A brick-paved street lined with historic buildings and a yellow fire hydrant.

Book a hotel near Historic Main Street, St. Charles Historic District

Name: Ameristar Casino Resort and Spa
Price range: $213 total

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Top hotels close to Historic Main Street

1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.

St. Charles MO

0.1 mi from Historic Main Street

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A hot tub is featured at this vacation home, along with a garden and laundry facilities. Barbecue grills are provided for your convenience.

Hot Tub

Kitchen

Luxurious, spa-like retreat steps from Main St.

Saint Charles MO

0.11 mi from Historic Main Street

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A water park and a hot tub are featured at this smoke-free vacation home. Enjoy the sauna and conveniences like a garden and laundry facilities.

Hot Tub

Kitchen

The Rustic Revival | Charming 2BR Retreat

Saint Charles MO

0.11 mi from Historic Main Street

$303 nightly

$334 total

Sep 7 - Sep 8

Total with taxes and fees

Stay at this apartment in St. Charles. Enjoy free WiFi, an in-room coffeemaker, and air conditioning. Popular attractions Ameristar Casino St. Charles and Hollywood Casino Amphitheatre are located nearby.

Kitchen

Pet friendly

Driftwood Den | Boho 2BR | Dog-Friendly

Saint Charles MO

0.11 mi from Historic Main Street

$303 nightly

$334 total

Sep 7 - Sep 8

Total with taxes and fees

Kitchen

Pet friendly

Stylish 2BR Retreat - Concrete & Canopy

Saint Charles MO

0.11 mi from Historic Main Street

$314 nightly

$346 total

Sep 7 - Sep 8

Total with taxes and fees

Kitchen

Pet friendly

Riverwood Retreat | Main Street 2BR

Saint Charles MO

0.11 mi from Historic Main Street

$299 nightly

$330 total

Sep 30 - Oct 1

Total with taxes and fees

Stay at this apartment in St. Charles. Enjoy free WiFi and air conditioning. Popular attractions Ameristar Casino St. Charles and Hollywood Casino Amphitheatre are located nearby.

Kitchen

Pet friendly

Hearth & Harvest | Historic St. Charles 2BR

Saint Charles MO

0.11 mi from Historic Main Street

$301 nightly

$331 total

Sep 7 - Sep 8

Total with taxes and fees

Kitchen

Pet friendly

The Foundry Flat | Industrial-Inspired 2-Bedroom

Saint Charles MO

0.11 mi from Historic Main Street

$307 nightly

$338 total

Sep 7 - Sep 8

Total with taxes and fees

Kitchen

Pet friendly

The St. Charles Guest House, lovely historic home, fun for families and groups

St. Charles MO

0.11 mi from Historic Main Street

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This vacation home features a water park and laundry facilities.

Kitchen

Washer

1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!

St. Charles MO

0.17 mi from Historic Main Street

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This cottage features a water park and free WiFi in public areas.

Kitchen

Free WiFi

Country Inn & Suites by Radisson, St. Charles Historic District

1190 S Main St St. Charles MO

Free Cancellation

0.62 mi from Historic Main Street

$136 nightly

$156 total

Oct 4 - Oct 5

Total with taxes and fees

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.

Pool

Breakfast included

Ameristar Casino Resort and Spa

1 Ameristar Blvd St. Charles MO

Free Cancellation

Reserve now, pay when you stay

0.89 mi from Historic Main Street

$182 nightly

$213 total

Sep 7 - Sep 8

Total with taxes and fees

This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and outdoor pool, and unwind with a drink at the poolside bar.

Pool

Hot Tub

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Historic Main Street hotels essential information

Accommodation	509 hotels
Lowest Price	$156
Highest Price	$346
Popular hotels	Ameristar Casino Resort and Spa, The St. Charles Guest House, lovely historic home, fun for families and groups, Country Inn & Suites by Radisson, St. Charles Historic District, 1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo., The Rustic Revival \| Charming 2BR Retreat, Driftwood Den \| Boho 2BR \| Dog-Friendly, Stylish 2BR Retreat - Concrete & Canopy, 1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!, Luxurious, spa-like retreat steps from Main St., Riverwood Retreat \| Main Street 2BR, Hearth & Harvest \| Historic St. Charles 2BR, The Foundry Flat \| Industrial-Inspired 2-Bedroom

Recent Historic Main Street hotel reviews by fellow wanderers

Country Inn & Suites by Radisson, St. Charles Historic District

5 out of 5

Posted 2 days ago

Travelocity Verified Review

"We enjoyed our stay near the old city streets and shops. Our hotel was by far the best in the St. Louis/St. Charles area. We had a wonderful breakfast and a swim in the pool! The room was big with a great view."

A verified traveler stayed at Country Inn & Suites by Radisson, St. Charles Historic District

1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.

5 out of 5

Posted 3 weeks ago

Travelocity Verified Review

"The home was very inviting! All of the hosts extra touches so appreciated (coffee pods, snacks, etc). Beds were comfortable and all necessities were available. A wonderful stay! We will definitely return."

A verified traveler stayed at 1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.