Book Hotels in Rensselaer, MO

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Top Rensselaer hotels

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West

2.5 out of 5
105 Lakeside Dr Hannibal MO
Fully refundable
$98 nightly
The price is $114 total per night from Feb 1 to Feb 2
$114 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Love that I could bring my cat. This is 4th stay, largely due to the cost of a pet. The hotell is clean and I feel safe. Nice having restaurants so close. Will stay again on my next cross country trip.

Reviewed on Jan 13, 2026

Opens in a new windowSleep Inn & Suites Hannibal West
Lighthouse Inn & Suites

Lighthouse Inn & Suites

4 out of 5
612 Mark Twain Ave Hannibal MO
Fully refundableReserve now, pay when you stay
$188 nightly
The price is $215 total per night from Jan 21 to Jan 22
$215 total
Jan 21 - Jan 22
Total with taxes and fees
This aparthotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Dry cleaning is also provided.
Nice room. Matched the pictures. Exactly what we were looking for.

Reviewed on Jan 18, 2026

Opens in a new windowLighthouse Inn & Suites
Heritage Hotel Quincy

Heritage Hotel Quincy

2 out of 5
300 Gardner Expy Quincy IL
Fully refundableReserve now, pay when you stay
$66 nightly
The price is $75 total per night from Jan 21 to Jan 22
$75 total
Jan 21 - Jan 22
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free English breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
Great hotel clean and quiet

Reviewed on Jan 20, 2026

Opens in a new windowHeritage Hotel Quincy
Best Western On The River

Best Western On The River

2.5 out of 5
401 North 3rd Street Hannibal MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $113 total per night from Jan 25 to Jan 26
$113 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the seasonal ...
Tony was amazing when we checked in! Very clean and comfortable room!

Reviewed on Jan 18, 2026

Opens in a new windowBest Western On The River
Quality Inn & Suites Quincy - Downtown

Quality Inn & Suites Quincy - Downtown

2.5 out of 5
225 South 4th Street Quincy IL
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $121 total per night from Feb 19 to Feb 20
$121 total
Feb 19 - Feb 20
Total with taxes and fees
A gym is featured at this hotel, along with free self parking. Guests will appreciate free perks like on-the-go breakfast and WiFi in public areas. A safe deposit ...
We liked the hotel and the location. I'd recommend a second coffee carafe in the morning. During the breakfast times, it was repeatedly empty.

Reviewed on Nov 20, 2025

Opens in a new windowQuality Inn & Suites Quincy - Downtown
Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

2.5 out of 5
120 Lindsey Drive Hannibal MO
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $88 total per night from Feb 1 to Feb 2
$88 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
Clean and comfortable. Nice hot breakfast. Great staff, very friendly and welcoming.

Reviewed on Jan 15, 2026

Opens in a new windowQuality Inn & Suites Hannibal West
Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal

2.5 out of 5
4000 Market St Hannibal MO
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $89 total per night from Feb 5 to Feb 6
$89 total
Feb 5 - Feb 6
Total with taxes and fees
A full-service spa and an indoor pool are featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public ...
Clean room

Reviewed on Jan 12, 2026

Opens in a new windowComfort Inn & Suites - Hannibal
Microtel Inn & Suites by Wyndham Quincy Downtown/River Area

Microtel Inn & Suites by Wyndham Quincy Downtown/River Area

2.5 out of 5
200 S 3rd St Quincy IL
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $81 total per night from Jan 26 to Jan 27
$81 total
Jan 26 - Jan 27
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Clean rooms

Reviewed on Jan 7, 2026

Opens in a new windowMicrotel Inn & Suites by Wyndham Quincy Downtown/River Area
Motel 6 Hannibal, MO

Motel 6 Hannibal, MO

2 out of 5
123 Huckleberry Heights Dr Hannibal MO
Fully refundableReserve now, pay when you stay
$58 nightly
The price is $66 total per night from Feb 14 to Feb 15
$66 total
Feb 14 - Feb 15
Total with taxes and fees
A restaurant, free self parking, and a 24-hour front desk are among this motel's amenities. WiFi in public areas is free. A snack bar/deli and a fireplace in ...
Staff was great and the room was clean. Water could have been hotter

Reviewed on Jan 12, 2026

Opens in a new windowMotel 6 Hannibal, MO
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Rensselaer?
From cool amenities to extra space, kid-friendly hotels come with features that can help transform a nice family vacation into an incredible one. These Rensselaer options make getting away with little ones a piece of cake: Holiday Inn Express And Suites Hannibal - Medical Center, an IHG Hotel will help make your break the best one yet. It features an assortment of nice little touches, such as a swimming pool and complimentary breakfast. Alternatively, spend your Rensselaer break at Sleep Inn & Suites. Take advantage of a swimming pool, complimentary breakfast and more here.
Where can I find cheap hotels in Rensselaer?
At Travelocity you'll find really nice hotels in Rensselaer at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Rensselaer rather than in Rensselaer. We may find you even better rates, too.
How do I find the best Rensselaer hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Rensselaer then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Rensselaer?
The cheapest hotel in Rensselaer is $66. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Rensselaer?
There are 105 hotels in Rensselaer on Travelocity.
What are the best hotels in Rensselaer?
Rensselaer has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Rensselaer for you!
When is the best time to visit Rensselaer?
If you want the joy of a fun-filled trip in peak season, visit Rensselaer during March, May and June. If you'd prefer the peace of off-season, book a stay during quieter months, such as December, January and February.
When is the cheapest time to stay in Rensselaer?
Based on historic data is usually the cheapest month to visit Rensselaer. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Rensselaer?
There are multiple hotels in Rensselaer that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Rensselaer. We have plenty of kid-friendly hotels in Rensselaer to choose from on Travelocity!
Why book a hotel in Rensselaer through Travelocity?
Because we have the top hotels in Rensselaer! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Rensselaer on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Rensselaer hotel reviews by fellow wanderers

Heritage Hotel Quincy

Heritage Hotel Quincy

5 out of 5
Posted 22 hours ago
Travelocity Verified Review
"Great hotel clean and quiet "
A verified traveler stayed at Heritage Hotel Quincy
Heritage Hotel Quincy