Book Hotels in Mill Creek, IL

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Top Mill Creek hotels

Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest

Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest

Jonesboro IL
A hot tub is featured at this cabin, along with a garden and barbecue grills.
Great place for a weekend getaway!

Reviewed on Feb 3, 2026

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Opens in a new windowCabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $109 total per night from Feb 19 to Feb 20
$109 total
Feb 19 - Feb 20
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
The room was great. The facility was excellent. The people were excellent. Definitely going back.

Reviewed on Feb 5, 2026

Opens in a new windowDrury Plaza Hotel Cape Girardeau Conference Center
The Riverview

The Riverview

4 out of 5
777 Main St Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $117 total per night from Feb 17 to Feb 18
$117 total
Feb 17 - Feb 18
Total with taxes and fees
This hotel features a casino and 2 restaurants. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference space. ...
room was great, clean!!

Reviewed on Feb 10, 2026

Opens in a new windowThe Riverview
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
3303 Campster Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Feb 17 to Feb 18
$102 total
Feb 17 - Feb 18
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Everything about this place is great! Highly recommend-you wouldn’t be disappointed

Reviewed on Feb 7, 2026

Opens in a new windowDrury Inn & Suites Cape Girardeau
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

3 out of 5
400 Broadway St. Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $142 total per night from Feb 22 to Feb 23
$142 total
Feb 22 - Feb 23
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Convenient location, clean room, and easy check in/out process. Really cool little downtown.

Reviewed on Feb 1, 2026

Opens in a new windowCourtyard by Marriott Cape Girardeau Downtown
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 out of 5
3253 William Street Cape Girardeau MO
Fully refundable
$95 nightly
The price is $107 total per night from Feb 22 to Feb 23
$107 total
Feb 22 - Feb 23
Total with taxes and fees
A full-service spa and an indoor pool are featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public ...
Would have been a 5 rating except for the noisy heating system.

Reviewed on Feb 2, 2026

Opens in a new windowHoliday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $81 total per night from Feb 17 to Feb 18
$81 total
Feb 17 - Feb 18
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...
Great

Reviewed on Feb 6, 2026

Opens in a new windowPear Tree Inn Cape Girardeau West
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

2.5 out of 5
485 S Mount Auburn Rd Cape Girardeau MO
Fully refundable
$80 nightly
The price is $96 total per night from Feb 22 to Feb 23
$96 total
Feb 22 - Feb 23
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Free self parking, ...
The room itsself was exceptional. Everything was spotless and the beds are very comfortable. However, it was extremely noisy!! The arcade on the 4th floor kept kids running up and down the halls. I thought it strange that housekeeping will not bring towels to your room when requested, instead you ...

Reviewed on Jan 24, 2026

Opens in a new windowCandlewood Suites Cape Girardeau by IHG
Quality Inn

Quality Inn

2.5 out of 5
2011 North Kingshighway Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$58 nightly
The price is $65 total per night from Feb 19 to Feb 20
$65 total
Feb 19 - Feb 20
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like English breakfast and WiFi in public ...
The lady at the front desk was an amazing person and treated me with the upmost respect

Reviewed on Jan 28, 2026

Opens in a new windowQuality Inn
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Mill Creek?
Settle in at Beautiful newly renovated farm house overlooking 5 acre lake. New Rates * and make traveling with your young ones child's play. This popular pick in Mill Creek features amenities designed to make family adventures easier, such as a playground.
Where can I find cheap hotels in Mill Creek?
At Travelocity you'll find really nice hotels in Mill Creek at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Mill Creek rather than in Mill Creek. We may find you even better rates, too.
How do I find the best Mill Creek hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Mill Creek then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Mill Creek?
The cheapest hotel in Mill Creek is $65. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Mill Creek?
There are 157 hotels in Mill Creek on Travelocity.
What are the best hotels in Mill Creek?
Mill Creek has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Mill Creek for you!
When is the best time to visit Mill Creek?
If you want the joy of a fun-filled trip in peak season, visit Mill Creek during June, September and November. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, April and May.
When is the cheapest time to stay in Mill Creek?
Based on historic data is usually the cheapest month to visit Mill Creek. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Mill Creek?
There are multiple hotels in Mill Creek that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Mill Creek. We have plenty of kid-friendly hotels in Mill Creek to choose from on Travelocity!
Why book a hotel in Mill Creek through Travelocity?
Because we have the top hotels in Mill Creek! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Mill Creek on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Mill Creek hotel reviews by fellow wanderers

The Riverview

The Riverview

5 out of 5
Posted 3 days ago
Travelocity Verified Review
"room was great, clean!!"
A verified traveler stayed at The Riverview
The Riverview