$268 Cheap American Airlines flights from Palm Springs to Knoxville (PSP to TYS)

Find The Best Day To Fly from Palm Springs to Knoxville

Amazing American Airlines PSP to TYS Flight Deals

The cheapest flights to McGhee Tyson found within the past 7 days were $389 round trip and $268 one way. Prices and availability subject to change. Additional terms may apply.

Mon, Oct 6 - Wed, Oct 22
PSP
Palm Springs
TYS
Knoxville
$389 Roundtrip, found 1 day ago
$389
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Oct 6 from Palm Springs to Knoxville, returning Wed, Oct 22, priced at $389 found 1 day ago
Tue, Sep 30 - Wed, Oct 22
PSP
Palm Springs
TYS
Knoxville
$394 Roundtrip, found 1 day ago
$394
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Sep 30 from Palm Springs to Knoxville, returning Wed, Oct 22, priced at $394 found 1 day ago
Wed, Nov 5 - Wed, Nov 26
PSP
Palm Springs
TYS
Knoxville
$414 Roundtrip, found 1 day ago
$414
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Nov 5 from Palm Springs to Knoxville, returning Wed, Nov 26, priced at $414 found 1 day ago
Fri, Aug 1 - Tue, Aug 5
PSP
Palm Springs
TYS
Knoxville
$434 Roundtrip, found 7 hours ago
$434
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Fri, Aug 1 from Palm Springs to Knoxville, returning Tue, Aug 5, priced at $434 found 7 hours ago
Thu, Jul 31 - Fri, Aug 8
PSP
Palm Springs
TYS
Knoxville
$446 Roundtrip, found 7 hours ago
$446
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Thu, Jul 31 from Palm Springs to Knoxville, returning Fri, Aug 8, priced at $446 found 7 hours ago
Tue, Jul 29 - Thu, Aug 7
PSP
Palm Springs
TYS
Knoxville
$449 Roundtrip, found 7 hours ago
$449
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Tue, Jul 29 from Palm Springs to Knoxville, returning Thu, Aug 7, priced at $449 found 7 hours ago

TYS From PSP Economy Coach Packages on Similar Airlines

Price found within the past 48 hours. Click for updated prices.
Hampton Inn Gatlinburg Historic Nature Trail

Hampton Inn Gatlinburg Historic Nature Trail

2.5 out of 5
per person
Oct 8 - Oct 12
found 14 hours ago
Roundtrip non-stop flight included
Ontario (ONT) to Knoxville (TYS)
Westgate Smoky Mountain Resort & Water Park

Westgate Smoky Mountain Resort & Water Park

4 out of 5
Save 100% on your flight
per person
Oct 8 - Oct 12
found 14 hours ago
Roundtrip non-stop flight included
Ontario (ONT) to Knoxville (TYS)
Courtyard by Marriott Gatlinburg Downtown

Courtyard by Marriott Gatlinburg Downtown

3 out of 5
Save 100% on your flight
per person
Oct 8 - Oct 12
found 14 hours ago
Roundtrip non-stop flight included
Ontario (ONT) to Knoxville (TYS)
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American Airlines Airports
Hop on a(n) American Airlines flight today by flying to many destinations out of these domestic and international airports:
Airport code
Country
Airport name
Number of flights
DFWUSADallas-Fort Worth Intl.599
CLTUSACharlotte-Douglas Intl.536
ORDUSAO'Hare Intl.317
PHLUSAPhiladelphia Intl.247
MIAUSAMiami Intl.193
DCAUSARonald Reagan Washington National152
PHXUSASky Harbor Intl.141
LAXUSALos Angeles Intl.81
LGAUSALaGuardia72
BOSUSALogan Intl.57

Travelers ❤️ these 🏨 after their flight to Knoxville

Hilton Knoxville Airport

Hilton Knoxville Airport

3.5 out of 5
2001 Alcoa Hwy, Alcoa, TN
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9/10 Wonderful! (1,011 reviews)
"Great location to the airport and fantastic staff!"

Reviewed on Jul 15, 2025

Hilton Knoxville Airport
La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road, Alcoa, TN
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free ...
8.6/10 Excellent! (1,477 reviews)
"Exactly what we needed for our business trip. Highly recommended ⭐️⭐️⭐️⭐️⭐️"

Reviewed on Jul 14, 2025

La Quinta Inn & Suites by Wyndham Knoxville Airport
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd, Alcoa, TN
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport ...
8.4/10 Very Good! (1,014 reviews)
"Very clean"

Reviewed on Jul 16, 2025

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.