American Airlines Flight 4500 Deals & Information (2025/2026)

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American Airlines Flight 4500 Route Deals From $149

The cheapest prices found with in the last 7 days for return flights were $306 and $149 for one-way flights to Lambert-St. Louis Intl. for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Jan 17 - Sun, Jan 18
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$306 Roundtrip, found 5 days ago
$306
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Jan 17 from Logan Intl. to Lambert-St. Louis Intl., returning Sun, Jan 18, priced at $306 found 5 days ago
Sat, Jan 17 - Sun, Jan 18
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$315 Roundtrip, found 5 days ago
$315
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Jan 17 from Logan Intl. to Lambert-St. Louis Intl., returning Sun, Jan 18, priced at $315 found 5 days ago
Wed, Dec 31 - Thu, Jan 1
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$315 Roundtrip, found 10 hours ago
$315
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Wed, Dec 31 from Logan Intl. to Lambert-St. Louis Intl., returning Thu, Jan 1, priced at $315 found 10 hours ago
Sat, Jan 17 - Sun, Jan 18
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$328 Roundtrip, found 5 days ago
$328
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Jan 17 from Logan Intl. to Lambert-St. Louis Intl., returning Sun, Jan 18, priced at $328 found 5 days ago
Mon, Jan 26 - Tue, Jan 27
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$333 Roundtrip, found 4 days ago
$333
Roundtrip
found 4 days ago
Select American Airlines flight, departing Mon, Jan 26 from Logan Intl. to Lambert-St. Louis Intl., returning Tue, Jan 27, priced at $333 found 4 days ago
Sat, Jan 17 - Sun, Jan 18
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$338 Roundtrip, found 5 days ago
$338
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sat, Jan 17 from Logan Intl. to Lambert-St. Louis Intl., returning Sun, Jan 18, priced at $338 found 5 days ago
Wed, Dec 31 - Thu, Jan 1
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$356 Roundtrip, found 10 hours ago
$356
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Wed, Dec 31 from Logan Intl. to Lambert-St. Louis Intl., returning Thu, Jan 1, priced at $356 found 10 hours ago
Wed, Dec 31 - Thu, Jan 1
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$357 Roundtrip, found 10 hours ago
$357
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Wed, Dec 31 from Logan Intl. to Lambert-St. Louis Intl., returning Thu, Jan 1, priced at $357 found 10 hours ago
Wed, Dec 31 - Thu, Jan 1
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$358 Roundtrip, found 10 hours ago
$358
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Wed, Dec 31 from Logan Intl. to Lambert-St. Louis Intl., returning Thu, Jan 1, priced at $358 found 10 hours ago
Wed, Dec 31 - Thu, Jan 1
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$366 Roundtrip, found 10 hours ago
$366
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Wed, Dec 31 from Logan Intl. to Lambert-St. Louis Intl., returning Thu, Jan 1, priced at $366 found 10 hours ago
Wed, Dec 31 - Thu, Jan 1
BOS
Logan Intl.
STL
Lambert-St. Louis Intl.
$397 Roundtrip, found 10 hours ago
$397
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Wed, Dec 31 from Logan Intl. to Lambert-St. Louis Intl., returning Thu, Jan 1, priced at $397 found 10 hours ago

Frequently asked questions

What route does flight number AA4500 take?
AA4500 takes several routes. The most frequently flown is between Indianapolis, IN Airport (IND-Indianapolis Intl.) and Charlotte-Douglas Intl. Airport (CLT), which flies direct. This service takes roughly 1 hour and 48 minutes. However, you might find other flights with this number that have one or more stops.
What kind of plane is on flight number AA4500?
It's likely you'll be traveling aboard an Embraer 175 if you're taking flight AA4500 from Indianapolis Intl. Airport (IND) to CLT. This is the most commonly used aircraft on this particular route.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA4500 flight with Travelocity, please visit our Customer Service Portal.