Explore 28 Luxury Hotels in Southeastern Indiana

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Best Luxury Hotels in Southeastern Indiana

21c Museum Hotel Louisville

21c Museum Hotel Louisville

700 W Main Street, Louisville, KY
Fully refundableReserve now, pay when you stay
$174 nightly
The price is $205 total per night from Jun 15 to Jun 16
$205 total
Jun 15 - Jun 16
Total includes taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
9.2/10 Wonderful! (1,001 reviews)
"Dwight was the one person who made the hotel a 5 vs the overall 4 we gave it. He was extremely helpful in all situations Front desk attendants were not that helpful or seemed to always be “busy” $32 a night for valet parking was ridiculously high for the price for guest that stay there. Might even ..."

Reviewed on May 22, 2025

21c Museum Hotel Louisville
The Brown Hotel

The Brown Hotel

335 W Broadway, Louisville, KY
Fully refundableReserve now, pay when you stay
$179 nightly
The price is $211 total per night from May 29 to May 30
$211 total
May 29 - May 30
Total includes taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
9.2/10 Wonderful! (1,005 reviews)
Brown was fun
"Easy to chk in, easy to the room. Everything good except the hotel is getting a little tired. Many little things like paint and wear & tear not addressed. Enjoyed the stay with an ole girl but not her heyday anymore."

Reviewed on May 25, 2025

The Brown Hotel
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

140 North Fourth Street, Louisville, KY
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $169 total per night from Jun 13 to Jun 14
$169 total
Jun 13 - Jun 14
Total includes taxes and fees
A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
8.8/10 Excellent! (3,357 reviews)
"Amazing place to stay. Great service!"

Reviewed on May 22, 2025

Galt House Hotel Trademark Collection by Wyndham
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Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

501 South Fourth Street, Louisville, KY
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $139 total per night from Jun 22 to Jun 23
$139 total
Jun 22 - Jun 23
Total includes taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like on-the-go breakfast and WiFi in public areas. Valet ...
8.8/10 Excellent! (1,002 reviews)
"This is a great place to stay if you’re into walking through a downtown. Great staff and facility."

Reviewed on May 18, 2025

Embassy Suites Louisville Downtown
Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown

500 S 4th St, Louisville, KY
Fully refundableReserve now, pay when you stay
$168 nightly
The price is $198 total per night from Jun 1 to Jun 2
$198 total
Jun 1 - Jun 2
Total includes taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, express check-out, and ...
8.6/10 Excellent! (1,000 reviews)
"Wonderful hotel would definitely recomment it. Rooms do need some updates and TLC."

Reviewed on May 19, 2025

Seelbach Hilton Louisville Downtown
Baymont by Wyndham Corydon

Baymont by Wyndham Corydon

2495 Landmark Avenue NE, Corydon, IN
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $76 total per night from Jun 17 to Jun 18
$76 total
Jun 17 - Jun 18
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of ...
7.4/10 Good! (1,002 reviews)
"Everything we expected in a hotel"

Reviewed on May 22, 2025

Baymont by Wyndham Corydon
Econo Lodge Downtown Louisville

Econo Lodge Downtown Louisville

401 S 2nd St, Louisville, KY
Fully refundableReserve now, pay when you stay
$62 nightly
The price is $72 total per night from Jun 16 to Jun 17
$72 total
Jun 16 - Jun 17
Total includes taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the express check-out. ...
7.2/10 Good! (1,004 reviews)
"It was good but although it said non smoking the room smelled like smoke."

Reviewed on May 23, 2025

Econo Lodge Downtown Louisville
West Baden Springs Hotel

West Baden Springs Hotel

8538 W Baden Ave, West Baden Springs, IN
This luxury resort features a casino, a full-service spa, and 15 restaurants. Bring the family and enjoy the children's club, along with horse riding/rentals. ...
"The hotel West Baden is awesome they have 24 hour trolley that runs every 15 minutes and will take you anywhere in the area."

Reviewed on Dec 25, 2018

West Baden Springs Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Southeastern Indiana

Southeastern Indiana Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Southeastern Indiana luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Southeastern Indiana to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Southeastern Indiana will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Southeastern Indiana, and plan your next opulent escape.


Southeastern Indiana hotels essential information

Accommodation
1,028 hotels
Lowest Price
$72
Highest Price
$237
Popular hotels
21c Museum Hotel Louisville, West Baden Springs Hotel, The Brown Hotel, Galt House Hotel Trademark Collection by Wyndham, Embassy Suites Louisville Downtown, Econo Lodge Downtown Louisville, Seelbach Hilton Louisville Downtown, Baymont by Wyndham Corydon

Popular Luxury Stays in Southeastern Indiana

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