
$81 Cheap American Airlines flights from Des Moines to Greenville (DSM to GSP)
Find The Best Day To Fly from Des Moines to Greenville
Amazing American Airlines DSM to GSP Flight Deals
The cheapest flights to Greenville-Spartanburg Intl. found within the past 7 days were $172 round trip and $81 one way. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Discover our best American Airlines flight from Des Moines DSM to Greenville GSP
To find the best deals on flights to Des Moines from Greenville with American Airlines, just enter your travel dates, filter by American Airlines, and hit search. You’ll find flights to choose from and can sort by price, flight duration, and arrival or departure time.
Return flights from Des Moines DSM to Greenville GSP with American Airlines
If you’re planning a round trip, booking return flights with American Airlines is usually the most cost-effective option. With airfares ranging from $172 to $251, it’s easy to find a flight that suits your budget. Prices and availability subject to change. Additional terms may apply.
Book one-way American Airlines flights from Des Moines DSM to Greenville GSP
A one-way ticket gives you much greater flexibility—allowing you to choose your return date, destination, and time whenever you’re ready. By booking in advance you can find great deals on one-way tickets too. Right now, a one-way American Airlines flight from Des Moines to Greenville costs from $81. Prices and availability subject to change. Additional terms may apply.
The easy way to find cheap flights to Greenville GSP from Des Moines DSM with American Airlines
To find a cheap American Airlines flight from Des Moines DSM to Greenville GSP, sort your search results by price or filter by budget. Thanks to Travelocity’s Price Match Promise, if you find a better airfare deal anywhere else within 24 hours, we’ll credit or refund the difference.
How to find our best airfare deals on American Airlines flights from Des Moines DSM to Greenville GSP
If you’re looking for cheap flights, it helps to be flexible when it comes to your travel dates. You’ll usually find lower cost tickets when you travel during quieter months such as September, or if you book a flight with a stopover.
Find nonstop flights from Des Moines DSM to Greenville GSP with American Airlines
If you’re keen to be on Greenville soil fast, don’t waste time with a stopover—filter your search results to show direct American Airlines flights only. The journey takes around hour(s) min(s) – so you’ll be there before you know it.
Flexible airline tickets for American Airlines flights from Des Moines DSM to Greenville GSP
Make sure you’re not out of pocket if plans change by choosing a flexible ticket with penalty-free amendment and cancellation options. Use our ‘no change fee’ filter to see which flights have this option.
There are a lot of reasons to book your flights to Greenville GSP from Des Moines DSM with American Airlines on Travelocity
At Travelocity our vast and up-to-the-minute inventory puts all of our best flight deals in one place. So, whether you’re traveling on business or jetting off with friends and family, you can trust Travelocity to get you there.
Airport code | Country | Airport name | Number of flights |
---|---|---|---|
DFW | USA | Dallas-Fort Worth Intl. | 599 |
CLT | USA | Charlotte-Douglas Intl. | 536 |
ORD | USA | O'Hare Intl. | 317 |
PHL | USA | Philadelphia Intl. | 247 |
MIA | USA | Miami Intl. | 193 |
DCA | USA | Ronald Reagan Washington National | 152 |
PHX | USA | Sky Harbor Intl. | 141 |
LAX | USA | Los Angeles Intl. | 81 |
LGA | USA | LaGuardia | 72 |
BOS | USA | Logan Intl. | 57 |
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Popular American Airlines Flight Routes from DSM
Top American Airlines Flight Routes from GSP
- American Airlines GSP to PHL
- American Airlines GSP to MIA
- American Airlines GSP to DCA
- American Airlines GSP to SGN
- American Airlines GSP to LGA
- American Airlines GSP to SAT
- American Airlines GSP to LHR
- American Airlines GSP to MCO
- American Airlines GSP to JAC
- American Airlines GSP to PSP
- American Airlines GSP to ALB
Top Flights for American Airlines originating from DSM
Domestic
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- New York to Santiago (JFK - STI)
- Chicago to Orlando (ORD - MCO)
- Newark Liberty Intl. Airport to Santiago (EWR - STI)
- Chicago to Las Vegas (ORD - LAS)
- Ontario to San Salvador (ONT - SAL)
- Chicago to Orlando (ORD - MCO)
- Orlando to San Juan (MCO - SJU)
- Newark Liberty Intl. Airport to Santo Domingo (EWR - SDQ)
International
- Newark Liberty Intl. Airport to Las Vegas (EWR - LAS)
- Ontario to San Salvador (ONT - SAL)
- Chicago to Mexico City (ORD - MEX)
- Newark Liberty Intl. Airport to San Juan (EWR - SJU)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- Dallas to Las Vegas (DFW - LAS)
- Chicago to Mexico City (ORD - MEX)
- New York to Santiago (JFK - STI)
- Los Angeles to San Salvador (LAX - SAL)
- Philadelphia to Orlando (PHL - MCO)
Most Popular
- San Diego to Charleston (SAN - CHS)
- Charleston to Atlanta (CHS - ATL)
- Atlanta to Charleston (ATL - CHS)
- Charleston to New York (CHS - JFK)
- Boston to Myrtle Beach (BOS - MYR)
- Detroit to Charleston (DTW - CHS)
- Des Moines to Orlando (DSM - MCO)
- Hartford to Myrtle Beach (BDL - MYR)
- Atlanta to Myrtle Beach (ATL - MYR)
- Des Moines to Phoenix (DSM - PHX)
- New York to Charleston (JFK - CHS)
- Des Moines to Chicago (DSM - ORD)
- Newark Liberty Intl. Airport to Myrtle Beach (EWR - MYR)
- Charleston to Philadelphia (CHS - PHL)
- Chicago to Myrtle Beach (ORD - MYR)
- American Airlines New York (JFK) to Myrtle Beach (MYR) flights
- Baltimore to Myrtle Beach (BWI - MYR)
- Cleveland to Myrtle Beach (CLE - MYR)
- JetBlue Airways North Charleston (CHS) to Boston (BOS) flights
- Charleston to Miami (CHS - MIA)
- Chicago to Charleston (ORD - CHS)
- Syracuse to Myrtle Beach (SYR - MYR)
- Pittsburgh to Myrtle Beach (PIT - MYR)
- JetBlue Airways Boston (BOS) to North Charleston (CHS) flights
- JetBlue Airways Tampa (TPA) to North Charleston (CHS) flights
- Philadelphia to Charleston (PHL - CHS)
- Des Moines to Denver (DSM - DEN)
- Detroit to Myrtle Beach (DTW - MYR)
- Philadelphia to Myrtle Beach (PHL - MYR)
- Charleston to Orlando (CHS - MCO)