
$175 Cheap American Airlines flights from Los Angeles to Knoxville (LAX to TYS)
Find The Best Day To Fly from Los Angeles to Knoxville
Amazing American Airlines LAX to TYS Flight Deals
The cheapest flights to McGhee Tyson found within the past 7 days were $289 round trip and $175 one way. Prices and availability subject to change. Additional terms may apply.
LAX
Los Angeles
TYS
Knoxville
$289 Roundtrip, found 18 hours ago
$289
Roundtrip
found 18 hours ago
LAX
Los Angeles
TYS
Knoxville
$294 Roundtrip, found 4 hours ago
$294
Roundtrip
found 4 hours ago
LAX
Los Angeles
TYS
Knoxville
$298 Roundtrip, found 1 day ago
$298
Roundtrip
found 1 day ago
LAX
Los Angeles
TYS
Knoxville
$299 Roundtrip, found 20 hours ago
$299
Roundtrip
found 20 hours ago
LAX
Los Angeles
TYS
Knoxville
$304 Roundtrip, found 2 days ago
$304
Roundtrip
found 2 days ago
LAX
Los Angeles
TYS
Knoxville
$314 Roundtrip, found 18 hours ago
$314
Roundtrip
found 18 hours ago
LAX
Los Angeles
TYS
Knoxville
$318 Roundtrip, found 4 hours ago
$318
Roundtrip
found 4 hours ago
LAX
Los Angeles
TYS
Knoxville
$319 Roundtrip, found 4 hours ago
$319
Roundtrip
found 4 hours ago
TYS From LAX Economy Coach Packages on Similar Airlines
Price found within the past 48 hours. Click for updated prices.



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See all available trips from Los Angeles Intl. to McGhee Tyson
View all tripsFrequently asked questions
Airport code | Country | Airport name | Number of flights |
---|---|---|---|
DFW | USA | Dallas-Fort Worth Intl. | 599 |
MIA | USA | Miami Intl. | 193 |
DCA | USA | Ronald Reagan Washington National | 152 |
PHX | USA | Sky Harbor Intl. | 141 |
BOS | USA | Logan Intl. | 57 |
Travelers ❤️ these 🏨 after their flight to Knoxville

Hilton Knoxville Airport
2001 Alcoa Hwy, Alcoa, TN
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9/10 Wonderful! (1,011 reviews)
"Great location to the airport and fantastic staff!"
Reviewed on Jul 15, 2025

La Quinta Inn & Suites by Wyndham Knoxville Airport
126 Cusick Road, Alcoa, TN
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free ...
8.6/10 Excellent! (1,477 reviews)
"Exactly what we needed for our business trip. Highly recommended ⭐️⭐️⭐️⭐️⭐️"
Reviewed on Jul 14, 2025

Best Western Knoxville Airport/Alcoa
162 Cusick Rd, Alcoa, TN
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport ...
8.4/10 Very Good! (1,008 reviews)
"Stay was quick no real complaints. Met our needs for the night breakfast was ok not bad but not great!"
Reviewed on Jul 13, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular American Airlines Flight Routes from LAX
- American Airlines LAX to BCN
- American Airlines LAX to ARN
- American Airlines LAX to BNE
- American Airlines LAX to CDG
- American Airlines LAX to HND
- American Airlines LAX to HEL
- American Airlines LAX to SAL
- American Airlines LAX to KIX
- American Airlines LAX to FRA
- American Airlines LAX to GUA
- American Airlines LAX to MEL
Top American Airlines Flight Routes from TYS
- American Airlines TYS to ALB
- American Airlines TYS to LAS
- American Airlines TYS to MIA
- American Airlines TYS to SJU
- American Airlines TYS to IAH
- American Airlines TYS to SFO
- American Airlines TYS to GRR
- American Airlines TYS to SMF
- American Airlines TYS to HNL
- American Airlines TYS to MSY
- American Airlines TYS to ORD
Top Flights for American Airlines originating from LAX
Domestic
- Dallas to Las Vegas (DFW - LAS)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- Newark Liberty Intl. Airport to San Juan (EWR - SJU)
- Los Angeles to Tokyo (LAX - NRT)
- Los Angeles to Honolulu (LAX - HNL)
- Newark Liberty Intl. Airport to Santiago (EWR - STI)
- Philadelphia to San Juan (PHL - SJU)
- Los Angeles to Paris (LAX - CDG)
- San Juan to Orlando (SJU - MCO)
- Los Angeles to San Salvador (LAX - SAL)
International
- Newark Liberty Intl. Airport to Santo Domingo (EWR - SDQ)
- Newark Liberty Intl. Airport to San Juan (EWR - SJU)
- Chicago to San Juan (ORD - SJU)
- Orlando to San Juan (MCO - SJU)
- Los Angeles to Tokyo (LAX - NRT)
- Philadelphia to San Juan (PHL - SJU)
- Ontario to San Salvador (ONT - SAL)
- Philadelphia to San Juan (PHL - SJU)
- Newark Liberty Intl. Airport to Santo Domingo (EWR - SDQ)
- San Juan to Orlando (SJU - MCO)
Most Popular
Flights
- Los Angeles to Chicago (LAX - ORD)
- Los Angeles to London (LAX - LHR)
- Los Angeles to Atlanta (LAX - ATL)
- Portland to Los Angeles (PDX - LAX)
- JetBlue Airways Boston (BOS) to Nashville (BNA) flights
- Houston to Los Angeles (IAH - LAX)
- Los Angeles to Cancun (LAX - CUN)
- Los Angeles to Paris (LAX - CDG)
- Los Angeles to Orlando (LAX - MCO)
- Boston to Los Angeles (BOS - LAX)
- Los Angeles to Miami (LAX - MIA)
- Los Angeles to Honolulu (LAX - HNL)
- Los Angeles to Dallas (LAX - DFW)
- Los Angeles to New York (LAX - JFK)
- San Francisco to Los Angeles (SFO - LAX)
- Orlando to Los Angeles (MCO - LAX)
- New York to Los Angeles (JFK - LAX)
- Los Angeles to Mexico City (LAX - MEX)
- Atlanta to Los Angeles (ATL - LAX)
- Phoenix to Los Angeles (PHX - LAX)
- San Francisco to New York (SFO - JFK)
- Salt Lake City to Los Angeles (SLC - LAX)
- Air India San Francisco (SFO) to Delhi (DEL) flights
- Los Angeles to Boston (LAX - BOS)
- Chicago to Los Angeles (ORD - LAX)
- Philadelphia to Los Angeles (PHL - LAX)
- New York to San Francisco (JFK - SFO)
- Los Angeles to Seattle (LAX - SEA)
- Los Angeles to San Francisco (LAX - SFO)
- Dallas to Los Angeles (DFW - LAX)