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Top Cairo hotels

Charming cottage overlooking Lake Acre

Charming cottage overlooking Lake Acre

Dongola IL
The price is $281 total per night from Jun 7 to Jun 8
$281 total
per night
Jun 7 - Jun 8
This cabin features a garden, laundry facilities, and barbecue grills.
"Such a beautiful and peaceful place to stay Suzzie is a great host I stay there once or twice a year for the past several years loved every minute can’t wait to go back"

Reviewed on Jun 2, 2026

Opens in a new windowCharming cottage overlooking Lake Acre
Wandering the wineries or hitting the hills? We got you! Come stay!

Wandering the wineries or hitting the hills? We got you! Come stay!

Tamms IL
This vacation home features a garden, laundry facilities, and barbecue grills.
"We came to Cape Girardeau for graduation and stayed here for the weekend. The beds were comfy, the outdoor space was lovely and the kitchen was spacious. They have a dart board, plenty of games and movies and have a pool table you can actually use because it’s not crammed in a corner! The hosts are ..."

Reviewed on May 11, 2026

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Opens in a new windowWandering the wineries or hitting the hills? We got you! Come stay!
Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286

Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286

Kevil KY
This vacation home features a garden, laundry facilities, and barbecue grills.
"It was a great place to stay. It’s very easy to get to Paducah and other sites from the house. The host is so great to communicate with. We had to change a day due to my husband interviewing at a church unexpectedly and she was quick to fix it for us. They also provided farm fresh eggs, which we ..."

Reviewed on May 25, 2026

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Opens in a new windowQuiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286
Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake

Olive Branch IL
The price is $140 total per night from Jun 7 to Jun 8
$140 total
per night
Jun 7 - Jun 8
Stay at this cabin in Alexander County. Enjoy patios, an in-room coffeemaker, and air conditioning.
"Beautiful Property"

Reviewed on May 28, 2026

Opens in a new windowCozy cabins on beautiful Horseshoe Lake
La Center Motel

La Center Motel

2 out of 5
474 W Kentucky Dr La Center KY
Fully refundableReserve now, pay when you stay
The price is $70 total per night from Jun 7 to Jun 8
$70 total
per night
Jun 7 - Jun 8
Free WiFi in public areas is available at this hotel. Take advantage of the free self parking.
"This property is very old & not updated. Our room was very stale smelling & I was concerned about the cleanness of the room. Nothing present in tub for handicapped or older people. The guy at the front desk was not friendly at all & was truly alarmingly strange acting. We were concerned. Only good ..."

Reviewed on May 25, 2026

Opens in a new windowLa Center Motel
The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston

2.5 out of 5
102 Drake St Charleston MO
Fully refundableReserve now, pay when you stay
The price is $83 total per night from Jun 7 to Jun 8
$83 total
per night
Jun 7 - Jun 8
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the 24-hour ...
"They cha rged me twice. They promised a refund but I have not seen it yet. Windows was taped up so I could not see out. Room smelled bad. I was also unhappy with the Expedia app."

Reviewed on Jun 1, 2026

Opens in a new windowThe Riverstone Hotel Charleston-Sikeston
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

2 out of 5
310 S Story St Charleston MO
Fully refundableReserve now, pay when you stay
The price is $66 total per night from Jun 14 to Jun 15
$66 total
per night
Jun 14 - Jun 15
This motel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free on-the-go breakfast each morning. There's a computer ...
"Clean rooms,"

Reviewed on May 31, 2026

Opens in a new windowSuper 8 by Wyndham Charleston/Sikeston East MO
Quality Inn Cairo I-57

Quality Inn Cairo I-57

2.5 out of 5
13201 Kessler Road Cairo IL
Fully refundable
The price is $77 total per night from Jun 13 to Jun 14
$77 total
per night
Jun 13 - Jun 14
This hotel features free WiFi in public areas, free newspapers, and free self parking. Enjoy the free full breakfast each morning. A picnic area is provided ...
Opens in a new windowQuality Inn Cairo I-57
Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake

Miller City IL
The price is $185 total per night from Jun 7 to Jun 8
$185 total
per night
Jun 7 - Jun 8
This cabin features barbecue grills.
Opens in a new windowPeaceful secluded cabin located near Horseshoe Lake
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Cairo hotels

Quality Inn Cairo I-57

Quality Inn Cairo I-57

13201 Kessler Road Cairo IL
$70 nightly
The price is $77 total per night from Jun 13 to Jun 14
$77 total
Jun 13 - Jun 14
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cairo Hotel & Travel Guide\n

Travelocity customers dreaming about roaming in Cairo, should think about pre-booking a room as early as possible, as you won't find an abundance of room options in the vicinity of Cairo's center.

A fantastic choice for the times you want to stay within a short walk of the urban core of Cairo, is the Quality Inn.

The Quality Inn Charleston can be found about 12 miles (20 kilometers) from the town center of Cairo. Another hotel is the Super 8 Charleston MO, which is approximately 11 miles (17 kilometers) away. You might like to investigate the Americas Best Value Inn or the Quality Inn.

Once you've found the secrets of Cairo, how about you tour a little more of the area? The Southern Illinois vicinity is home to a number of great other cultural and scenic delights to offer. If you love nature, be sure to explore Southern Illinois's rural landscapes, rolling hills and prairies. In addition you could visit many of its farms. Wise travelers in this corner of United States of America often enjoy rock climbing, hiking and abseiling.

Metropolis is 30 miles (47 kilometers) to the east of Cairo and is where you'll find Super Museum and Americana Hollywood Museum. The Holiday Inn Express Metropolis and Super 8 Metropolis are a few of the great short and long-stay alternatives in Metropolis. 45 miles (76 kilometers) to the north of Cairo, you'll also find Marion, home to the Fairfield Inn and Suites by Marriott Marion and Comfort Suites Marion. Regardless of whether you're passing through or spending a few nights in Marion, be sure to check out the Kokopelli Golf Club and Marion Carnegie Library.

Just because you're taking a break from your usual habits, who's to say that you shouldn't expand your obsession with a day watching sports. Find Rent One Park 50 miles (81 kilometers) to the north of Cairo. Sports fans that hope to find a bed close to the action can select from the Holiday Inn Express Hotel & Suites Marion Northeast or the Comfort Inn Marion.

Cairo attracts visitors with some fantastic things to look at; learn more via our complete Cairo accommodation and attractions guide.

Frequently asked questions

What are the top kid-friendly hotels in Cairo?
Family vacations are where the best memories are made, but it's no secret that traveling with young ones can be challenging. These kid-friendly Cairo hotels come with perks that aim to keep old and young alike relaxed and happy: Quality Inn Cairo I-57 will help make your adventure the best one yet. It comes with an assortment of conveniences geared toward families, such as complimentary breakfast and a swimming pool. Also check out the deals at Beautiful Cabin Retreat. It offers a king bed, animal viewing activities and plenty of opportunities to spend time as a family.
Where can I find cheap hotels in Cairo?
At Travelocity you'll find really nice hotels in Cairo at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Cairo rather than in Cairo. We may find you even better rates, too.
How do I find the best Cairo hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Cairo then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Cairo?
The cheapest hotel in Cairo is $66. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Cairo?
There are 27 hotels in Cairo on Travelocity.
What are the best hotels in Cairo?
Cairo has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Cairo for you!
When is the best time to visit Cairo?
If you want the joy of a fun-filled trip in peak season, visit Cairo during June, July and August. If you'd prefer the peace of off-season, book a stay during quieter months, such as December, January and February.
When is the cheapest time to stay in Cairo?
Based on historic data is usually the cheapest month to visit Cairo. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Cairo?
There are multiple hotels in Cairo that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Cairo. We have plenty of kid-friendly hotels in Cairo to choose from on Travelocity!
Why book a hotel in Cairo through Travelocity?
Because we have the top hotels in Cairo! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Cairo on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Cairo hotel reviews by fellow wanderers

Charming cottage overlooking Lake Acre

Charming cottage overlooking Lake Acre

5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Such a beautiful and peaceful place to stay Suzzie is a great host I stay there once or twice a year for the past several years loved every minute can’t wait to go back"
A verified traveler stayed at Charming cottage overlooking Lake Acre
Charming cottage overlooking Lake Acre

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