport (PWM-Portland Intl. Jetport) to O'Hare Intl. Airport (ORD), you'll likely be jetting off on an Embraer 175. Flight AA4604 serves several routes, but this is the most popular one.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA4604 flight with Travelocity, please visit our Customer Service Portal.