O Brien Vacation Packages 2026 from $706

O Brien flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

Equus Inn Ocala

$706

per person

Nov 1 - Nov 7

found 1 day ago

Roundtrip flight included

Miami (MIA) to Gainesville (GNV)

This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Relax with a drink at the bar/lounge and enjoy free perks like buffet breakfast and free self parking.

Landing Apartments Northwest Ocala

$966

per person

Nov 1 - Nov 7

found 1 day ago

Roundtrip flight included

Miami (MIA) to Gainesville (GNV)

This apartment features an outdoor pool and a 24-hour gym. Guests will appreciate free perks like free self parking and WiFi in public areas. A virtual front desk are provided for your convenience.

Hilton Ocala

$977

per person

Nov 1 - Nov 7

found 1 day ago

Roundtrip flight included

Miami (MIA) to Gainesville (GNV)

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and airport shuttle. You'll appreciate the 24-hour gym, poolside bar, and convenience store.

Top O Brien hotels deals

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!

obrien FL

Get rates

A gym is featured at this vacation home, along with a garden and laundry facilities. There's fun for all ages with a playground and an arcade/game room, and barbecue grills are available on site.

Kitchen

Washer

MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY

O'Brien FL

Get rates

A garden, express check-in, and express check-out are available at this vacation home. Laundry facilities and barbecue grills are also provided.

Kitchen

Washer

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

16367 NW 167TH BLVD Alachua FL

Free Cancellation

$104 nightly

$117 total

Sep 21 - Sep 22

Total with taxes and fees

This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and free perks like buffet breakfast and free self parking.

Pool

Hot Tub

La Quinta Inn & Suite by Wyndham Lake City

165NW CALI DRIVE Lake City FL

Free Cancellation

Reserve now, pay when you stay

$90 nightly

$101 total

Sep 9 - Sep 10

Total with taxes and fees

This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like on-the-go breakfast and free self parking.

Pool

Breakfast included

Best Western Plus Lake City

350 SW Florida Gateway Dr Lake City FL

Free Cancellation

Reserve now, pay when you stay

$81 nightly

$91 total

Sep 10 - Sep 11

Total with taxes and fees

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.

Pool

Breakfast included

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

1699 NE Co Rd 337 High Springs FL

$198 nightly

$218 total

Sep 22 - Sep 23

Total with taxes and fees

This cabin features a virtual front desk. If you want to take your pet along, this pet-friendly property offers everything you'll need for your pet including food and water bowls. Take advantage of the free self parking.

Kitchen

Pet friendly

Don't see what you're looking for?

See all available properties in O Brien

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much are vacation packages to O Brien?

$706 is all you need to spend for a memorable vacation in O Brien. Bundle your flights and hotel into a vacation package with Travelocity and see the savings add up. With prices this good, you'll want to start packing your suitcase now!

How long should my O Brien vacation be?

Many travelers choose to spend about 5 nights in O Brien. But that's only a guide. Whether you prefer to stay for a couple of days or a couple of weeks, you'll love exploring all the amazing things that this destination has to offer.

Where can I get the best vacation package deals for O Brien?

You'll come across an amazing range of O Brien package deals on Travelocity. With 400 airlines and 1,000,000 properties across the globe, organizing your dream vacation will be easy.

Why should I purchase my O Brien vacation package with Travelocity?

Because life is all about the journey, and we have everything you need to help you on your way. With our excellent service and Price Match Guarantee, you can organize your trip with confidence. What's more, you can rest easy on the road knowing you can reach us with our round-the-clock support.

Can I save on my O Brien car rental if I combine it with my hotel or flight?

With an O Brien vacation package, you can combine your hotel, flight and car bookings and save a ton. If you're in the mood to discover the best of this fantastic region, why not start with University of Florida? This renowned attraction is 45 mi from O Brien. With your own rental car, you'll be there in no time.

Which airport is best for O Brien?

One of your top options is Gainesville Regional Airport (GNV), which you'll find 45 mi southeast of downtown O Brien. Your other choice is Valdosta Regional Airport (VLD), 55 mi away from central O Brien).

Where should I stay when visiting O Brien?

Many people opt to check in to the Pet-Friendly Florida Escape w/ Patio & Fire Pit!. It's a terrific base for your O Brien getaway.