Cheap Flights to São Tomé and Príncipe from $234 (2025/2026)

Wander Wisely with exceptional service, 24/7 supportOpens in a new window

Feel at ease with free flight cancellations within 24 hours of booking

Change your flight without a fee on select flights

How Much Does it Cost To Fly To São Tomé and Príncipe?

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Fri, Nov 14 - Fri, Nov 21
ACC
Kotoka Intl.
TMS
São Tomé Intl.
$350 Roundtrip, just found
$350
Roundtrip
just found
Select TAP Portugal flight, departing Fri, Nov 14 from Kotoka Intl. to São Tomé Intl., returning Fri, Nov 21, priced at $350 just found
Tue, Aug 19 - Tue, Aug 26
LBV
Leon M'ba Intl.
PCP
Príncipe Airport
$420 Roundtrip, found 2 days ago
$420
Roundtrip
found 2 days ago
Select APG Distribution System flight, departing Tue, Aug 19 from Leon M'ba Intl. to Príncipe Airport, returning Tue, Aug 26, priced at $420 found 2 days ago
Fri, Nov 14 - Fri, Nov 21
ACC
Kotoka Intl.
TMS
São Tomé Intl.
$422 Roundtrip, just found
$422
Roundtrip
just found
Select TAP Portugal flight, departing Fri, Nov 14 from Kotoka Intl. to São Tomé Intl., returning Fri, Nov 21, priced at $422 just found
Thu, Jul 10 - Sun, Jul 13
LBV
Leon M'ba Intl.
TMS
São Tomé Intl.
$485 Roundtrip, found 8 hours ago
$485
Roundtrip
found 8 hours ago
Select APG Distribution System flight, departing Thu, Jul 10 from Leon M'ba Intl. to São Tomé Intl., returning Sun, Jul 13, priced at $485 found 8 hours ago
Thu, Jul 10 - Sun, Jul 13
LBV
Leon M'ba Intl.
TMS
São Tomé Intl.
$502 Roundtrip, found 8 hours ago
$502
Roundtrip
found 8 hours ago
Select Hahn Air Systems flight, departing Thu, Jul 10 from Leon M'ba Intl. to São Tomé Intl., returning Sun, Jul 13, priced at $502 found 8 hours ago
Sun, Nov 9 - Wed, Nov 19
LIS
Humberto Delgado
TMS
São Tomé Intl.
$544 Roundtrip, found 6 days ago
$544
Roundtrip
found 6 days ago
Select TAAG Angola Airlines flight, departing Sun, Nov 9 from Humberto Delgado to São Tomé Intl., returning Wed, Nov 19, priced at $544 found 6 days ago
Tue, Aug 19 - Tue, Aug 26
LBV
Leon M'ba Intl.
PCP
Príncipe Airport
$690 Roundtrip, found 2 days ago
$690
Roundtrip
found 2 days ago
Select World Ticket Ltd flight, departing Tue, Aug 19 from Leon M'ba Intl. to Príncipe Airport, returning Tue, Aug 26, priced at $690 found 2 days ago
Thu, Jul 10 - Sun, Jul 13
LBV
Leon M'ba Intl.
TMS
São Tomé Intl.
$930 Roundtrip, found 8 hours ago
$930
Roundtrip
found 8 hours ago
Select Ethiopian Airlines flight, departing Thu, Jul 10 from Leon M'ba Intl. to São Tomé Intl., returning Sun, Jul 13, priced at $930 found 8 hours ago
Wed, Oct 22 - Wed, Oct 29
IAD
Washington Dulles Intl.
TMS
São Tomé Intl.
$1,394 Roundtrip, found 1 day ago
$1,394
Roundtrip
found 1 day ago
Select Air Canada flight, departing Wed, Oct 22 from Washington Dulles Intl. to São Tomé Intl., returning Wed, Oct 29, priced at $1,394 found 1 day ago
Mon, Oct 6 - Fri, Oct 10
JFK
John F. Kennedy Intl.
TMS
São Tomé Intl.
$1,552 Roundtrip, found 3 hours ago
$1,552
Roundtrip
found 3 hours ago
Select Air Canada flight, departing Mon, Oct 6 from John F. Kennedy Intl. to São Tomé Intl., returning Fri, Oct 10, priced at $1,552 found 3 hours ago
Sun, Oct 12 - Fri, Oct 31
ORD
O'Hare Intl.
TMS
São Tomé Intl.
$1,552 Roundtrip, found 1 day ago
$1,552
Roundtrip
found 1 day ago
Select Air Canada flight, departing Sun, Oct 12 from O'Hare Intl. to São Tomé Intl., returning Fri, Oct 31, priced at $1,552 found 1 day ago
OriginDestinationTravel DatesFlights From*
ACCSão ToméJuly 18 to July 20$578
LISSão ToméOctober 1 to October 12$670
LADSão ToméAugust 11 to August 15$955
EWRSão ToméJuly 11 to July 16$2,088
FRASão ToméAugust 1 to August 4$2,309
CDGSão ToméAugust 25 to August 31$2,355
*Prices include taxes and fees

Best São Tomé and Príncipe Flight and Hotel Packages

Price found within the past 48 hours. Click for updated prices.
Pestana Miramar São Tomé
3.0-star property

Pestana Miramar São Tomé

Aug 3 - Aug 9

6 night stay

Detroit (DTW) to São Tomé Island (TMS)

American Airlines • Coach

São Tomé Island (TMS) to Detroit (DTW)

TAP Portugal • Coach
per person
found 19 hours ago
Hotel Praia
3.5-star property

Hotel Praia

Aug 3 - Aug 9

6 night stay

Detroit (DTW) to São Tomé Island (TMS)

American Airlines • Coach

São Tomé Island (TMS) to Detroit (DTW)

TAP Portugal • Coach
per person
found 19 hours ago
Pestana São Tomé
5.0-star property

Pestana São Tomé

Aug 3 - Aug 9

6 night stay

Detroit (DTW) to São Tomé Island (TMS)

American Airlines • Coach

São Tomé Island (TMS) to Detroit (DTW)

TAP Portugal • Coach
per person
found 19 hours ago
Don't see what you're looking for?
See all available trips from Detroit to São Tomé and Príncipe
View all trips

Travelers ❤️ These São Tomé and Príncipe 🏨

Pestana São Tomé

Pestana São Tomé

5 out of 5
Avenida Marginal 12 De Julho, São Tomé
Stay at this 5-star luxury hotel in São Tomé. Enjoy free WiFi, free parking, and a beach locale. Popular attractions Estadio Nacional 12 de Julho and Cathedral of São Tomé are located nearby.
7.8/10 Good! (68 reviews)
"Good choice in São Tomé city."

Reviewed on Apr 5, 2025

Pestana São Tomé
Omali São Tomé – Principe Collection

Omali São Tomé – Principe Collection

4 out of 5
Praia Lagarto, São Tomé
Stay at this 4-star beach resort in São Tomé. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Cathedral of São Tomé and São Sebastião Museum are located nearby.
9.4/10 Exceptional! (58 reviews)
"The employees really make the property a superstar."

Reviewed on Feb 21, 2025

Omali São Tomé – Principe Collection
Pestana Miramar São Tomé

Pestana Miramar São Tomé

3 out of 5
Avenida Marginal 12 De Julho, São Tomé
Stay at this 3-star beach resort in São Tomé. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Estadio Nacional 12 de Julho and Cathedral of São Tomé are located nearby.
7/10 Good! (42 reviews)
"Very helpful and accommodating staff"

Reviewed on Jun 7, 2024

Pestana Miramar São Tomé
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Sundy Praia – Principe Collection

Sundy Praia – Principe Collection

5 out of 5
Praia Sundy, Príncipe Island
Stay at this 5-star luxury hotel in Príncipe Island. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Margarida Beach and Sundy Plantation are located nearby.
9.6/10 Exceptional! (5 reviews)
"Beautiful boutique property. So private in the rainforest with a beautiful beach where we didn’t see a single person all day. The staff is wonderful and the food was delicious. They do a 3 course meal every night for dinner and a lovely breakfast every morning. The staff’s little surprises throughout ..."

Reviewed on Jan 20, 2023

Sundy Praia – Principe Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Destinations in São Tomé and Príncipe

Top Flight Routes

Top Airlines

Top Airports

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.