$242 Cheap American Airlines flights from Roanoke to Lexington (ROA to LEX)
Find The Best Day To Fly from Roanoke to Lexington
Amazing American Airlines ROA to LEX Flight Deals
The cheapest flights to Blue Grass found within the past 7 days were round trip and $242 one way. Prices and availability subject to change. Additional terms may apply.
Travelers ❤️ these 🏨 after their flight to Lexington
Courtyard Lexington Keeneland/Airport
3100 Wall St, Lexington, KY
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.6/10 Excellent! (752 reviews)
"This was an excellent hotel. Close to everything. Room was big and comfortable. Late night food and drinks were great and reasonable.! Staff was friendly and helpful. Would definitely stay here again."
Reviewed on Jul 14, 2025
Home2 Suites Lexington Keeneland Airport, KY
960 Midnight Pass, Lexington, KY
This hotel features an indoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. ...
9.6/10 Exceptional! (187 reviews)
"Nice location, very walkable to near by restaurants"
Reviewed on Jul 15, 2025
Comfort Suites Keeneland
3060 Fieldstone Way, Lexington, KY
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
7.8/10 Good! (1,007 reviews)
"A bit jaded"
Reviewed on Jul 17, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular American Airlines Flight Routes from ROA
Top American Airlines Flight Routes from LEX
Top Flights for American Airlines originating from ROA
Domestic
- New York to Orlando (LGA - MCO)
- New York to Las Vegas (JFK - LAS)
- Orlando to San Juan (MCO - SJU)
- Chicago to Las Vegas (ORD - LAS)
- Philadelphia to Orlando (PHL - MCO)
- Boston to Orlando (BOS - MCO)
- San Juan to Orlando (SJU - MCO)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- Los Angeles to San Salvador (LAX - SAL)
- Newark Liberty Intl. Airport to Las Vegas (EWR - LAS)
International
- Newark Liberty Intl. Airport to Santiago (EWR - STI)
- Orlando to San Juan (MCO - SJU)
- New York to Santiago (JFK - STI)
- New York to Santiago (JFK - STI)
- Boston to Orlando (BOS - MCO)
- Los Angeles to Honolulu (LAX - HNL)
- Atlanta to Las Vegas (ATL - LAS)
- Chicago to Las Vegas (ORD - LAS)
- San Juan to Orlando (SJU - MCO)
- Philadelphia to San Juan (PHL - SJU)
Most Popular
Flights
- Richmond to Atlanta (RIC - ATL)
- JetBlue Airways Richmond (RIC) to Las Vegas (LAS) flights
- JetBlue Airways Richmond (RIC) to Boston (BOS) flights
- Air India Delhi (DEL) to Chantilly (IAD) flights
- Richmond to Miami (RIC - MIA)
- Cincinnati to Denver (CVG - DEN)
- Cincinnati to Orlando (CVG - MCO)
- Washington to Los Angeles (IAD - LAX)
- Delta Florence (CVG) to Seattle (SEA) flights
- Washington to Orlando (IAD - MCO)
- Los Angeles to Washington (LAX - IAD)
- Louisville to Orlando (SDF - MCO)
- Air India Chantilly (IAD) to Delhi (DEL) flights
- Norfolk to Orlando (ORF - MCO)
- Atlanta to Richmond (ATL - RIC)
- Cincinnati to Los Angeles (CVG - LAX)
- San Francisco to Washington (SFO - IAD)
- Cincinnati to Dallas (CVG - DFW)
- Washington to Dallas (IAD - DFW)
- Delta Florence (CVG) to Las Vegas (LAS) flights
- Norfolk to Atlanta (ORF - ATL)
- Washington to Hyderabad (IAD - HYD)
- Delta Florence (CVG) to Phoenix (PHX) flights
- Washington to San Diego (IAD - SAN)
- Cincinnati to Miami (CVG - MIA)
- JetBlue Airways Richmond (RIC) to Fort Lauderdale (FLL) flights
- Richmond to Orlando (RIC - MCO)
- Delta Florence (CVG) to Boston (BOS) flights
- Washington to London (IAD - LHR)
- Washington to Barcelona (IAD - BCN)