Exclusive Main Street Cultural District Vacation Deals

Main Street Cultural District vacation package deals

Price found within the past 48 hours. Click for updated prices.
AmericInn by Wyndham Ankeny/Des Moines

AmericInn by Wyndham Ankeny/Des Moines

3 out of 5
Price was $484, price is now $409 per person
$409
per person
Feb 11 - Feb 15
found 1 day ago
Roundtrip flight included
Phoenix (PHX) to Des Moines (DSM)
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Comfort Inn Altoona-Des Moines

Comfort Inn Altoona-Des Moines

2.5 out of 5
Price was $621, price is now $581 per person
$581
per person
Feb 6 - Feb 10
found 21 hours ago
Roundtrip non-stop flight included
Oakland (OAK) to Des Moines (DSM)
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business center. Enjoy the gym and conveniences like a 24-hour front desk and laundry facilities.
Microtel Inn & Suites by Wyndham Urbandale/Des Moines

Microtel Inn & Suites by Wyndham Urbandale/Des Moines

2 out of 5
Price was $592, price is now $555 per person
$555
per person
Feb 6 - Feb 10
found 20 hours ago
Roundtrip non-stop flight included
Oakland (OAK) to Des Moines (DSM)
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the 2 conference rooms, business center, and express check-out. Enjoy the 24-hour gym and conveniences like a 24-hour front desk and laundry facilities.
Baymont by Wyndham Des Moines North

Baymont by Wyndham Des Moines North

2.5 out of 5
Price was $568, price is now $539 per person
$539
per person
Feb 6 - Feb 10
found 21 hours ago
Roundtrip non-stop flight included
Oakland (OAK) to Des Moines (DSM)
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. Guests will appreciate freebies like continental breakfast and free self parking.
La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA

La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA

3 out of 5
Price was $505, price is now $481 per person
$481
per person
Feb 11 - Feb 15
found 1 day ago
Roundtrip flight included
Phoenix (PHX) to Des Moines (DSM)
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Courtyard by Marriott Des Moines West Clive

Courtyard by Marriott Des Moines West Clive

3 out of 5
Price was $505, price is now $483 per person
$483
per person
Feb 11 - Feb 15
found 1 day ago
Roundtrip flight included
Phoenix (PHX) to Des Moines (DSM)
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the gym and perks like free self parking.

Frequently asked questions

How much are vacation packages to Main Street Cultural District?
Let Travelocity take the worry out of arranging your next big trip to Main Street Cultural District. Book our convenient $409 package deal and save both time and money. With your hotel and flights locked in, you can focus on the fun parts of your getaway — like crossing off those famous attractions!
Where can I get the best vacation package deals for Main Street Cultural District?
Travelocity is here to help you snag an unbeatable Main Street Cultural District package deal. With as many as 400 partner airlines and 1,000,000 properties around the world, there's no doubt you'll find the perfect combination.
Why should I purchase my Main Street Cultural District vacation package with Travelocity?
Because you'll never wander alone if you book your trip through us, and we offer round-the-clock customer support and excellent service to boot. Add to that our Price Match Guarantee and countless destinations to select from. We're here to make your vacation as unforgettable as possible.

Top Main Street Cultural District hotel deals

Gateway Hotel and Conference Center at Iowa State University

Gateway Hotel and Conference Center at Iowa State University

3 out of 5
2100 Green Hills Drive Ames IA
$76 nightly
The price is $86 total per night
$86 total
Dec 28 - Dec 29
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference space. Enjoy the gym and perks like free self parking.
Pool
Hot Tub
Comfort Inn and Suites Ames near ISU Campus

Comfort Inn and Suites Ames near ISU Campus

2.5 out of 5
603 South 16th Street Ames IA
Free Cancellation
Reserve now, pay when you stay
$82 nightly
The price is $91 total per night
$91 total
Jan 23 - Jan 24, 2026
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like full breakfast and free self parking.
Pool
Breakfast included
Country Inn & Suites by Radisson, Ames, IA

Country Inn & Suites by Radisson, Ames, IA

2.5 out of 5
2605 Se 16th St Ames IA
Free Cancellation
$77 nightly
The price is $87 total per night
$87 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and free perks like continental breakfast and free self parking.
Pool
Hot Tub
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.