Book Hotels in Carlisle, SC
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Top Carlisle hotels

A Taste of Southern Comfort
Carlisle SC
A gym is featured at this vacation home, along with laundry facilities and barbecue grills.
Welcome to SC
This was my first opportunity to live in SC and everything was great and I wanted for nothing, I would recommend this house if you want tranquility in the evening
Reviewed on Jun 28, 2025

Holiday Inn Express Richburg by IHG
3190 COMMERCE DRIVE Richburg SC
Fully refundable
$113 nightly
The price is $127 total per night from Jan 18 to Jan 19
$127 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Guests will appreciate freebies like full breakfast and free self parking. A 24-hour business center, ...
Great
Reviewed on Jan 1, 2026

Holiday Inn Express & Suites Newberry by IHG
121 Truman Ave Newberry SC
Fully refundable
$103 nightly
The price is $111 total per night from Jan 16 to Jan 17
$111 total
Jan 16 - Jan 17
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
The staff was very courteous, room was wonderful, breakfast was great, and the kids loved the pool area!
Reviewed on Jan 7, 2026

Hampton Inn Newberry-Opera House
1201 Nance St Newberry SC
$109 nightly
The price is $121 total per night from Jan 21 to Jan 22
$121 total
Jan 21 - Jan 22
Total with taxes and fees
This hotel features an outdoor pool and a gym. There's no skimping on freebies - guests receive free breakfast, free WiFi, and free self parking. A business ...
Great room; all associated with the hotel was excellent.
Reviewed on Jan 4, 2026

Quality Inn Union US Hwy 176
315 N Duncan Byp Union SC
Fully refundableReserve now, pay when you stay
$55 nightly
The price is $61 total per night from Feb 4 to Feb 5
$61 total
Feb 4 - Feb 5
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the express ...
Not crazy about breakfast. Room was very nice and staff was nice to
Reviewed on Dec 26, 2025

Quality Inn Clinton - Laurens I-26
105 Trade St Clinton SC
Fully refundableReserve now, pay when you stay
$66 nightly
The price is $73 total per night from Feb 2 to Feb 3
$73 total
Feb 2 - Feb 3
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Super clean and quiet and staff was extremely nice and friendly
Reviewed on Dec 18, 2025

Days Inn by Wyndham Richburg
3217 Lancaster Hwy Richburg SC
Fully refundableReserve now, pay when you stay
$55 nightly
The price is $62 total per night from Jan 18 to Jan 19
$62 total
Jan 18 - Jan 19
Total with taxes and fees
An outdoor pool is featured at this motel, along with free self parking. Guests will appreciate free perks like on-the-go breakfast and WiFi in public areas. ...
The room was clean with a pleasant order. No problems at check in. Good service.
Reviewed on Dec 12, 2025

Motel 6 Richburg, SC
2912 Parkway Blvd Chester SC
Fully refundableReserve now, pay when you stay
$58 nightly
The price is $65 total per night from Jan 15 to Jan 16
$65 total
Jan 15 - Jan 16
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A snack bar/deli is provided and the front desk is staffed ...
Staff are great and humble
Reviewed on Dec 31, 2025

Days Inn by Wyndham Clinton / Laurens I-26
12374 Highway 56 N Clinton SC
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $71 total per night from Jan 18 to Jan 19
$71 total
Jan 18 - Jan 19
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
Very clean room, very nice staff, House Keeping employees are excellent.
Reviewed on Dec 28, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Carlisle hotel reviews by fellow wanderers

Hampton Inn & Suites Clinton - I-26
5 out of 5
Posted 5 days ago
Travelocity Verified Review
"great staff"
A verified traveler stayed at Hampton Inn & Suites Clinton - I-26
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