$173 Cheap American Airlines flights from Los Angeles to Knoxville (LAX to TYS)

Find The Best Day To Fly from Los Angeles to Knoxville

Amazing American Airlines LAX to TYS Flight Deals

The cheapest flights to McGhee Tyson found within the past 7 days were $299 round trip and $173 one way. Prices and availability subject to change. Additional terms may apply.

TYS From LAX Economy Coach Packages on Similar Airlines

Price found within the past 48 hours. Click for updated prices.
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Frequently asked questions

Can I catch a flight from Los Angeles Intl. Airport (LAX) to Knoxville Airport right now?
It’s always prudent to know about any quarantine requirements and travel advice reports in place in your destination. Make sure you check out our Covid-19 Travel Advisor for up-to-date information on booking a flight to McGhee Tyson Airport (TYS) from Los Angeles Intl. Airport (LAX).
What terminal is American Airlines at LAX?
Your ticket should be able to tell you which terminal your American Airlines flight will be boarding from at LAX. It might also be able to give you the arrival details for TYS. If not, it’s probably a wise idea to ask your airline before you fly.
Are there American Airlines non-stop flights from LAX to TYS?
If you’re traveling with American Airlines from Los Angeles Intl. Airport (LAX) to McGhee Tyson Airport (TYS), you’ll need to make a stopover. While you’re waiting for your connection, take the chance to pick up a snack or go for a walk.
How long is an American Airlines flight from LAX to TYS?
Lose yourself in a movie or two, enjoy some music or just put your seat back and drift off. Whatever you’re into, find a way to while away the 5 hours and 57 minutes that it takes to journey from Los Angeles Intl. Airport (LAX) to TYS with American Airlines.
How many direct and indirect flights does American Airlines fly from LAX to TYS?
When jetting from LAX to TYS, you’ll find at least 5 American Airlines daily flights to select from.
If I am not able to travel due to COVID-19, can I change my booking to a later date?
For more info about changing your flight to Knoxville Airport, please visit our Customer Service Portal.
What is the best day to buy a plane ticket?
This just in! Airfares offered on Thursdays tend to be the cheapest, according to flight demand on Travelocity in 2021. Tuesday and Wednesday prices are also good, but you may want to prepare your budget if booking during the weekend, as data shows that is when prices are generally at their highest.
What are the cheapest days to fly?
Frequent travelers may already know this, but earlier in the week can be the cheapest time to fly. In 2021, flights departing on a Monday were generally the cheapest of the week, whereas you may pay a premium for weekend flights when demand is usually high. On average, tickets were most expensive for Saturday departures, so if you need to fly out on a weekend, you might look for deals ahead of time.
How far in advance can you book a flight?
Trying to figure out how early you should book your flight? It’s possible to start comparing international airfares on Travelocity up to 12 months in advance. However, it does depend on the carrier as not all airlines release their prices that far out. According to our 2021 flight demand trends, last minute planners can still bag a bargain with some of the cheapest fares appearing 0-2 weeks prior to their travel dates.*According to flight demand on Travelocity.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Discover our best American Airlines flight from Los Angeles LAX to Knoxville TYS 

To find the best deals on flights to Los Angeles from Knoxville with American Airlines, just enter your travel dates, filter by American Airlines, and hit search. You’ll find flights to choose from and can sort by price, flight duration, and arrival or departure time.  

 

Return flights from Los Angeles LAX to Knoxville TYS with American Airlines 

If you’re planning a round trip, booking return flights with American Airlines is usually the most cost-effective option. With airfares ranging from $299 to $325, it’s easy to find a flight that suits your budget. Prices and availability subject to change. Additional terms may apply. 

 

Book one-way American Airlines flights from Los Angeles LAX to Knoxville TYS 

A one-way ticket gives you much greater flexibility—allowing you to choose your return date, destination, and time whenever you’re ready. By booking in advance you can find great deals on one-way tickets too. Right now, a one-way American Airlines flight from Los Angeles to Knoxville costs from $173. Prices and availability subject to change. Additional terms may apply. 

 

The easy way to find cheap flights to Knoxville TYS from  Los Angeles LAX with American Airlines 

To find a cheap American Airlines flight from Los Angeles LAX to Knoxville TYS, sort your search results by price or filter by budget. Thanks to Travelocity’s Price Match Promise, if you find a better airfare deal anywhere else within 24 hours, we’ll credit or refund the difference. 

 

How to find our best airfare deals on American Airlines flights from Los Angeles LAX to Knoxville TYS 

If you’re looking for cheap flights, it helps to be flexible when it comes to your travel dates. You’ll usually find lower cost tickets when you travel during quieter months such as October, or if you book a flight with a stopover. 

 

Find nonstop flights from Los Angeles LAX to Knoxville TYS with American Airlines 

If you’re keen to be on Knoxville soil fast, don’t waste time with a stopover—filter your search results to show direct American Airlines flights only. The journey takes around hour(s) min(s) – so you’ll be there before you know it. 

 

Flexible airline tickets for American Airlines flights from Los Angeles LAX to Knoxville TYS 

Make sure you’re not out of pocket if plans change by choosing a flexible ticket with penalty-free amendment and cancellation options. Use our ‘no change fee’ filter to see which flights have this option.  

 

There are a lot of reasons to book your flights to Knoxville TYS from  Los Angeles LAX with American Airlines on Travelocity 

At Travelocity our vast and up-to-the-minute inventory puts all of our best flight deals in one place. So, whether you’re traveling on business or jetting off with friends and family, you can trust Travelocity to get you there.

Travelers ❤️ these 🏨 after their flight to Knoxville

Hilton Knoxville Airport
Hilton Knoxville Airport
3.5 out of 5
2001 Alcoa Hwy, Alcoa, TN
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9/10 Wonderful! (1,004 reviews)
"It was a super convenient hotel connected by a walkway to the airport. The parking is not ideal as you have to lug your luggage upstairs and through the conference center where there were activities happening. With my flight delay it was very convenient to be so close"

Reviewed on May 7, 2025

Hilton Knoxville Airport
La Quinta Inn & Suites by Wyndham Knoxville Airport
La Quinta Inn & Suites by Wyndham Knoxville Airport
2.5 out of 5
126 Cusick Road, Alcoa, TN
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free ...
8.6/10 Excellent! (1,409 reviews)
Brighten it up a bit
"It was dark. The hallways. The room. Need more light or brighter lights or something. Other than that I was pleasantly surprised. Very comfortable. Very affordable."

Reviewed on May 6, 2025

La Quinta Inn & Suites by Wyndham Knoxville Airport
Best Western Knoxville Airport/Alcoa
Best Western Knoxville Airport/Alcoa
2.5 out of 5
162 Cusick Rd, Alcoa, TN
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport ...
8.4/10 Very Good! (1,001 reviews)
"Great! Would come again!!"

Reviewed on May 6, 2025

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.