Book Hotels in Santa Cruz

Start date: Check-in selected.
To Date
End date: Check-out

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Tonight
Nov 11 - Nov 12
Tomorrow
Nov 12 - Nov 13
This weekend
Nov 14 - Nov 16
Next weekend
Nov 21 - Nov 23

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top Santa Cruz hotels

York Luxury Suites Medellín

York Luxury Suites Medellín

4 out of 5
Carrera 43a 17sur 63, Medellín, Antioquia
Fully refundableReserve now, pay when you stay
$165 nightly
The price is $165 total per night from Dec 1 to Dec 2
$165 total
Dec 1 - Dec 2
This aparthotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
Second time staying at York and it never disappoints! Great views, central and safe, staff is always friendly and willing to help. Staff came and cleaned the room daily. Great hotel definitely recommend.

Reviewed on Nov 10, 2025

Opens in a new windowYork Luxury Suites Medellín
Novotel Medellín El Tesoro

Novotel Medellín El Tesoro

4.5 out of 5
Cra 25a # 1 a sur 45, Medellín, Antioquia
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $135 total per night from Nov 16 to Nov 17
$135 total
Nov 16 - Nov 17
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Traveling on business? Take advantage of the free WiFi in public ...
Everyone in the hotel was absolutely incredible. I enjoyed every second. I think my only vice was the floors not being totally clean (hair, a bit of dirt which showed up on my cream bunny slippers). However, the kindness of the staff more than made up for it. Breakfast each morning was wonderful. ...

Reviewed on Nov 3, 2025

Opens in a new windowNovotel Medellín El Tesoro
Hotel Park 10

Hotel Park 10

4 out of 5
Carrera 36b No.11-12, Medellín, Antioquia
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $88 total per night from Nov 20 to Nov 21
$88 total
Nov 20 - Nov 21
This smoke-free hotel features a full-service spa, 2 hot tubs, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public ...
Room was clean, breakfast was excellent

Reviewed on Nov 8, 2025

Opens in a new windowHotel Park 10
Heiss Hotel By Jalo

Heiss Hotel By Jalo

4 out of 5
1460 Cra. 43F, Medellín, Antioquia
$89 nightly
The price is $89 total per night from Dec 1 to Dec 2
$89 total
Dec 1 - Dec 2
This hotel features an outdoor pool and a gym. Relax with a drink at the poolside bar and enjoy perks like free WiFi. A garden is provided and the front desk ...
Love it

Reviewed on Nov 8, 2025

Opens in a new windowHeiss Hotel By Jalo
Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo

3.5 out of 5
# 37-40 Calle 9A, Medellín
Fully refundableReserve now, pay when you stay
$61 nightly
The price is $61 total per night from Dec 3 to Dec 4
$61 total
Dec 3 - Dec 4
This hotel features 2 restaurants and a bar/lounge. WiFi in public areas is free. Dry cleaning and luggage storage are also provided.
Todo perfecto.

Reviewed on Nov 9, 2025

Opens in a new windowCalle Flora Hotel by Jalo
NH Collection Medellín Royal

NH Collection Medellín Royal

5 out of 5
Carrera 42 No 5 Sur 130, El Poblado, Medellín, Antioquia
$82 nightly
The price is $82 total per night from Nov 30 to Dec 1
$82 total
Nov 30 - Dec 1
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
Great place recommend

Reviewed on Nov 4, 2025

Opens in a new windowNH Collection Medellín Royal
Blues Suites Medellin

Blues Suites Medellin

4 out of 5
Cra 29C #1a sur 80, Medellín, Antioquia
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $108 total per night from Nov 17 to Nov 18
$108 total
Nov 17 - Nov 18
A full-service spa and a restaurant are featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public areas and airport ...
El unico detalle que no me gusto es que enseña en las fotos un Jacuzzi en top y eso lo ELIMANARON. Deberian remover la foto para no crear confusión.

Reviewed on Nov 6, 2025

Opens in a new windowBlues Suites Medellin
Dann Carlton Medellin Hotel

Dann Carlton Medellin Hotel

4.5 out of 5
Carrera 43a No.7-50, Avenida El Poblado, Medellín, Antioquia
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $81 total per night from Dec 8 to Dec 9
$81 total
Dec 8 - Dec 9
A full-service spa, 4 restaurants, and an outdoor pool are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...
Llevo viajando a medellin por los ultimos 6 años y mi hotel preferido es dann carlton . Todo excelente el servicio los empleados la comida gurmet en fin todo es a otro nivel .

Reviewed on Nov 9, 2025

Opens in a new windowDann Carlton Medellin Hotel
Hotel Dorado La 70

Hotel Dorado La 70

4 out of 5
Carrera 70 No 44 B-66, Laureles, Medellín
Fully refundableReserve now, pay when you stay
This traditional hotel features a casino, a nightclub, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in ...
Yes very great

Reviewed on Nov 3, 2025

Get rates
Opens in a new windowHotel Dorado La 70
Don't see what you're looking for?
See all available properties in Santa Cruz
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Santa Cruz?
Family getaways are where you make the best memories, but it's no secret that traveling with little ones can be demanding. These kid-friendly Santa Cruz hotels come with perks that aim to keep young and old alike comfortable and happy: Settle in at Casa Grande Medellin Comuna 1. It comes with a king bed, pet-friendly facilities and a talent for making families feel welcome. Apartment is another great choice. After a big day of exploring, come home to your comfy room and amenities like pet-friendly facilities and internet access.
Where can I find cheap hotels in Santa Cruz?
At Travelocity you'll find really nice hotels in Santa Cruz at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Santa Cruz rather than in Santa Cruz. We may find you even better rates, too.
How do I find the best Santa Cruz hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Santa Cruz then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Santa Cruz?
The cheapest hotel in Santa Cruz is $61. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Santa Cruz?
There are 4,373 hotels in Santa Cruz on Travelocity.
What are the best hotels in Santa Cruz?
Santa Cruz has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Santa Cruz for you!
When is the best time to visit Santa Cruz?
If you want the joy of a fun-filled trip in peak season, visit Santa Cruz during March, May and August. If you'd prefer the peace of off-season, book a stay during quieter months, such as September, November and December.
When is the cheapest time to stay in Santa Cruz?
Based on historic data is usually the cheapest month to visit Santa Cruz. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Santa Cruz?
There are multiple hotels in Santa Cruz that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Santa Cruz. We have plenty of kid-friendly hotels in Santa Cruz to choose from on Travelocity!
Why book a hotel in Santa Cruz through Travelocity?
Because we have the top hotels in Santa Cruz! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Santa Cruz on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Santa Cruz hotel reviews by fellow wanderers

York Luxury Suites Medellín

York Luxury Suites Medellín

5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Second time staying at York and it never disappoints! Great views, central and safe, staff is always friendly and willing to help. Staff came and cleaned the room daily. Great hotel definitely recommend. "
A verified traveler stayed at York Luxury Suites Medellín
York Luxury Suites Medellín

Explore More Ways to Travel with Travelocity