
$80 Cheap American Airlines flights from Tampa to San Diego (TPA to SAN)
Find The Best Day To Fly from Tampa to San Diego
Amazing American Airlines TPA to SAN Flight Deals
The cheapest flights to San Diego Intl. found within the past 7 days were $145 round trip and $80 one way. Prices and availability subject to change. Additional terms may apply.
SAN From TPA Economy Coach Packages on Similar Airlines



Frequently asked questions
Discover our best American Airlines flight from Tampa TPA to San Diego SAN
To find the best deals on flights to Tampa from San Diego with American Airlines, just enter your travel dates, filter by American Airlines, and hit search. You’ll find flights to choose from and can sort by price, flight duration, and arrival or departure time.
Return flights from Tampa TPA to San Diego SAN with American Airlines
If you’re planning a round trip, booking return flights with American Airlines is usually the most cost-effective option. With airfares ranging from $145 to $210, it’s easy to find a flight that suits your budget. Prices and availability subject to change. Additional terms may apply.
Book one-way American Airlines flights from Tampa TPA to San Diego SAN
A one-way ticket gives you much greater flexibility—allowing you to choose your return date, destination, and time whenever you’re ready. By booking in advance you can find great deals on one-way tickets too. Right now, a one-way American Airlines flight from Tampa to San Diego costs from $80. Prices and availability subject to change. Additional terms may apply.
The easy way to find cheap flights to San Diego SAN from Tampa TPA with American Airlines
To find a cheap American Airlines flight from Tampa TPA to San Diego SAN, sort your search results by price or filter by budget. Thanks to Travelocity’s Price Match Promise, if you find a better airfare deal anywhere else within 24 hours, we’ll credit or refund the difference.
How to find our best airfare deals on American Airlines flights from Tampa TPA to San Diego SAN
If you’re looking for cheap flights, it helps to be flexible when it comes to your travel dates. You’ll usually find lower cost tickets when you travel during quieter months such as August, or if you book a flight with a stopover.
Find nonstop flights from Tampa TPA to San Diego SAN with American Airlines
If you’re keen to be on San Diego soil fast, don’t waste time with a stopover—filter your search results to show direct American Airlines flights only. The journey takes around hour(s) min(s) – so you’ll be there before you know it.
Flexible airline tickets for American Airlines flights from Tampa TPA to San Diego SAN
Make sure you’re not out of pocket if plans change by choosing a flexible ticket with penalty-free amendment and cancellation options. Use our ‘no change fee’ filter to see which flights have this option.
There are a lot of reasons to book your flights to San Diego SAN from Tampa TPA with American Airlines on Travelocity
At Travelocity our vast and up-to-the-minute inventory puts all of our best flight deals in one place. So, whether you’re traveling on business or jetting off with friends and family, you can trust Travelocity to get you there.
Airport code | Country | Airport name | Number of flights |
---|---|---|---|
DFW | USA | Dallas-Fort Worth Intl. | 599 |
CLT | USA | Charlotte-Douglas Intl. | 536 |
ORD | USA | O'Hare Intl. | 317 |
PHL | USA | Philadelphia Intl. | 247 |
MIA | USA | Miami Intl. | 193 |
DCA | USA | Ronald Reagan Washington National | 152 |
PHX | USA | Sky Harbor Intl. | 141 |
LAX | USA | Los Angeles Intl. | 81 |
LGA | USA | LaGuardia | 72 |
BOS | USA | Logan Intl. | 57 |
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Popular American Airlines Flight Routes from TPA
Top American Airlines Flight Routes from SAN
- American Airlines SAN to LAS
- American Airlines SAN to ATL
- American Airlines SAN to PHX
- American Airlines SAN to EWR
- American Airlines SAN to PDX
- American Airlines SAN to AMS
- American Airlines SAN to CLT
- American Airlines SAN to SMF
- American Airlines SAN to MCO
- American Airlines SAN to ILM
- American Airlines SAN to JFK
Top Flights for American Airlines originating from TPA
Domestic
- Philadelphia to Orlando (PHL - MCO)
- Philadelphia to San Juan (PHL - SJU)
- New York to Mexico City (JFK - MEX)
- New York to Las Vegas (JFK - LAS)
- Chicago to Orlando (ORD - MCO)
- Boston to Orlando (BOS - MCO)
- Dallas to Las Vegas (DFW - LAS)
- Los Angeles to Honolulu (LAX - HNL)
- Los Angeles to Honolulu (LAX - HNL)
- Chicago to Orlando (ORD - MCO)
International
- Newark Liberty Intl. Airport to Miami (EWR - MIA)
- Orlando to San Juan (MCO - SJU)
- New York to Montego Bay (JFK - MBJ)
- Boston to Orlando (BOS - MCO)
- Los Angeles to Tokyo (LAX - HND)
- Newark Liberty Intl. Airport to Santo Domingo (EWR - SDQ)
- New York to Mexico City (JFK - MEX)
- Los Angeles to San Salvador (LAX - SAL)
- Philadelphia to San Juan (PHL - SJU)
- New York to San Juan (JFK - SJU)
Most Popular
- Atlanta to Miami (ATL - MIA)
- Philadelphia to Miami (PHL - MIA)
- JetBlue Airways Boston (BOS) to Orlando (MCO) flights
- Los Angeles to Chicago (LAX - ORD)
- Boston to Miami (BOS - MIA)
- Dallas to Atlanta (DFW - ATL)
- Chicago to Orlando (ORD - MCO)
- Los Angeles to Orlando (LAX - MCO)
- Boston to Los Angeles (BOS - LAX)
- Los Angeles to Miami (LAX - MIA)
- Los Angeles to Honolulu (LAX - HNL)
- Dallas to Orlando (DFW - MCO)
- Los Angeles to Dallas (LAX - DFW)
- Los Angeles to New York (LAX - JFK)
- San Francisco to Los Angeles (SFO - LAX)
- New York to Los Angeles (JFK - LAX)
- Atlanta to Los Angeles (ATL - LAX)
- Delta Minneapolis - St. Paul (MSP) to Las Vegas (LAS) flights
- New York to Orlando (JFK - MCO)
- New York to Miami (JFK - MIA)
- Hawaiian Airlines Orlando (MCO) to Honolulu (HNL) flights
- San Francisco to New York (SFO - JFK)
- Philadelphia to Orlando (PHL - MCO)
- Detroit to Orlando (DTW - MCO)
- Delta Detroit (DTW) to Las Vegas (LAS) flights
- Chicago to Los Angeles (ORD - LAX)
- New York to San Francisco (JFK - SFO)
- Los Angeles to San Francisco (LAX - SFO)
- Atlanta to Orlando (ATL - MCO)
- Dallas to Los Angeles (DFW - LAX)