American Airlines Flight AA4385 Deals & Information (2025/2026)

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American Airlines Flight 4385 Route Deals From $91

The cheapest prices found with in the last 7 days for return flights were $141 and $91 for one-way flights to Indianapolis Intl. for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Nov 5 - Wed, Nov 12
JFK
John F. Kennedy Intl.
IND
Indianapolis Intl.
$141 Roundtrip, just found
$141
Roundtrip
just found
Select American Airlines flight, departing Wed, Nov 5 from John F. Kennedy Intl. to Indianapolis Intl., returning Wed, Nov 12, priced at $141 just found
Wed, Oct 15 - Tue, Nov 11
JFK
John F. Kennedy Intl.
IND
Indianapolis Intl.
$151 Roundtrip, found 3 days ago
$151
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Oct 15 from John F. Kennedy Intl. to Indianapolis Intl., returning Tue, Nov 11, priced at $151 found 3 days ago
Wed, Oct 8 - Tue, Oct 14
JFK
John F. Kennedy Intl.
IND
Indianapolis Intl.
$161 Roundtrip, found 6 days ago
$161
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Oct 8 from John F. Kennedy Intl. to Indianapolis Intl., returning Tue, Oct 14, priced at $161 found 6 days ago
Sat, Nov 1 - Sat, Nov 8
JFK
John F. Kennedy Intl.
IND
Indianapolis Intl.
$172 Roundtrip, found 2 days ago
$172
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Nov 1 from John F. Kennedy Intl. to Indianapolis Intl., returning Sat, Nov 8, priced at $172 found 2 days ago
Thu, Feb 5 - Sun, Feb 8
JFK
John F. Kennedy Intl.
IND
Indianapolis Intl.
$173 Roundtrip, found 8 hours ago
$173
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Thu, Feb 5 from John F. Kennedy Intl. to Indianapolis Intl., returning Sun, Feb 8, priced at $173 found 8 hours ago
Tue, Oct 21 - Thu, Oct 23
JFK
John F. Kennedy Intl.
IND
Indianapolis Intl.
$173 Roundtrip, found 3 days ago
$173
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Oct 21 from John F. Kennedy Intl. to Indianapolis Intl., returning Thu, Oct 23, priced at $173 found 3 days ago
Sat, Nov 15 - Mon, Nov 24
JFK
John F. Kennedy Intl.
IND
Indianapolis Intl.
$174 Roundtrip, found 3 days ago
$174
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Nov 15 from John F. Kennedy Intl. to Indianapolis Intl., returning Mon, Nov 24, priced at $174 found 3 days ago
Mon, Oct 27 - Fri, Oct 31
JFK
John F. Kennedy Intl.
IND
Indianapolis Intl.
$182 Roundtrip, found 1 day ago
$182
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Oct 27 from John F. Kennedy Intl. to Indianapolis Intl., returning Fri, Oct 31, priced at $182 found 1 day ago
Sat, Nov 15 - Mon, Nov 24
JFK
John F. Kennedy Intl.
IND
Indianapolis Intl.
$184 Roundtrip, found 3 days ago
$184
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Nov 15 from John F. Kennedy Intl. to Indianapolis Intl., returning Mon, Nov 24, priced at $184 found 3 days ago
Wed, Oct 15 - Sat, Oct 18
JFK
John F. Kennedy Intl.
IND
Indianapolis Intl.
$187 Roundtrip, found 2 days ago
$187
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Oct 15 from John F. Kennedy Intl. to Indianapolis Intl., returning Sat, Oct 18, priced at $187 found 2 days ago

Frequently asked questions

What route does flight number AA4385 take?
AA4385 is used on a range of routes. More commonly, AA4385 flies straight from Charlotte-Douglas Intl. Airport (CLT) to DSM. If you have a ticket on this route, you'll be flying for approximately 2 hours and 38 minutes.
What kind of plane is on flight number AA4385?
There's a strong chance you'll be setting off on the Embraer 175 if you're jetting from Charlotte, NC Airport (CLT-Charlotte-Douglas Intl.) to Des Moines, IA Airport (DSM-Des Moines Intl.), the most popular route for flight AA4385.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA4385 flight with Travelocity, please visit our Customer Service Portal.