Explore top 2025 5 Star Hotels in Cyclades Islands

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Top Cyclades Islands 5 Star hotels

Santo Pure Oia Suites & Villas

Santo Pure Oia Suites & Villas

5 out of 5
Oia, Santorini
$336 nightly
The price is $399 total per night from Oct 5 to Oct 6
$399 total
Oct 5 - Oct 6
Total with taxes and fees
A full-service spa, 6 outdoor pools, and a hot tub are all featured at this luxury hotel. Traveling on business? Take advantage of the free WiFi in public areas, ...
Santo Pure Oia Suites & Villas
Myconian Korali

Myconian Korali

5 out of 5
Main Street, Mykonos Town, Mykonos
Fully refundableReserve now, pay when you stay
$250 nightly
The price is $302 total per night from Oct 6 to Oct 7
$302 total
Oct 6 - Oct 7
Total with taxes and fees
A full-service spa and a restaurant are featured at this luxury hotel. Families will appreciate the onsite laundry facilities and in-room childcare. Enjoy the ...
Myconian Korali
Myconian Ambassador Hotel Relais & Chateaux

Myconian Ambassador Hotel Relais & Chateaux

5 out of 5
Platis Gialos, Mykonos, Mykonos Island
Fully refundableReserve now, pay when you stay
$287 nightly
The price is $345 total per night from Sep 28 to Sep 29
$345 total
Sep 28 - Sep 29
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the free WiFi in public areas, ...
Myconian Ambassador Hotel Relais & Chateaux
NOŪS Santorini

NOŪS Santorini

5 out of 5
Mesaria, Santorini, Santorini Island
$283 nightly
The price is $339 total per night from Oct 5 to Oct 6
$339 total
Oct 5 - Oct 6
Total with taxes and fees
A full-service spa, 2 restaurants, and a gym are all featured at this luxury resort. Enjoy the steam room and free perks like full breakfast and free self parking. ...
NOŪS Santorini
CAVO TAGOO MYKONOS

CAVO TAGOO MYKONOS

5 out of 5
TAGOO MYKONOS, Mykonos
$593 nightly
The price is $693 total per night from Oct 2 to Oct 3
$693 total
Oct 2 - Oct 3
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the gym and free perks like buffet breakfast and valet parking. Enjoy the sauna and ...
CAVO TAGOO MYKONOS
Antoperla Luxury Hotel & Spa

Antoperla Luxury Hotel & Spa

5 out of 5
Perissa, Santorini
A full-service spa, a gym, and a restaurant are all featured at this luxury hotel. Enjoy the outdoor pool and free perks like buffet breakfast and free self ...
Antoperla Luxury Hotel & Spa
Palladium Hotel

Palladium Hotel

5 out of 5
Plati Yialos, Mykonos, Mykonos Island
Fully refundableReserve now, pay when you stay
$316 nightly
The price is $377 total per night from Sep 10 to Sep 11
$377 total
Sep 10 - Sep 11
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities and babysitting. ...
Palladium Hotel
Andronis Arcadia Hotel

Andronis Arcadia Hotel

5 out of 5
Oia, Santorini, Santorini Island
$499 nightly
The price is $584 total per night from Oct 6 to Oct 7
$584 total
Oct 6 - Oct 7
Total with taxes and fees
A full-service spa, 2 restaurants, and a gym are all featured at this luxury hotel. Relax with a drink at one of the 2 poolside bars and enjoy free perks like ...
Andronis Arcadia Hotel
Saint John Hotel Villas & Spa

Saint John Hotel Villas & Spa

5 out of 5
Aghios Ioannis Beach, Aghios Ioannis, Mykonos, Mykonos Island
$139 nightly
The price is $176 total per night from Oct 2 to Oct 3
$176 total
Oct 2 - Oct 3
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and 3 restaurants. Enjoy the indoor pool and perks like free valet parking and free WiFi. Enjoy ...
Saint John Hotel Villas & Spa
The Majestic Hotel

The Majestic Hotel

5 out of 5
Fira, Santorini, Santorini Island
$227 nightly
The price is $275 total per night from Sep 24 to Sep 25
$275 total
Sep 24 - Sep 25
Total with taxes and fees
This smoke-free hotel features 2 restaurants, a bar/lounge, and a gym. There's fun for all ages with a children's pool and a playground, and families will appreciate ...
The Majestic Hotel
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Cyclades Islands Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Cyclades Islands to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Cyclades Islands 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Cyclades Islands before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.