Explore top 2026 4 Star Hotels in West Seneca

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Top West Seneca 4 Star hotels

The Delavan Hotel & Spa

The Delavan Hotel & Spa

4 out of 5
6461 Transit Road Bowmansville NY
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $153 total per night from May 27 to May 28
$153 total
May 27 - May 28
Total with taxes and fees
This smoke-free hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
9/10 Wonderful! (1,002 reviews)
Room was clean nice. No remote for television. Short on towels after the third day of stay.

Reviewed on May 15, 2026

Opens in a new windowThe Delavan Hotel & Spa
The Mansion On Delaware Ave

The Mansion On Delaware Ave

4 out of 5
414 Delaware Ave Buffalo NY
Fully refundableReserve now, pay when you stay
$229 nightly
The price is $263 total per night from May 20 to May 21
$263 total
May 20 - May 21
Total with taxes and fees
This hotel features a 24-hour gym and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
9.4/10 Exceptional! (1,001 reviews)
We really enjoyed our stay at The Mansion. It was perfectly located with free parking facilities. The only item I would give a one star to was their internet access. It was almost non-existant in the room. It was better downstairs but not much.

Reviewed on May 15, 2026

Opens in a new windowThe Mansion On Delaware Ave
The Mosey Buffalo Williamsville, Tapestry Collection by Hilton

The Mosey Buffalo Williamsville, Tapestry Collection by Hilton

4 out of 5
5195 Main Street Buffalo NY
Fully refundableReserve now, pay when you stay
$160 nightly
The price is $182 total per night from May 28 to May 29
$182 total
May 28 - May 29
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the indoor pool and perks like free self parking and free ...
9.4/10 Exceptional! (1,000 reviews)
Hotel room was huge! Very nice.

Reviewed on May 14, 2026

Opens in a new windowThe Mosey Buffalo Williamsville, Tapestry Collection by Hilton
DoubleTree by Hilton Hotel Buffalo - Amherst

DoubleTree by Hilton Hotel Buffalo - Amherst

4 out of 5
10 Flint Rd Buffalo NY
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $130 total per night from May 27 to May 28
$130 total
May 27 - May 28
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
7.8/10 Good! (1,002 reviews)
good

Reviewed on May 15, 2026

Opens in a new windowDoubleTree by Hilton Hotel Buffalo - Amherst
Reikart House, Buffalo, a Tribute Portfolio Hotel

Reikart House, Buffalo, a Tribute Portfolio Hotel

4 out of 5
5000 Main Street Buffalo NY
Fully refundableReserve now, pay when you stay
$269 nightly
The price is $306 total per night from May 25 to May 26
$306 total
May 25 - May 26
Total with taxes and fees
A restaurant and a gym are featured at this hotel. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free self ...
9.6/10 Exceptional! (712 reviews)
Amazing hotel. I do extensive traveling and this one is top notch.

Reviewed on May 7, 2026

Opens in a new windowReikart House, Buffalo, a Tribute Portfolio Hotel
The Westin Buffalo

The Westin Buffalo

4 out of 5
250 Delaware Ave Buffalo NY
Fully refundableReserve now, pay when you stay
$316 nightly
The price is $369 total per night from May 28 to May 29
$369 total
May 28 - May 29
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
9.2/10 Wonderful! (417 reviews)
Amazing hotel. Everything was super clean and nice.

Reviewed on Apr 12, 2026

Opens in a new windowThe Westin Buffalo
Buffalo Harmony House

Buffalo Harmony House

4.5 out of 5
70 Wadsworth Street Buffalo NY
$250 nightly
The price is $286 total per night from May 17 to May 18
$286 total
May 17 - May 18
Total with taxes and fees
Free WiFi in public areas, a garden, and a communal living room are available at this bed & breakfast. Enjoy the free full breakfast each morning. Express check-in, ...
10/10 Exceptional! (49 reviews)
Thank you so much for your gracious hospitality. The renovations that you have done on the house are great. Look forward to staying again.

Reviewed on Mar 5, 2026

Opens in a new windowBuffalo Harmony House
River Spring Lodge

River Spring Lodge

4 out of 5
1961A Church Road Darien Center NY
A restaurant, free self parking, and a 24-hour front desk are among this bed & breakfast's amenities. Guests will appreciate free perks like full breakfast and ...
10/10 Exceptional! (76 reviews)
Don’t miss this gem of a place!!
Five star bed and breakfast that was quiet, clean, comfortable, and had the absolute BEST breakfast ever!

Reviewed on Dec 1, 2024

Opens in a new windowRiver Spring Lodge
Lofts on Pearl Trademark Collection by Wyndham

Lofts on Pearl Trademark Collection by Wyndham

4 out of 5
92 Pearl Street Buffalo NY
This apartment features 2 restaurants, free WiFi in public areas, and a snack bar/deli. Dry cleaning, luggage storage, and free newspapers are also on ...
9.2/10 Wonderful! (520 reviews)
Great location
Very easy and fast check in. Property manager managed to find ways to connect with me after unable to contact Expedia that our original property is closed on Sunday and we have to move to another property. The info provided was accurate. The location is really good. Close to city and easy access ...

Reviewed on Oct 14, 2020

Opens in a new windowLofts on Pearl Trademark Collection by Wyndham
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4 Star Hotels West Seneca

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in West Seneca 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in West Seneca will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in West Seneca, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent West Seneca hotel reviews by fellow wanderers