American Airlines Flight DL4506 Deals & Information (2025/2026)

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American Airlines Flight 4506 Route Deals From $195

The cheapest prices found with in the last 7 days for return flights were $164 and $195 for one-way flights to Columbia Metropolitan for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Nov 5 - Tue, Nov 11
LGA
LaGuardia
CAE
Columbia Metropolitan
$164 Roundtrip, found 1 hour ago
$164
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Wed, Nov 5 from LaGuardia to Columbia Metropolitan, returning Tue, Nov 11, priced at $164 found 1 hour ago
Wed, Nov 5 - Tue, Nov 11
LGA
LaGuardia
CAE
Columbia Metropolitan
$210 Roundtrip, found 1 hour ago
$210
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Wed, Nov 5 from LaGuardia to Columbia Metropolitan, returning Tue, Nov 11, priced at $210 found 1 hour ago

Frequently asked questions

What route does flight number AA4506 take?
AA4506 serves multiple routes, but the most common is between Nashville International Airport and Raleigh, NC Airport (RDU-Raleigh - Durham Intl.). If on a non-stop flight, you'll disembark the plane in roughly 1 hour and 34 minutes. Multi-stop flights can also operate under the same number, as can services on other routes.
What kind of plane is on flight number AA4506?
AA4506 is a flight number that's used on many different routes. If you're booked on its most popular route, Nashville International Airport to Raleigh–Durham Airport, chances are you'll be boarding the Embraer 175.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA4506 flight with Travelocity, please visit our Customer Service Portal.