Southeast Missouri flight + hotel vacation packages
Price found within the past 48 hours. Click for updated prices.
The Cheshire
Save 100% on your flight
per person
Jul 19 - Jul 22
found 1 day ago
Roundtrip flight included
Philadelphia (PHL) to St. Louis (STL)
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the seasonal outdoor pool and free English breakfast each morning.
The Wildwood Hotel
Save 100% on your flight
per person
Jul 18 - Jul 22
found 1 day ago
Roundtrip flight included
Philadelphia (PHL) to St. Louis (STL)
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the spa tub and free perks like continental breakfast and free self parking.
Ameristar Casino Resort and Spa
Save 100% on your flight
per person
Jul 18 - Jul 22
found 1 day ago
Roundtrip flight included
Philadelphia (PHL) to St. Louis (STL)
This luxury hotel features a casino, a full-service spa, and 5 restaurants. Enjoy the 2 spa tubs and 24-hour gym, and unwind with a drink at the poolside bar.
The Pennywell St.Louis Downtown, a Hilton Hotel
Downtown St. Louis
per person
Jul 18 - Jul 22
found 1 day ago
Roundtrip flight included
Philadelphia (PHL) to St. Louis (STL)
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the express check-in, express check-out, and valet parking. Self parking, dry cleaning, and luggage storage are also offered.
The Royal Sonesta Chase Park Plaza St. Louis
Central West End
Save 100% on your flight
per person
Aug 28 - Aug 31
found 1 day ago
Roundtrip flight included
Philadelphia (PHL) to St. Louis (STL)
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Enjoy the seasonal outdoor pool and unwind at the bar/lounge and poolside bar.
Top Southeast Missouri hotels deals
Auburn Place Hotel And Suites
3265 William St, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
The price is $66 per night
$66
per night
Jul 14 - Jul 15
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the free buffet breakfast each morning.
Pool
Breakfast included
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
The price is $67 per night
$67
per night
Jun 20 - Jun 21
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the 3 onsite conference rooms. Enjoy the gym and conveniences like a 24-hour front desk and laundry facilities.
Breakfast included
Pet friendly
Motel 6 Poplar Bluff, MO
4101 Highway 67 N, Poplar Bluff, MO
Free Cancellation
Reserve now, pay when you stay
The price is $75 per night
$75
per night
Jul 4 - Jul 5
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Luggage storage is provided and the front desk is staffed around-the-clock.
Pet friendly
Parking included
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St, Farmington, MO
Free Cancellation
Reserve now, pay when you stay
The price is $55 per night
$55
per night
Jun 30 - Jul 1
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Pool
Breakfast included
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
The price is $64 per night
$64
per night
Jun 30 - Jul 1
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour business center. A gym and a safe deposit box are also provided.
Breakfast included
Pet friendly
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
The price is $99 per night
$99
per night
Jun 30 - Jul 1
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.
Pool
Breakfast included
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See all available properties in Southeast Missouri
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Meramec Caverns
5/5(21 reviews)
Explore the great outdoors at Meramec Caverns, a lovely green space in Sullivan. While in this family-friendly area, you can enjoy the coffeehouses.
Elephant Rocks State Park
5/5(13 reviews)
Explore the great outdoors at Elephant Rocks State Park, a lovely green space in Ironton. Make some time to visit the shops while you're in the area.
Ohio River
Commune with nature and explore the great outdoors at Ohio River during your travels in Valley Station. While you're in the area, wander around the parks.
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