$92 Cheap American Airlines flights from Boston to Knoxville (BOS to TYS)

Find The Best Day To Fly from Boston to Knoxville

Amazing American Airlines BOS to TYS Flight Deals

The cheapest flights to McGhee Tyson found within the past 7 days were $185 round trip and $92 one way. Prices and availability subject to change. Additional terms may apply.

Sat, Feb 21 - Sat, Feb 28
BOS
Boston
TYS
Knoxville
$185 Roundtrip, found 3 days ago
$185
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Feb 21 from Boston to Knoxville, returning Sat, Feb 28, priced at $185 found 3 days ago
Sat, Feb 21 - Sat, Feb 28
BOS
Boston
TYS
Knoxville
$231 Roundtrip, found 3 days ago
$231
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Feb 21 from Boston to Knoxville, returning Sat, Feb 28, priced at $231 found 3 days ago
Sat, Feb 21 - Sat, Feb 28
BOS
Boston
TYS
Knoxville
$255 Roundtrip, found 3 days ago
$255
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Feb 21 from Boston to Knoxville, returning Sat, Feb 28, priced at $255 found 3 days ago
Tue, Sep 30 - Sat, Oct 18
BOS
Boston
TYS
Knoxville
$257 Roundtrip, found 6 days ago
$257
Roundtrip
found 6 days ago
Select American Airlines flight, departing Tue, Sep 30 from Boston to Knoxville, returning Sat, Oct 18, priced at $257 found 6 days ago
Sat, Feb 21 - Sat, Feb 28
BOS
Boston
TYS
Knoxville
$264 Roundtrip, found 3 days ago
$264
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Feb 21 from Boston to Knoxville, returning Sat, Feb 28, priced at $264 found 3 days ago
Sat, Nov 8 - Wed, Nov 12
BOS
Boston
TYS
Knoxville
$279 Roundtrip, found 5 hours ago
$279
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Sat, Nov 8 from Boston to Knoxville, returning Wed, Nov 12, priced at $279 found 5 hours ago

TYS From BOS Economy Coach Packages on Similar Airlines

Price found within the past 48 hours. Click for updated prices.
River Edge Inn

River Edge Inn

2 out of 5
Price was $769, price is now $524 per person
$524
per person
Oct 18 - Oct 22
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Knoxville (TYS)
The Ramsey Hotel & Convention Center

The Ramsey Hotel & Convention Center

3 out of 5
Price was $1,007, price is now $704 per person
$704
per person
Oct 6 - Oct 10
found 20 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Knoxville (TYS)
The Oliver Hotel

The Oliver Hotel

3.5 out of 5
Save 100% on your flight
Price was $1,399, price is now $1,001 per person
$1,001
per person
Oct 3 - Oct 7
found 6 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Knoxville (TYS)
Don't see what you're looking for?
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Frequently asked questions

Can I catch a flight from Logan Intl. Airport to Knoxville Airport right now?
For information on any current TYS quarantine requirements and travel advice, go to our Covid-19 Travel Advisor. Look before you arrange your flight, so you don't get caught out en route.
What terminal is American Airlines at BOS?
You should find out exactly which terminal American Airlines departs from at Logan Intl. Airport (BOS) once you've seen your ticket. The same can be said for information about your arrival at McGhee Tyson Airport (TYS). If you can't locate those details, get in touch with your airline.
Are there American Airlines non-stop flights from BOS to TYS?
You won't find any direct flights between Logan Intl. Airport (BOS) and McGhee Tyson Airport (TYS) with American Airlines. Be ready to make at least one stopover if you need to travel on this particular route and airline.
How long is an American Airlines flight from BOS to TYS?
Weather and wind ... They're just some factors that can influence how long you spend in your plane seat. However, a trip from Logan Intl. Airport (BOS) to McGhee Tyson Airport (TYS) with American Airlines takes around 3 hours and 40 minutes, so you'll have touched down and be in vacay mode in next to no time.
How many direct and indirect flights does American Airlines fly from BOS to TYS?
You can choose from 3 American Airlines flights daily from BOS to TYS.
If I am not able to travel due to COVID-19, can I change my booking to a later date?
For more info about changing your flight to Knoxville Airport, please visit our Customer Service Portal.
What is the best day to buy a plane ticket?
This just in! Airfares offered on Thursdays tend to be the cheapest, according to flight demand on Travelocity in 2021. Tuesday and Wednesday prices are also good, but you may want to prepare your budget if booking during the weekend, as data shows that is when prices are generally at their highest.
What are the cheapest days to fly?
Frequent travelers may already know this, but earlier in the week can be the cheapest time to fly. In 2021, flights departing on a Monday were generally the cheapest of the week, whereas you may pay a premium for weekend flights when demand is usually high. On average, tickets were most expensive for Saturday departures, so if you need to fly out on a weekend, you might look for deals ahead of time.
How far in advance can you book a flight?
Trying to figure out how early you should book your flight? It's possible to start comparing international airfares on Travelocity up to 12 months in advance. However, it does depend on the carrier as not all airlines release their prices that far out. According to our 2021 flight demand trends, last minute planners can still bag a bargain with some of the cheapest fares appearing 0-2 weeks prior to their travel dates.*According to flight demand on Travelocity.com from January to December 2021. Savings are subject to change based on departure location, date and destination.
American Airlines Airports
Hop on a(n) American Airlines flight today by flying to many destinations out of these domestic and international airports:
Airport code
Country
Airport name
Number of flights
DFWUSADallas-Fort Worth Intl.599
CLTUSACharlotte-Douglas Intl.536
ORDUSAO'Hare Intl.317
PHLUSAPhiladelphia Intl.247
MIAUSAMiami Intl.193
DCAUSARonald Reagan Washington National152
PHXUSASky Harbor Intl.141
LAXUSALos Angeles Intl.81
LGAUSALaGuardia72
BOSUSALogan Intl.57

Travelers ❤️ these 🏨 after their flight to Knoxville

La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road, Alcoa, TN
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free ...
8.8/10 Excellent! (1,584 reviews)
"Front desk person was super nice and friendly! Room was clean but there was a lingering smell in room and staircase. Venting in bathroom is nonexistent so when you take a shower the bathroom fogs up terribly."

Reviewed on Sep 16, 2025

La Quinta Inn & Suites by Wyndham Knoxville Airport
Hilton Knoxville Airport

Hilton Knoxville Airport

3.5 out of 5
2001 Alcoa Hwy, Alcoa, TN
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9/10 Wonderful! (1,005 reviews)
Vacation
"Solid stay. Cannot beat the ability to walk to the airport."

Reviewed on Sep 14, 2025

Hilton Knoxville Airport
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd, Alcoa, TN
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport ...
8.4/10 Very Good! (1,010 reviews)
"3 minutes to the airport. Parking was great. Room was nice and cool. Staff warm and welcoming. Breakfast good."

Reviewed on Sep 16, 2025

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.