American Airlines Flight 4648 Deals & Information (2026/2027)

Wander Wisely with exceptional service, 24/7 supportOpens in a new window

Feel at ease with free flight cancellations within 24 hours of booking

Change your flight without a fee on select flights

American Airlines Flight 4648 Route Deals From $79

The cheapest prices found with in the last 7 days for return flights were $176 and $79 for one-way flights to Buffalo Niagara Intl. for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Jun 10 - Thu, Jun 11
LGA
LaGuardia
BUF
Buffalo Niagara Intl.
$176 Roundtrip, found 1 day ago
$176
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Jun 10 from LaGuardia to Buffalo Niagara Intl., returning Thu, Jun 11, priced at $176 found 1 day ago
Tue, Jun 9 - Wed, Jun 10
LGA
LaGuardia
BUF
Buffalo Niagara Intl.
$181 Roundtrip, found 2 days ago
$181
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Jun 9 from LaGuardia to Buffalo Niagara Intl., returning Wed, Jun 10, priced at $181 found 2 days ago
Tue, Jun 23 - Tue, Jun 30
LGA
LaGuardia
BUF
Buffalo Niagara Intl.
$189 Roundtrip, found 5 days ago
$189
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Jun 23 from LaGuardia to Buffalo Niagara Intl., returning Tue, Jun 30, priced at $189 found 5 days ago
Sat, Aug 29 - Mon, Aug 31
LGA
LaGuardia
BUF
Buffalo Niagara Intl.
$207 Roundtrip, found 6 days ago
$207
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sat, Aug 29 from LaGuardia to Buffalo Niagara Intl., returning Mon, Aug 31, priced at $207 found 6 days ago
Wed, Jul 8 - Fri, Jul 10
LGA
LaGuardia
BUF
Buffalo Niagara Intl.
$212 Roundtrip, found 14 hours ago
$212
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Wed, Jul 8 from LaGuardia to Buffalo Niagara Intl., returning Fri, Jul 10, priced at $212 found 14 hours ago
Fri, Jun 19 - Tue, Jun 23
LGA
LaGuardia
BUF
Buffalo Niagara Intl.
$217 Roundtrip, found 1 day ago
$217
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Jun 19 from LaGuardia to Buffalo Niagara Intl., returning Tue, Jun 23, priced at $217 found 1 day ago
Sat, Aug 29 - Mon, Aug 31
LGA
LaGuardia
BUF
Buffalo Niagara Intl.
$217 Roundtrip, found 6 days ago
$217
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sat, Aug 29 from LaGuardia to Buffalo Niagara Intl., returning Mon, Aug 31, priced at $217 found 6 days ago
Sat, Oct 10 - Tue, Oct 13
LGA
LaGuardia
BUF
Buffalo Niagara Intl.
$219 Roundtrip, found 2 days ago
$219
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Oct 10 from LaGuardia to Buffalo Niagara Intl., returning Tue, Oct 13, priced at $219 found 2 days ago
Wed, Jun 10 - Thu, Jun 11
LGA
LaGuardia
BUF
Buffalo Niagara Intl.
$222 Roundtrip, found 1 day ago
$222
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Jun 10 from LaGuardia to Buffalo Niagara Intl., returning Thu, Jun 11, priced at $222 found 1 day ago
Tue, Jun 30 - Thu, Jul 2
LGA
LaGuardia
BUF
Buffalo Niagara Intl.
$227 Roundtrip, found 1 day ago
$227
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Jun 30 from LaGuardia to Buffalo Niagara Intl., returning Thu, Jul 2, priced at $227 found 1 day ago
Sat, Oct 10 - Tue, Oct 13
LGA
LaGuardia
BUF
Buffalo Niagara Intl.
$229 Roundtrip, found 2 days ago
$229
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, Oct 10 from LaGuardia to Buffalo Niagara Intl., returning Tue, Oct 13, priced at $229 found 2 days ago
Wed, Aug 19 - Wed, Nov 18
LGA
LaGuardia
BUF
Buffalo Niagara Intl.
$232 Roundtrip, found 18 hours ago
$232
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Wed, Aug 19 from LaGuardia to Buffalo Niagara Intl., returning Wed, Nov 18, priced at $232 found 18 hours ago
Wed, Jun 10 - Thu, Jun 11
LGA
LaGuardia
BUF
Buffalo Niagara Intl.
$235 Roundtrip, found 1 day ago
$235
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Jun 10 from LaGuardia to Buffalo Niagara Intl., returning Thu, Jun 11, priced at $235 found 1 day ago
Sat, May 23 - Tue, May 26
LGA
LaGuardia
BUF
Buffalo Niagara Intl.
$236 Roundtrip, found 2 days ago
$236
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, May 23 from LaGuardia to Buffalo Niagara Intl., returning Tue, May 26, priced at $236 found 2 days ago

Frequently asked questions

What route does flight number AA4648 take?
AA4648 serves multiple routes, but the most common is between Charleston Intl. Airport (CHS) and Ronald Reagan Washington National Airport (DCA). If your flight is direct, you'll land in 1 hour and 37 minutes. Multi-stop flights can also operate under this number, as can services on other routes.
What kind of plane is on flight number AA4648?
If you've booked a ticket on flight AA4648 from CHS to National Airport, there's every chance you'll be aboard an Embraer 175. Flight AA4648 serves several routes, but this is the busiest.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA4648 flight with Travelocity, please visit our Customer Service Portal.