Explore 18 Luxury Hotels in South San Francisco

Name: Park Pointe Hotel
Price range: $110 total
Rating: 5.8

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Best Luxury Hotels in South San Francisco

Embassy Suites by Hilton San Francisco Airport Oyster Point

250 Gateway Blvd, South San Francisco, CA

Fully refundableReserve now, pay when you stay

$166 nightly

$194 total

Aug 4 - Aug 5

Total includes taxes and fees

This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

8.4/10 Very Good! (1,114 reviews)

"Very nice overall atmosphere in the hotel. Loved the complementary happy hour. Whether it was extra towels, questions about parking, the staff were polite and quickly responsive. The only minor negative was the room above us was children running around until midnight (thankfully only one of our two ..."

Reviewed on Jul 21, 2025

Hilton Garden Inn San Francisco Arpt North

670 Gateway Blvd, South San Francisco, CA

Fully refundableReserve now, pay when you stay

$102 nightly

$120 total

Jul 27 - Jul 28

Total includes taxes and fees

A restaurant and a gym are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Self parking, ...

8.4/10 Very Good! (1,004 reviews)

"Very friendly staff. Lauren was the lady checking me in with very warm welcome which made this hotel alive."

Reviewed on Jul 21, 2025

La Quinta Inn & Suites by Wyndham San Francisco Airport N

20 Airport Blvd, South San Francisco, CA

Fully refundableReserve now, pay when you stay

$122 nightly

$143 total

Jul 27 - Jul 28

Total includes taxes and fees

This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free ...

8/10 Very Good! (2,022 reviews)

"There’s a Denny’s right next door. Convenient location. Costco, Subway, Hertz, KFC, Taco Bell within walking distance. Cleaning lady a little too eager to get into our room. Very humid so carpet always felt damp. Maybe hardwood or laminate floors would be better suited. Ladies at front desk were ..."

Reviewed on Jul 20, 2025

Comfort Inn and Suites San Francisco Airport North

121 E Grand Ave, South San Francisco, CA

Fully refundableReserve now, pay when you stay

$105 nightly

$123 total

Jul 27 - Jul 28

Total includes taxes and fees

This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free airport pick-up. Business travelers can take advantage of the ...

7.8/10 Good! (1,003 reviews)

"Great"

Reviewed on Jul 20, 2025

Larkspur Landing Extended Stay Suites South San Francisco

690 Gateway Blvd, South San Francisco, CA

Fully refundableReserve now, pay when you stay

$90 nightly

$107 total

Aug 24 - Aug 25

Total includes taxes and fees

This hotel doesn't skimp on freebies - guests receive free breakfast and free WiFi. Traveling for business? Take advantage of the business center, laundry service, ...

7.8/10 Good! (1,006 reviews)

"The price"

Reviewed on Jul 20, 2025

Hotel Focus SFO

111 Mitchell Ave, South San Francisco, CA

Fully refundableReserve now, pay when you stay

$89 nightly

$105 total

Aug 15 - Aug 16

Total includes taxes and fees

This hotel features free WiFi in public areas, laundry facilities, and self parking. Enjoy freebies like on-the-go breakfast and a roundtrip airport shuttle ...

7.4/10 Good! (1,432 reviews)

"High value for the price. The hotel was clean, affordable and convenient. Shuttle was on time but hours are a bit strange. Not sure what other reviewers are expecting for this price since this hotel was perfect for a one night stay heading out early from SFO. I’d stay here again."

Reviewed on Jul 19, 2025

Travelodge by Wyndham San Francisco Airport North

326 S Airport Blvd, South San Francisco, CA

Fully refundableReserve now, pay when you stay

$74 nightly

$88 total

Jul 27 - Jul 28

Total includes taxes and fees

A restaurant and an outdoor pool are featured at this motel. Traveling on business? Take advantage of the free WiFi in public areas, conference space, and free ...

5.8/10 (2,466 reviews)

"I was hesitant about a SF hotel being from WI, but it held up to snuff. I grew up around hotel maids/rooms so I checked around, but I didn't notice anything remotely bothersome. The only thing eve"

Reviewed on Jul 23, 2025

Park Pointe Hotel

245 S Airport Blvd, South San Francisco, CA

Fully refundableReserve now, pay when you stay

$94 nightly

$110 total

Jul 25 - Jul 26

Total includes taxes and fees

This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. A lobby fireplace, a picnic area, and luggage storage are also on ...

5.8/10 (1,004 reviews)

"I like the fact that it was convenient to a lot of stores around and to SFO but I didn't like is that the outside property was like just like gold and like I don't know it needs to be upgraded"

Reviewed on Jul 7, 2025

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More 4 star hotels in South San Francisco

Grand Hyatt at SFO

55 S McDonnell Rd, San Francisco, CA

$278 nightly

$311 total

Aug 9 - Aug 10

Total includes taxes and fees

9.6/10 Exceptional! (1,381 reviews)

5 star hotels in South San Francisco

The Ritz-Carlton, San Francisco

600 Stockton St, San Francisco, CA

$347 nightly

$408 total

Aug 24 - Aug 25

Total includes taxes and fees

9.2/10 Wonderful! (1,000 reviews)

South San Francisco Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the South San Francisco luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in South San Francisco to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in South San Francisco will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in South San Francisco, and plan your next opulent escape.

South San Francisco hotels essential information

Accommodation	5,009 hotels
Lowest Price	$88
Highest Price	$464
Popular hotels	Travelodge by Wyndham San Francisco Airport North, Hotel Focus SFO, Comfort Inn and Suites San Francisco Airport North, Embassy Suites by Hilton San Francisco Airport Oyster Point, Hilton Garden Inn San Francisco Arpt North, Larkspur Landing Extended Stay Suites South San Francisco, Park Pointe Hotel, La Quinta Inn & Suites by Wyndham San Francisco Airport N

Popular Luxury Stays in South San Francisco

5 Stars Luxury stays in South San Francisco

Luxury stays in South San Francisco with spa

Recent South San Francisco Hotel Reviews By Fellow Wanderers

Holiday Inn Golden Gateway by IHG

5 out of 5

Posted 2 hours ago

Travelocity Verified Review

"Very friendly and professional front desk staff. Somehow I had two RSVP upon check-in, but they quickly addressed the issue. The room's great view (#2524) was dampended had was the last one at the end of the hallway (#2524), and is smaller than other rooms. Would have been nice to know that...I would have taken another room."

A verified traveler stayed at Holiday Inn Golden Gateway by IHG