Book Hotels in Seneca, MO

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Seneca hotels

River Bend Casino & Hotel

River Bend Casino & Hotel

2.5 out of 5
100 Jackpot Place Wyandotte OK
$85 nightly
The price is $92 total per night from Sep 1 to Sep 2
$92 total
Sep 1 - Sep 2
Total with taxes and fees
This smoke-free hotel's 2 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the free WiFi in ...
"Love this hotel, easy checkin and check out. Super nice staff!"

Reviewed on Aug 31, 2026

Opens in a new windowRiver Bend Casino & Hotel
Drury Inn & Suites Joplin

Drury Inn & Suites Joplin

3 out of 5
3601 S Range Line Rd Joplin MO
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $131 total per night from Sep 13 to Sep 14
$131 total
Sep 13 - Sep 14
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
"Fantastic hotel Breakfast was very good with nice variety Evening snack fireside was awesome Clean room Comfortable bed"

Reviewed on Aug 30, 2026

Opens in a new windowDrury Inn & Suites Joplin
Quality Inn Neosho

Quality Inn Neosho

2 out of 5
3085 Gardner Edgewood Dr Neosho MO
Fully refundable
$76 nightly
The price is $85 total per night from Sep 29 to Sep 30
$85 total
Sep 29 - Sep 30
Total with taxes and fees
A gym is featured at this motel, along with free self parking. Guests will appreciate free perks like continental breakfast and WiFi in public areas. A communal ...
"Very nice place to stay!!! Very friendly staff and clean rooms!!!"

Reviewed on Aug 31, 2026

Opens in a new windowQuality Inn Neosho
La Quinta Inn & Suites by Wyndham Joplin

La Quinta Inn & Suites by Wyndham Joplin

3 out of 5
3320 S Range Line Rd Joplin MO
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $101 total per night from Sep 7 to Sep 8
$101 total
Sep 7 - Sep 8
Total with taxes and fees
This hotel features an outdoor pool, an indoor pool, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Opens in a new windowLa Quinta Inn & Suites by Wyndham Joplin
Downstream Casino Resort

Downstream Casino Resort

3 out of 5
69300 E Nee Rd Quapaw OK
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $123 total per night from Sep 30 to Oct 1
$123 total
Sep 30 - Oct 1
Total with taxes and fees
This resort features a casino, a full-service spa, and 4 restaurants. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Opens in a new windowDownstream Casino Resort
Best Western The Oasis at Joplin

Best Western The Oasis at Joplin

2.5 out of 5
3508 S Rangeline Road Joplin MO
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $95 total per night from Sep 6 to Sep 7
$95 total
Sep 6 - Sep 7
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Opens in a new windowBest Western The Oasis at Joplin
Greenstay Hotel Joplin Missouri

Greenstay Hotel Joplin Missouri

2 out of 5
3510 S Range Line Rd Joplin MO
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $90 total per night from Sep 1 to Sep 2
$90 total
Sep 1 - Sep 2
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
Opens in a new windowGreenstay Hotel Joplin Missouri
Sleep Inn South Joplin

Sleep Inn South Joplin

2.5 out of 5
I-44 & SR-43 S Joplin MO
Fully refundable
$88 nightly
The price is $100 total per night from Sep 27 to Sep 28
$100 total
Sep 27 - Sep 28
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...
Opens in a new windowSleep Inn South Joplin
Holiday Inn Joplin by IHG

Holiday Inn Joplin by IHG

3 out of 5
3402 S Arizona Ave Joplin MO
Fully refundable
$117 nightly
The price is $133 total per night from Sep 27 to Sep 28
$133 total
Sep 27 - Sep 28
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Opens in a new windowHoliday Inn Joplin by IHG
Don't see what you're looking for?
See all available properties in Seneca
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Seneca?
From well-thought-out amenities to rooms with bunk beds, kid-friendly hotels come with features that can help transform a good family vacation into a fantastic one. These Seneca properties make traveling with children child's play: Log Home in the woods. Privacy, deer, "Little Paradise"you'll love country will help make your next trip the best one yet. It offers a host of conveniences aimed at families, such as a playground and cycling. Alternatively, spend your nights in Seneca at Sleep Inn South Joplin. Make the most of a swimming pool, complimentary breakfast and more here.
Where can I find cheap hotels in Seneca?
At Travelocity you'll find really nice hotels in Seneca at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Seneca rather than in Seneca. We may find you even better rates, too.
How do I find the best Seneca hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Seneca then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Seneca?
The cheapest hotel in Seneca is $85. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Seneca?
There are 292 hotels in Seneca on Travelocity.
What are the best hotels in Seneca?
Seneca has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Seneca for you!
When is the best time to visit Seneca?
If you want the joy of a fun-filled trip in peak season, visit Seneca during April, May and June. If you'd prefer the peace of off-season, book a stay during quieter months, such as November, December and January.
When is the cheapest time to stay in Seneca?
Based on historic data is usually the cheapest month to visit Seneca. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Seneca?
There are multiple hotels in Seneca that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Seneca. We have plenty of kid-friendly hotels in Seneca to choose from on Travelocity!
Why book a hotel in Seneca through Travelocity?
Because we have the top hotels in Seneca! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Seneca on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Seneca hotel reviews by fellow wanderers

Quality Inn Neosho

Quality Inn Neosho

5 out of 5
Posted 7 hours ago
Travelocity Verified Review
"Very nice place to stay!!! Very friendly staff and clean rooms!!!"
A verified traveler stayed at Quality Inn Neosho
Quality Inn Neosho

Explore More Ways to Travel with Travelocity