Book Hotels in Carlisle, SC
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Top Carlisle hotels

A Taste of Southern Comfort
Carlisle
A gym is featured at this vacation home, along with laundry facilities and barbecue grills.
Welcome to SC
"This was my first opportunity to live in SC and everything was great and I wanted for nothing, I would recommend this house if you want tranquility in the evening"
Reviewed on Jun 28, 2025

Holiday Inn Express Richburg by IHG
3190 COMMERCE DRIVE, Richburg, SC
Fully refundable
$122 nightly
The price is $137 total per night from Oct 5 to Oct 6
$137 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Guests will appreciate freebies like full breakfast and free self parking. A 24-hour business center, ...
"Clean room, great staff, easy fast parking"
Reviewed on Sep 27, 2025

Holiday Inn Express & Suites Newberry by IHG
121 Truman Ave, Newberry, SC
Fully refundable
$123 nightly
The price is $133 total per night from Oct 19 to Oct 20
$133 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"Very clean and updated"
Reviewed on Sep 23, 2025

Hampton Inn Newberry-Opera House
1201 Nance St, Newberry, SC
$128 nightly
The price is $143 total per night from Oct 13 to Oct 14
$143 total
Oct 13 - Oct 14
Total with taxes and fees
This hotel features an outdoor pool and a gym. There's no skimping on freebies - guests receive free breakfast, free WiFi, and free self parking. A business ...
"Clean room, comfortable bed and friendly staff. Breakfast was good. Convenient to dining and the opera house"
Reviewed on Sep 28, 2025

Comfort Suites Clinton near Presbyterian College
12865 Hwy 56 N, Clinton, SC
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $122 total per night from Nov 2 to Nov 3
$122 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"Nice clean rooms. Very courteous staff and a great breakfast."
Reviewed on Sep 28, 2025

Quality Inn Clinton - Laurens I-26
105 Trade St, Clinton, SC
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $76 total per night from Oct 21 to Oct 22
$76 total
Oct 21 - Oct 22
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Good for what it is
"Everything was clean and updated with that said the bed frame made a awful noise every time you moved"
Reviewed on Sep 15, 2025

Days Inn by Wyndham Richburg
3217 Lancaster Hwy, Richburg, SC
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $70 total per night from Nov 2 to Nov 3
$70 total
Nov 2 - Nov 3
Total with taxes and fees
An outdoor pool is featured at this motel, along with free self parking. Guests will appreciate free perks like on-the-go breakfast and WiFi in public areas. ...
"Nice place"
Reviewed on Sep 25, 2025

Days Inn by Wyndham Clinton / Laurens I-26
12374 Highway 56 N, Clinton, SC
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $75 total per night from Oct 26 to Oct 27
$75 total
Oct 26 - Oct 27
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
"Quiet"
Reviewed on Sep 26, 2025

Quality Inn
1147 Wilson Rd, Newberry, SC
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $75 total per night from Oct 26 to Oct 27
$75 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"Clean rooms"
Reviewed on Sep 21, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Carlisle hotel reviews by fellow wanderers

Hampton Inn Newberry-Opera House
5 out of 5
Posted 4 days ago
Travelocity Verified Review
"Clean room, comfortable bed and friendly staff. Breakfast was good. Convenient to dining and the opera house "
A verified traveler stayed at Hampton Inn Newberry-Opera House
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