Book Hotels in Southeast Iowa
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Check prices for these dates
Top Southeast Iowa hotels
Cobblestone Inn & Suites - Fort Madison
4901 Avenue O Fort Madison IA
Fully refundable
$75 nightly
The price is $84 total per night from Dec 7 to Dec 8
$84 total
Dec 7 - Dec 8
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...
One of the nicer stays we have experienced. Great clean room and breakfast. Helpful staff.
Reviewed on Nov 27, 2025
Nauvoo Temple House Hotel
1200 Mulholland St Nauvoo IL
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $98 total per night from Jan 3 to Jan 4
$98 total
Jan 3 - Jan 4, 2026
Total with taxes and fees
Free WiFi in public areas is available at this hotel. Take advantage of the free self parking.
Very convenient walk to the Nauvoo temple. It's an old area but very nice. The only downside was the old hotel didn't have an elevator.
Reviewed on Nov 29, 2025
Comfort Suites Burlington
1780 Stonegate Center Dr Burlington IA
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $124 total per night from Dec 21 to Dec 22
$124 total
Dec 21 - Dec 22
Total with taxes and fees
This hotel features an indoor pool and a gym. Enjoy the hot tub and free perks like buffet breakfast and free self parking. A 24-hour business center, free WiFi ...
It was not spotless there were
Reviewed on Nov 29, 2025
AmericInn by Wyndham Mount Pleasant
1100 N Grand Ave Mount Pleasant IA
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $85 total per night from Dec 7 to Dec 8
$85 total
Dec 7 - Dec 8
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Clean rooms and courteous staff.
Reviewed on Nov 29, 2025
Quality Inn & Suites Keokuk North
3404 Main St Keokuk IA
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $90 total per night from Dec 28 to Dec 29
$90 total
Dec 28 - Dec 29
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
Very clean, staff were very nice. Easy to get to. Big room. Comfy couch and bed. Good value. Would stay here again.
Reviewed on Oct 24, 2025
Fun City Resort Hotel
3001 Winegard Drive Burlington IA
Fully refundableReserve now, pay when you stay
$168 nightly
The price is $188 total per night from Dec 6 to Dec 7
$188 total
Dec 6 - Dec 7
Total with taxes and fees
This Art Deco hotel features a casino, a water park, and a restaurant. Bring the family and enjoy the lazy river, free kid's club, and kid-friendly dining. Enjoy ...
Room was great!
Reviewed on Nov 4, 2025
Best Western Mt. Pleasant Inn
810 N Grand Avenue Mount Pleasant IA
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $81 total per night from Dec 11 to Dec 12
$81 total
Dec 11 - Dec 12
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Relax with ...
Clean room Friendly staff easy check in
Reviewed on Nov 14, 2025
AmericInn by Wyndham West Burlington
628 S Gear Ave West Burlington IA
Fully refundableReserve now, pay when you stay
$56 nightly
The price is $63 total per night from Jan 4 to Jan 5
$63 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Families will appreciate the arcade/game ...
Very nice room, staff great.
Reviewed on Dec 2, 2025
Baymont by Wyndham Keokuk
325 Main St Keokuk IA
Fully refundableReserve now, pay when you stay
$50 nightly
The price is $56 total per night from Jan 4 to Jan 5
$56 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
An indoor pool is featured at this hotel, along with free self parking. Guests will appreciate free perks like on-the-go breakfast and WiFi in public areas. ...
Clean room, Great staff, Great amenities.
Reviewed on Nov 26, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southeast Iowa hotels
Baymont by Wyndham Keokuk
325 Main St Keokuk IA
$50 nightly
The price is $56 total per night from Jan 4 to Jan 5
$56 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
6.2/10 (488 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southeast Iowa with star-rating
Check Southeast Iowa Hotels by Star Rating
4 Star Hotels
1 properties
Recent Southeast Iowa hotel reviews by fellow wanderers
Hampton Inn Keokuk
5 out of 5
Posted 5 days ago
Travelocity Verified Review
"The staff was friendly and informative, during a winter storm they were genuinely concerned that we would be travelling and wished us well. The breakfast was great! Something for each member of a family of 5. It will become our "go to" for stops in the area for sure."
A verified traveler stayed at Hampton Inn Keokuk
Explore More Ways to Travel with Travelocity
- Farmstay in Central United States
- Condo Resorts in Central United States
- Guest Houses in Central United States
- All Inclusive Resorts & in Central United States
- Beach Resorts & in Central United States
- Benchmark Hotels in Central United States
- Citizenm Hotels in Central United States
- Drury Inn & Suites Hotels in Central United States
- Four Seasons Hotels in Central United States
- Hilton Hotels in Central United States
- Hotels with Early Check-in in Central United States
- Hotels with Waterslides in Central United States
- Hyatt Hotels in Central United States
- Loews Hotels in Central United States
- Remington Hotels in Central United States
- Ski Resorts and in Central United States
- Sonesta Hotel in Central United States
- Spa Resorts & in Central United States
- Wyndham Hotels in Central United States
- Central United States Hotels
- Rv Parks in Central United States
- Hotels near Mississippi River
- 4 Star Hotels in Quad Cities
- 5 Star Hotels in Quad Cities
- Apartments in Quad Cities
- B&B in Quad Cities
- Cabins in Quad Cities
- Cottages in Quad Cities
- Extended Stay Hotels in Quad Cities
- Arcade Hotels in Quad Cities
- Boutique Hotels in Quad Cities
- Casino Resorts & in Quad Cities
- Cheap Hotels in Quad Cities
- Kid Friendly Hotels in Quad Cities
- Gay Friendly Hotels in Quad Cities
- Golf Resorts & in Quad Cities
- Historic Hotels in Quad Cities
- Hotels with Early Check-in in Quad Cities
- Hotels with Pools in Quad Cities
- Hotels with Bar in Quad Cities
- Hotels with Free Parking in Quad Cities
- Hotels with Hot Tubs in Quad Cities
- Hotels with an Indoor Pool in Quad Cities
- Hotels with Kitchenettes in Quad Cities
- Hotels with smoking rooms in Quad Cities
- Luxury Hotels in Quad Cities
- Pet Friendly Hotels in Quad Cities
- Hotels on the River in Quad Cities
- Romantic Getaways & Hotels in Quad Cities
- Spa Resorts & in Quad Cities
- Waterpark Hotels and Resorts in Quad Cities
- Quad Cities Hotels
- Houseboats in Quad Cities
- Motels in Quad Cities
- Vacation Homes in Quad Cities
- Rv Parks in Quad Cities
- Flights to Central United States
- Flights from Miami to Central United States
- Flights to Quad Cities
- Flights from Kitchener to Quad Cities
- Flights from Atlanta to Quad Cities
- Flights from Boston to Quad Cities
- Flights from Brussels to Quad Cities
- Flights from Calgary to Quad Cities
- Flights from Dallas to Quad Cities
- Flights from Indianapolis to Quad Cities
- Flights from Las Vegas to Quad Cities
- Flights from Minneapolis - St. Paul to Quad Cities
- Flights from Montreal to Quad Cities
- Flights from Nashville to Quad Cities
- Flights from New Orleans to Quad Cities
- Flights from St. Louis to Quad Cities
- Flights from Toronto to Quad Cities
- Flights from Barcelona to Quad Cities
- Flights from Providence to Quad Cities
- Flights from Muskrat Dam to Quad Cities
- Flights from Fort Lauderdale to Quad Cities
- Flights from Atlantic City to Quad Cities
- Flights from Tulsa to Quad Cities
- Flights from Scranton to Quad Cities
- Flights from Albuquerque to Quad Cities
- Flights from Spokane to Quad Cities
- Flights from Lincoln to Quad Cities
- Flights from Huntsville to Quad Cities
- Flights from Tucson to Quad Cities
- Flights from Boise to Quad Cities
- Flights from Wichita to Quad Cities
