Find a Hotel in Uptown

Start date: Check-in selected.
To Date
End date: Check-out

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top hotels in Uptown

Rhett House Inn

Rhett House Inn

4 out of 5
1009 Craven St Beaufort SC
$152 nightly
The price is $167 total per night from Jan 7 to Jan 8
$167 total
Jan 7 - Jan 8
Total with taxes and fees
A restaurant and a bar/lounge are featured at this bed & breakfast. Traveling on business? Take advantage of the free WiFi in public areas and free internet ...
Amenities

Reviewed on Dec 11, 2025

Opens in a new windowRhett House Inn
Tru by Hilton Beaufort, SC

Tru by Hilton Beaufort, SC

2.5 out of 5
3662 Trask Parkway Beaufort SC
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $108 total per night from Jan 6 to Jan 7
$108 total
Jan 6 - Jan 7
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...
Great staff, clean room, fresh coffee at 8pm.

Reviewed on Jan 1, 2026

Opens in a new windowTru by Hilton Beaufort, SC
Hilton Garden Inn Hilton Head

Hilton Garden Inn Hilton Head

3 out of 5
1575 Fording Island Rd Hilton Head Island SC
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $105 total per night from Jan 11 to Jan 12
$105 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Relax with a drink at the bar/lounge and enjoy perks like free self parking and free WiFi. A business ...
Staff were professional, upbeat & helpful. Room was clean & comfortable. Hotel was well located with plenty of parking & nearby food options.

Reviewed on Dec 24, 2025

Opens in a new windowHilton Garden Inn Hilton Head
The Westin Hilton Head Island Resort & Spa

The Westin Hilton Head Island Resort & Spa

4 out of 5
2 Grasslawn Ave Hilton Head Island SC
Fully refundableReserve now, pay when you stay
$168 nightly
The price is $185 total per night from Jan 26 to Jan 27
$185 total
Jan 26 - Jan 27
Total with taxes and fees
This smoke-free hotel features a golf course, a full-service spa, and 2 restaurants. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. ...
What a great location and the resort is one of the best resort i stayed in southern states

Reviewed on Dec 27, 2025

Opens in a new windowThe Westin Hilton Head Island Resort & Spa
Hampton Inn Hilton Head

Hampton Inn Hilton Head

2.5 out of 5
1 Dillon Road Hilton Head Island SC
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $103 total per night from Jan 25 to Jan 26
$103 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 2 conference rooms, free WiFi in public areas, and express check-in. ...
Yes and yes

Reviewed on Dec 30, 2025

Opens in a new windowHampton Inn Hilton Head
Spark by Hilton Bluffton Hilton Head Island

Spark by Hilton Bluffton Hilton Head Island

2.5 out of 5
23 Towne Dr Bluffton SC
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $89 total per night from Jan 11 to Jan 12
$89 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Relaxing overnight stay. Room spacious, clean, quiet. Adequate breakfast to send you on your way. Highly recommend

Reviewed on Jan 2, 2026

Opens in a new windowSpark by Hilton Bluffton Hilton Head Island
Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG

Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG

3 out of 5
2225 Boundary St Beaufort SC
Fully refundable
$93 nightly
The price is $102 total per night from Jan 11 to Jan 12
$102 total
Jan 11 - Jan 12
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Beautiful hotel, love the breakfast, wonderful staff

Reviewed on Dec 22, 2025

Opens in a new windowHoliday Inn Hotel & Suites Beaufort at Highway 21 by IHG
Extended Stay America Premier Suites Bluffton Hilton Head

Extended Stay America Premier Suites Bluffton Hilton Head

2.5 out of 5
108 Seagrass Station Road Bluffton SC
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $89 total per night from Jan 5 to Jan 6
$89 total
Jan 5 - Jan 6
Total with taxes and fees
A 24-hour gym, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like on-the-go breakfast and WiFi in public ...
Excellent staff (Aesha & Miai) have made my stay very positive. Clean room and amenities make it less stressful. Highly recommend!

Reviewed on Dec 31, 2025

Opens in a new windowExtended Stay America Premier Suites Bluffton Hilton Head
Best Western Point South

Best Western Point South

2.5 out of 5
3536 Point South Drive Yemassee SC
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $101 total per night from Jan 5 to Jan 6
$101 total
Jan 5 - Jan 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the 24-hour business ...
Best tv ever!!!!!!

Reviewed on Dec 31, 2025

Opens in a new windowBest Western Point South
Don't see what you're looking for?
See all available properties in Uptown
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Uptown Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Uptown area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Uptown to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Uptown are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Uptown hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity