American Airlines Flight AA4506 Deals & Information (2025/2026)

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American Airlines Flight 4506 Route Deals From $189

The cheapest prices found with in the last 7 days for return flights were $161 and $189 for one-way flights to Columbia Metropolitan for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Aug 21 - Wed, Aug 27
LGA
LaGuardia
CAE
Columbia Metropolitan
$161 Roundtrip, found 3 days ago
$161
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Aug 21 from LaGuardia to Columbia Metropolitan, returning Wed, Aug 27, priced at $161 found 3 days ago
Thu, Sep 18 - Sat, Sep 20
LGA
LaGuardia
CAE
Columbia Metropolitan
$226 Roundtrip, found 17 hours ago
$226
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Thu, Sep 18 from LaGuardia to Columbia Metropolitan, returning Sat, Sep 20, priced at $226 found 17 hours ago
Tue, Oct 21 - Mon, Oct 27
LGA
LaGuardia
CAE
Columbia Metropolitan
$229 Roundtrip, found 3 hours ago
$229
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Tue, Oct 21 from LaGuardia to Columbia Metropolitan, returning Mon, Oct 27, priced at $229 found 3 hours ago

Frequently asked questions

What route does flight number AA4506 take?
AA4506 serves multiple routes, but the most common is between Nashville International Airport and Raleigh, NC Airport (RDU-Raleigh - Durham Intl.). If on a non-stop flight, you'll disembark the plane in roughly 1 hour and 34 minutes. Multi-stop flights can also operate under the same number, as can services on other routes.
What kind of plane is on flight number AA4506?
AA4506 is a flight number that's used on many different routes. If you're booked on its most popular route, Nashville International Airport to Raleigh–Durham Airport, chances are you'll be boarding the Embraer 175.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA4506 flight with Travelocity, please visit our Customer Service Portal.