Book Hotels in Clarksville, MO

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Clarksville hotels

Owl house was built for unplugging, relaxing & connecting with friends/family

Owl house was built for unplugging, relaxing & connecting with friends/family

Troy MO
$193 nightly
The price is $206 total per night from Apr 5 to Apr 6
$206 total
Apr 5 - Apr 6
Total with taxes and fees
A hot tub is available at this cabin.
Everything was pristine, expectations and needed details were clear, and when I had a questions I got a fairly quick reply!

Reviewed on Feb 27, 2026

Opens in a new windowOwl house was built for unplugging, relaxing & connecting with friends/family
The Nest, reconnect with that special someone in our charming birdhouse!

The Nest, reconnect with that special someone in our charming birdhouse!

Troy MO
$193 nightly
The price is $206 total per night from Apr 5 to Apr 6
$206 total
Apr 5 - Apr 6
Total with taxes and fees
A hot tub is available at this cabin.
Hot tub was great. Spiral staircase was very small and wobbly but overall an amazing place

Reviewed on Jan 11, 2026

Opens in a new windowThe Nest, reconnect with that special someone in our charming birdhouse!
The Eagles Nest Inn

The Eagles Nest Inn

3 out of 5
215 Georgia St Louisiana MO
Fully refundable
$96 nightly
The price is $109 total per night from Apr 5 to Apr 6
$109 total
Apr 5 - Apr 6
Total with taxes and fees
This inn features a restaurant and a virtual front desk. Take advantage of the free self parking.
Best place to stay in town!

Reviewed on Mar 19, 2026

Opens in a new windowThe Eagles Nest Inn
River's Edge Motel

River's Edge Motel

2 out of 5
201 Mansion St Louisiana MO
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $91 total per night from Apr 4 to Apr 5
$91 total
Apr 4 - Apr 5
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Staff at the 24-hour front desk can provide around-the-clock ...
We were just driving through and needed a place to stay for the night. It was an easy check in and very friendly staff so perfect for us.

Reviewed on Mar 31, 2026

Opens in a new windowRiver's Edge Motel
Green Acres Hotel

Green Acres Hotel

2.5 out of 5
625 W. Washington Pittsfield IL
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $144 total per night from Apr 5 to Apr 6
$144 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free continental breakfast each morning. A garden, a lobby ...
Good place to stay!

Reviewed on Feb 27, 2026

Opens in a new windowGreen Acres Hotel
Unique 3-bed, 4-bath Home in Charming Clarksville MO

Unique 3-bed, 4-bath Home in Charming Clarksville MO

Clarksville MO
This vacation home features laundry facilities.
Get rates
Opens in a new windowUnique 3-bed, 4-bath Home in Charming Clarksville MO
William Watson Hotel

William Watson Hotel

3 out of 5
105 East Washington Street Pittsfield IL
$78 nightly
The price is $86 total per night from Apr 15 to Apr 16
$86 total
Apr 15 - Apr 16
Total with taxes and fees
A gym is featured at this hotel, along with free parking. Guests will appreciate free perks like free self parking and WiFi in public areas. A snack bar/deli ...
Opens in a new windowWilliam Watson Hotel
Super 8 by Wyndham Bowling Green

Super 8 by Wyndham Bowling Green

2 out of 5
1216 E Champ Clark Dr Bowling Green MO
This hotel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free on-the-go breakfast each morning. A 24-hour business ...
Get rates
Opens in a new windowSuper 8 by Wyndham Bowling Green
Rodeway Inn Pittsfield

Rodeway Inn Pittsfield

2 out of 5
1238 W Washington St Pittsfield IL
$57 nightly
The price is $62 total per night from Apr 16 to Apr 17
$62 total
Apr 16 - Apr 17
Total with taxes and fees
Free self parking is available and the hotel's front desk is staffed around-the-clock. Guests will appreciate free perks like on-the-go breakfast and WiFi in ...
Opens in a new windowRodeway Inn Pittsfield
Don't see what you're looking for?
See all available properties in Clarksville
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Clarksville Hotel & Travel Guide\n

Researching the best way to spend time in Hannibal? With Travelocity, you'll discover several places to kick up your feet in Clarksville. You'll find 3 apartments and hotels located within 6-mile (10-kilometer) of the city center.

Some Travelocity-listed accommodation options located near the city center of Clarksville are the Rackheath House and Cedarcrest Manor.

You could check out the William Watson Hotel along with the Super 8 Bowling Green Mo. The William Watson Hotel is positioned 20 miles (32 kilometers) from downtown Clarksville. The Super 8 Bowling Green Mo, is 13 miles (21 kilometers) away. The Knights Inn Pittsfield as well as the Green Acres Hotel are alternate accommodation options worth checking out around Clarksville.

After you have spent time in Clarksville, put aside some time to discover the other great attractions St. Louis - Northeast Missouri has to offer. St. Louis - Northeast Missouri is home to prairies, and other interesting visitor sights are history museums. Modern visitors in this pocket of United States of America adore mountain biking, hiking and cycling.

There are a number of hotels in Quincy, IL, located 45 miles (76 kilometers) to the northwest of Clarksville. The Holiday Inn Quincy East and Fairfield Inn & Suites Quincy are a selection of the rooms here.

Just because you are on vacation, should not have to mean you can't expand your obsession with all things sport. Find Chaifetz Arena 60 miles (100 kilometers) to the southeast of Clarksville. Find accommodation in the middle of the action at the Four Seasons Hotel St Louis or the Grand Center Inn.

Before you and your family pack your bags for Clarksville, be sure to look through our Clarksville accommodation and city guide where you are able to find the inside scoop on all the attractions on offer.

Frequently asked questions

What are the top kid-friendly hotels in Clarksville?
Family trips are where treasured memories are made, but it's no secret that traveling with youngsters can be difficult. These kid-friendly Clarksville hotels come with perks designed to keep young and old alike comfortable and happy: The whole gang will love staying at Historic Mansion River Access-St Louis Area. Animal viewing activities and a king bed are just a couple of the things that help make this hotel a winner. Come see what our Historical town has to offer! is another great choice. After a big day of exploring, come home to your cozy room and amenities like animal viewing activities and a king bed.
Where can I find cheap hotels in Clarksville?
At Travelocity you'll find really nice hotels in Clarksville at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Clarksville rather than in Clarksville. We may find you even better rates, too.
How do I find the best Clarksville hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Clarksville then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Clarksville?
The cheapest hotel in Clarksville is $62. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Clarksville?
There are 33 hotels in Clarksville on Travelocity.
What are the best hotels in Clarksville?
Clarksville has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Clarksville for you!
When is the best time to visit Clarksville?
If you want the joy of a fun-filled trip in peak season, visit Clarksville during March, May and June. If you'd prefer the peace of off-season, book a stay during quieter months, such as December, January and February.
When is the cheapest time to stay in Clarksville?
Based on historic data is usually the cheapest month to visit Clarksville. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Clarksville?
There are multiple hotels in Clarksville that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Clarksville. We have plenty of kid-friendly hotels in Clarksville to choose from on Travelocity!
Why book a hotel in Clarksville through Travelocity?
Because we have the top hotels in Clarksville! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Clarksville on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Clarksville hotel reviews by fellow wanderers

River's Edge Motel

River's Edge Motel

5 out of 5
Posted 3 days ago
Travelocity Verified Review
"We were just driving through and needed a place to stay for the night. It was an easy check in and very friendly staff so perfect for us."
A verified traveler stayed at River's Edge Motel
River's Edge Motel

Explore More Ways to Travel with Travelocity