Explore 28 Luxury Hotels in Southeastern Indiana
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Best Luxury Hotels in Southeastern Indiana

Galt House Hotel Trademark Collection by Wyndham
"We liked the convenience to the KFC Yum Center, but were disappointed with the cleanliness. Our whole floor and room smelled bad. Skittles on the floor in our room. No in room instructions on how to operate the atypical hvac thermostat (had to call for assistance) or television (normal operational ..."
Reviewed on Aug 4, 2026

Baymont by Wyndham Corydon
"Well maintained"
Reviewed on Aug 2, 2026

Econo Lodge Louisville Downtown
"Not at this moment"
Reviewed on Aug 4, 2026

21c Museum Hotel Louisville

West Baden Springs Hotel

The Brown Hotel

Embassy Suites Louisville Downtown

Seelbach Hilton Louisville Downtown
More 4 star hotels in Southeastern Indiana

The Pepin Mansion Historic B&B
Southeastern Indiana Luxury Hotels
Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Southeastern Indiana luxury hotels are the plush oasis you’ve been looking for.
Choose from the best luxury hotels in Southeastern Indiana to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.
We want you to enjoy your next vacation in style and the top luxury resorts in Southeastern Indiana will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Southeastern Indiana, and plan your next opulent escape.
Southeastern Indiana hotels essential information
Accommodation | 1,135 hotels |
|---|---|
Lowest Price | $75 |
Highest Price | $258 |
Popular hotels | 21c Museum Hotel Louisville, West Baden Springs Hotel, The Brown Hotel, Galt House Hotel Trademark Collection by Wyndham, Embassy Suites Louisville Downtown, Econo Lodge Louisville Downtown, Seelbach Hilton Louisville Downtown, Baymont by Wyndham Corydon |
Popular Luxury Stays in Southeastern Indiana
Recent Southeastern Indiana Hotel Reviews By Fellow Wanderers

Hampton Inn New Albany Louisville West
"Hampton Inn was at a good location for our stay. Wonderful staff and a big comfortable room. Fantastic breakfast for our family. The only downfall was it rained and the pool is a outdoor pool My grandson had a melt down over that but not Hampton Inn fault that it rained. We will definitely staff again and hope for no rain."









