Photo by Geraldine Soh
Book a hotel near Historic Main Street, St. Charles Historic District
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Top hotels close to Historic Main Street

HUGE 2 bedroom unit on Main Street
0.09 mi from Historic Main Street
This apartment features laundry facilities.
Kitchen
Washer

1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.
0.1 mi from Historic Main Street
A hot tub is featured at this vacation home, along with a garden and laundry facilities. Barbecue grills are provided for your convenience.
Hot Tub
Kitchen

Luxurious, spa-like couples retreat steps from Main Street in St. Charles!
0.11 mi from Historic Main Street
A water park and a hot tub are featured at this smoke-free vacation home. Enjoy the sauna and conveniences like a garden and laundry facilities.
Hot Tub
Kitchen

The St. Charles Guest House, lovely historic home, fun for families and groups
0.11 mi from Historic Main Street
This vacation home features a water park and laundry facilities.
Kitchen
Washer

The Hare Suite at Divine Otter
0.15 mi from Historic Main Street
Stay at this aparthotel in St. Charles. Enjoy free WiFi, patios, and an in-room coffeemaker. Popular attractions Ameristar Casino St. Charles and Hollywood Casino Amphitheatre are located nearby.
Kitchen
Free WiFi

The Otter Suite at Divine Otter
0.15 mi from Historic Main Street
Stay at this aparthotel in St. Charles. Enjoy free WiFi, an in-room coffeemaker, and air conditioning. Popular attractions Ameristar Casino St. Charles and Hollywood Casino Amphitheatre are located nearby.
Kitchen
Free WiFi

The Wild West Getaway- 204-1
0.16 mi from Historic Main Street
This apartment features laundry facilities.
Kitchen
Washer

1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!
0.17 mi from Historic Main Street
This cottage features a water park and free WiFi in public areas.
Kitchen
Free WiFi

Charming Cottage on Main St. in Historic St. Charles! Jetted Tub, 2 Fireplaces!!
0.17 mi from Historic Main Street
This vacation home features a water park, free WiFi in public areas, and a garden. Laundry facilities are provided for your convenience.
Kitchen
Washer

Country Inn & Suites by Radisson, St. Charles Historic District
1190 S Main St, St. Charles, MO
Free Cancellation
0.62 mi from Historic Main Street
$114 nightly
The price is $131 total per night
$131 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Pool
Breakfast included

Ameristar Casino Resort and Spa
1 Ameristar Blvd, St. Charles, MO
Free Cancellation
Reserve now, pay when you stay
0.89 mi from Historic Main Street
$192 nightly
The price is $224 total per night
$224 total
Oct 5 - Oct 6
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside bar.
Pool
Hot Tub

Best Western Plus The Charles Hotel
1425 South 5th Street, St. Charles, MO
Free Cancellation
Reserve now, pay when you stay
0.9 mi from Historic Main Street
$93 nightly
The price is $107 total per night
$107 total
Oct 12 - Oct 13
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Pool
Breakfast included
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See all available properties in Historic Main Street
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Historic Main Street hotels essential information
Accommodation | 465 hotels |
---|---|
Lowest Price | $107 |
Highest Price | $224 |
Popular hotels | Ameristar Casino Resort and Spa, The St. Charles Guest House, lovely historic home, fun for families and groups, Country Inn & Suites by Radisson, St. Charles Historic District, 1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!, 1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo., Luxurious, spa-like couples retreat steps from Main Street in St. Charles!, The Hare Suite at Divine Otter, HUGE 2 bedroom unit on Main Street, The Otter Suite at Divine Otter, Best Western Plus The Charles Hotel, The Wild West Getaway- 204-1, Charming Cottage on Main St. in Historic St. Charles! Jetted Tub, 2 Fireplaces!! |
Recent Historic Main Street hotel reviews by fellow wanderers

Ameristar Casino Resort and Spa
5 out of 5
Posted 4 days ago
Travelocity Verified Review
"Clean room "
A verified traveler stayed at Ameristar Casino Resort and Spa
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