
$253 Cheap American Airlines flights from Medford to Charleston (MFR to CHS)
Find The Best Day To Fly from Medford to Charleston
Amazing American Airlines MFR to CHS Flight Deals
The cheapest flights to Charleston Intl. found within the past 7 days were $468 round trip and $253 one way. Prices and availability subject to change. Additional terms may apply.
CHS From MFR Economy Coach Packages on Similar Airlines



Discover our best American Airlines flight from Medford MFR to Charleston CHS
To find the best deals on flights to Medford from Charleston with American Airlines, just enter your travel dates, filter by American Airlines, and hit search. You’ll find flights to choose from and can sort by price, flight duration, and arrival or departure time.
Return flights from Medford MFR to Charleston CHS with American Airlines
If you’re planning a round trip, booking return flights with American Airlines is usually the most cost-effective option. With airfares ranging from $468 to $468, it’s easy to find a flight that suits your budget. Prices and availability subject to change. Additional terms may apply.
Book one-way American Airlines flights from Medford MFR to Charleston CHS
A one-way ticket gives you much greater flexibility—allowing you to choose your return date, destination, and time whenever you’re ready. By booking in advance you can find great deals on one-way tickets too. Right now, a one-way American Airlines flight from Medford to Charleston costs from $253. Prices and availability subject to change. Additional terms may apply.
The easy way to find cheap flights to Charleston CHS from Medford MFR with American Airlines
To find a cheap American Airlines flight from Medford MFR to Charleston CHS, sort your search results by price or filter by budget. Thanks to Travelocity’s Price Match Promise, if you find a better airfare deal anywhere else within 24 hours, we’ll credit or refund the difference.
How to find our best airfare deals on American Airlines flights from Medford MFR to Charleston CHS
If you’re looking for cheap flights, it helps to be flexible when it comes to your travel dates. You’ll usually find lower cost tickets when you travel during quieter months such as August, or if you book a flight with a stopover.
Find nonstop flights from Medford MFR to Charleston CHS with American Airlines
If you’re keen to be on Charleston soil fast, don’t waste time with a stopover—filter your search results to show direct American Airlines flights only. The journey takes around hour(s) min(s) – so you’ll be there before you know it.
Flexible airline tickets for American Airlines flights from Medford MFR to Charleston CHS
Make sure you’re not out of pocket if plans change by choosing a flexible ticket with penalty-free amendment and cancellation options. Use our ‘no change fee’ filter to see which flights have this option.
There are a lot of reasons to book your flights to Charleston CHS from Medford MFR with American Airlines on Travelocity
At Travelocity our vast and up-to-the-minute inventory puts all of our best flight deals in one place. So, whether you’re traveling on business or jetting off with friends and family, you can trust Travelocity to get you there.
Airport code | Country | Airport name | Number of flights |
---|---|---|---|
DFW | USA | Dallas-Fort Worth Intl. | 599 |
CLT | USA | Charlotte-Douglas Intl. | 536 |
ORD | USA | O'Hare Intl. | 317 |
PHL | USA | Philadelphia Intl. | 247 |
MIA | USA | Miami Intl. | 193 |
DCA | USA | Ronald Reagan Washington National | 152 |
PHX | USA | Sky Harbor Intl. | 141 |
LAX | USA | Los Angeles Intl. | 81 |
LGA | USA | LaGuardia | 72 |
BOS | USA | Logan Intl. | 57 |
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Popular American Airlines Flight Routes from MFR
Top American Airlines Flight Routes from CHS
Domestic
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- Chicago to Orlando (ORD - MCO)
- Philadelphia to Orlando (PHL - MCO)
- New York to San Juan (JFK - SJU)
- New York to Santiago (JFK - STI)
- Chicago to Las Vegas (ORD - LAS)
- Los Angeles to San Salvador (LAX - SAL)
- Chicago to Las Vegas (ORD - LAS)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- Orlando to San Juan (MCO - SJU)
International
- Orlando to San Juan (MCO - SJU)
- Newark Liberty Intl. Airport to Santiago (EWR - STI)
- Atlanta to Las Vegas (ATL - LAS)
- Newark Liberty Intl. Airport to Fort Lauderdale (EWR - FLL)
- Newark Liberty Intl. Airport to Santo Domingo (EWR - SDQ)
- Washington to San Salvador (IAD - SAL)
- Chicago to Mexico City (ORD - MEX)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- Ontario to San Salvador (ONT - SAL)
- Newark Liberty Intl. Airport to Santiago (EWR - STI)
Most Popular
- Portland to Orlando (PDX - MCO)
- Portland to San Diego (PDX - SAN)
- Portland to Chicago (PDX - ORD)
- Portland to Los Angeles (PDX - LAX)
- Portland to Denver (PDX - DEN)
- Boston to Myrtle Beach (BOS - MYR)
- Minneapolis to Portland (MSP - PDX)
- Portland to Salt Lake City (PDX - SLC)
- Hartford to Myrtle Beach (BDL - MYR)
- Las Vegas to Portland (LAS - PDX)
- Orange County to Portland (SNA - PDX)
- Salt Lake City to Portland (SLC - PDX)
- Denver to Portland (DEN - PDX)
- Phoenix to Portland (PHX - PDX)
- Chicago to Portland (ORD - PDX)
- Portland to Orange County (PDX - SNA)
- Los Angeles to Portland (LAX - PDX)
- Portland to Las Vegas (PDX - LAS)
- Portland to New York (PDX - JFK)
- San Francisco to Portland (SFO - PDX)
- Portland to Honolulu (PDX - HNL)
- Portland to Minneapolis (PDX - MSP)
- Portland to Phoenix (PDX - PHX)
- San Diego to Portland (SAN - PDX)
- Greenville to Orlando (GSP - MCO)
- Philadelphia to Myrtle Beach (PHL - MYR)
- Dallas to Portland (DFW - PDX)
- Portland to Dallas (PDX - DFW)
- Portland to San Francisco (PDX - SFO)
- Portland to London (PDX - LHR)