Explore top 2025 5 Star Hotels in Vatican City

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Top Vatican City 5 Star hotels

The Westin Excelsior, Rome

The Westin Excelsior, Rome

5 out of 5
Via Vittorio Veneto 125 Rome RM
Fully refundableReserve now, pay when you stay
$370 nightly
The price is $430 total per night from Dec 15 to Dec 16
$430 total
Dec 15 - Dec 16
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...
8.2/10 Very Good! (736 reviews)
Classy, centrally located hotel. We enjoyed our stay and the breakfast was good. Instant coffee not what we like but we put up with it for two days.

Reviewed on Nov 6, 2025

Opens in a new windowThe Westin Excelsior, Rome
NH Collection Roma Palazzo Cinquecento

NH Collection Roma Palazzo Cinquecento

5 out of 5
Piazza Dei Cinquecento, 90 Rome RM
Fully refundableReserve now, pay when you stay
$250 nightly
The price is $298 total per night from Dec 1 to Dec 2
$298 total
Dec 1 - Dec 2
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. There's ...
9/10 Wonderful! (999 reviews)
Nice hotel, great location.

Reviewed on Nov 11, 2025

Opens in a new windowNH Collection Roma Palazzo Cinquecento
Sofitel Rome Villa Borghese

Sofitel Rome Villa Borghese

5 out of 5
Via Lombardia 47 Rome RM
Fully refundableReserve now, pay when you stay
$337 nightly
The price is $393 total per night from Dec 18 to Dec 19
$393 total
Dec 18 - Dec 19
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Families will appreciate the onsite laundry facilities, kid-friendly dining, and in-room childcare. ...
9/10 Wonderful! (945 reviews)
Overall 10/10

Reviewed on Aug 27, 2025

Opens in a new windowSofitel Rome Villa Borghese
Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World

Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World

5 out of 5
Piazza Della Repubblica, 47 Rome RM
Fully refundableReserve now, pay when you stay
$574 nightly
The price is $655 total per night from Dec 20 to Dec 21
$655 total
Dec 20 - Dec 21
Total with taxes and fees
A full-service spa, 2 restaurants, and a gym are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, free WiFi in ...
9/10 Wonderful! (997 reviews)
I like the property

Reviewed on Sep 14, 2025

Opens in a new windowAnantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World
InterContinental Rome Ambasciatori Palace by IHG

InterContinental Rome Ambasciatori Palace by IHG

5 out of 5
Via V. Veneto 62 Rome RM
Fully refundable
$390 nightly
The price is $452 total per night from Dec 18 to Dec 19
$452 total
Dec 18 - Dec 19
Total with taxes and fees
The hotel's 24-hour gym, a rooftop terrace, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the free WiFi in public ...
9.4/10 Exceptional! (154 reviews)
Friendly staff, quick check in and our room was available in the morning

Reviewed on Nov 10, 2025

Opens in a new windowInterContinental Rome Ambasciatori Palace by IHG
W Rome

W Rome

5 out of 5
26/36 Via Liguria Rome RM
Fully refundableReserve now, pay when you stay
$421 nightly
The price is $486 total per night from Dec 8 to Dec 9
$486 total
Dec 8 - Dec 9
Total with taxes and fees
This hotel features 2 bars/lounges, a poolside bar, and a restaurant. Enjoy the 24-hour gym and perks like free WiFi. Enjoy the a rooftop terrace and conveniences ...
9.4/10 Exceptional! (202 reviews)
The staff on arrival and the check-in was very professional and friendly. The room was as usual clean and comfortable. The main restaurant breakfast buffet was first class and the dinner was also very good. The dinner menu needs more options. I had ordered and received four cappuccinos and ALL were ...

Reviewed on Oct 29, 2025

Opens in a new windowW Rome
Baglioni Hotel Regina - The Leading Hotels of the World

Baglioni Hotel Regina - The Leading Hotels of the World

5 out of 5
Via Vittorio Veneto 72 Rome RM
Fully refundableReserve now, pay when you stay
$478 nightly
The price is $549 total per night from Dec 15 to Dec 16
$549 total
Dec 15 - Dec 16
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities and in-room ...
8.8/10 Excellent! (486 reviews)
Not only are the rooms beautifully appointed, the food so delicious, a heavenly harp playing at brunch, the staff with impeccable, customer, service, and professionalism, everything about this hotel screams Luxury and comfort! I will definitely be back!

Reviewed on Nov 12, 2025

Opens in a new windowBaglioni Hotel Regina - The Leading Hotels of the World
Radisson Collection Hotel, Roma Antica

Radisson Collection Hotel, Roma Antica

5 out of 5
VIA DELLE BOTTEGHE OSCURE 46 Rome RM
Fully refundableReserve now, pay when you stay
$287 nightly
The price is $338 total per night from Dec 8 to Dec 9
$338 total
Dec 8 - Dec 9
Total with taxes and fees
This smoke-free hotel features 2 restaurants and 2 bars/lounges. Enjoy the a rooftop terrace and perks like free WiFi. Enjoy the steam room and conveniences ...
9.4/10 Exceptional! (140 reviews)
We had a lovely stay here, staff were really nice, gym was good and a perfect central location. Breakfast seemed very expensive at €38pp per day therefore we didn’t choose this option.

Reviewed on Nov 13, 2025

Opens in a new windowRadisson Collection Hotel, Roma Antica
Six Senses Rome

Six Senses Rome

5 out of 5
Piazza di San Marcello Rome RM
Fully refundableReserve now, pay when you stay
$1,084 nightly
The price is $1,216 total per night from Dec 3 to Dec 4
$1,216 total
Dec 3 - Dec 4
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Enjoy the a rooftop terrace and perks like free WiFi. You'll appreciate ...
9.4/10 Exceptional! (57 reviews)
Amazing staff, beautifully decorated hotel, super amenities. Truly wonderful find in the heart of Rome.

Reviewed on Nov 17, 2025

Opens in a new windowSix Senses Rome
Villa Agrippina Gran Meliá - The Leading Hotels of the World

Villa Agrippina Gran Meliá - The Leading Hotels of the World

5 out of 5
Via del Gianicolo 3 Rome RM
Fully refundableReserve now, pay when you stay
$512 nightly
The price is $586 total per night from Dec 3 to Dec 4
$586 total
Dec 3 - Dec 4
Total with taxes and fees
A full-service spa, 4 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Business travelers can take advantage of the free WiFi in public ...
9.2/10 Wonderful! (924 reviews)
Beautiful hotel, very clean, staff so friendly and helpful Would definitely stay again!

Reviewed on Nov 15, 2025

Opens in a new windowVilla Agrippina Gran Meliá - The Leading Hotels of the World
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Vatican City Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Vatican City to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Vatican City 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Vatican City before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Vatican City hotel reviews by fellow wanderers

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