Explore top 2025 4 Star Hotels in Sanford

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Top Sanford 4 Star hotels

21c Museum Hotel Durham

21c Museum Hotel Durham

4 out of 5
111 North Corcoran Street, Durham, NC
Fully refundableReserve now, pay when you stay
$184 nightly
The price is $209 total per night from Oct 12 to Oct 13
$209 total
Oct 12 - Oct 13
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the sauna and perks like free WiFi. Valet parking, a 24-hour business center, and dry ...
8.2/10 Very Good! (1,001 reviews)
"The hotel is in a very good location. Staff was excellent. I loved the art on display. It was an interesting touch. We will definitely stay there again."

Reviewed on Sep 30, 2025

Opens in a new window21c Museum Hotel Durham
DoubleTree Suites by Hilton Raleigh - Durham

DoubleTree Suites by Hilton Raleigh - Durham

4 out of 5
2515 Meridian Pkwy, Durham, NC
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $111 total per night from Oct 12 to Oct 13
$111 total
Oct 12 - Oct 13
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like free WiFi and a free airport shuttle. There's an outdoor ...
8.8/10 Excellent! (1,003 reviews)
"Nice getaway"

Reviewed on Oct 3, 2025

Opens in a new windowDoubleTree Suites by Hilton Raleigh - Durham
JB Duke Hotel

JB Duke Hotel

4 out of 5
230 Science Drive, Durham, NC
Fully refundableReserve now, pay when you stay
$201 nightly
The price is $228 total per night from Oct 15 to Oct 16
$228 total
Oct 15 - Oct 16
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Guests will appreciate free perks like free self parking and WiFi in public areas. A business center, ...
9.4/10 Exceptional! (506 reviews)
"Great location to Duke games!"

Reviewed on Sep 23, 2025

Opens in a new windowJB Duke Hotel
The Durham Hotel

The Durham Hotel

4 out of 5
315 East Chapel Hill Street, Durham, NC
Fully refundableReserve now, pay when you stay
$186 nightly
The price is $211 total per night from Oct 9 to Oct 10
$211 total
Oct 9 - Oct 10
Total with taxes and fees
The hotel's 24-hour gym, a rooftop terrace, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the business center ...
8.8/10 Excellent! (614 reviews)
"Love the decor. A wonderful surprise."

Reviewed on Sep 14, 2025

Opens in a new windowThe Durham Hotel
The Westin Raleigh-Durham Airport

The Westin Raleigh-Durham Airport

4 out of 5
3931 MACAW STREET, Raleigh, NC
Fully refundableReserve now, pay when you stay
$215 nightly
The price is $244 total per night from Oct 26 to Oct 27
$244 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free ...
9.4/10 Exceptional! (259 reviews)
"Really nice hotel, clean and refreshing, Starbucks in main lobby, big parking lot and lots of food options near by! Would stay there again"

Reviewed on Sep 25, 2025

Opens in a new windowThe Westin Raleigh-Durham Airport
Washington Duke Inn & Golf Club

Washington Duke Inn & Golf Club

4 out of 5
3001 Cameron Blvd, Durham, NC
Fully refundableReserve now, pay when you stay
$235 nightly
The price is $267 total per night from Oct 29 to Oct 30
$267 total
Oct 29 - Oct 30
Total with taxes and fees
A golf course, 3 restaurants, and an indoor pool are all featured at this boutique hotel. Family-friendly amenities include an arcade/game room and in-room childcare. ...
9.4/10 Exceptional! (1,000 reviews)
"Washington Duke is always nice even during construction of improvements"

Reviewed on Sep 14, 2025

Opens in a new windowWashington Duke Inn & Golf Club
DoubleTree Raleigh Durham Airport at Research Triangle Park

DoubleTree Raleigh Durham Airport at Research Triangle Park

4 out of 5
4810 Page Creek Ln, Durham, NC
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $115 total per night from Oct 31 to Nov 1
$115 total
Oct 31 - Nov 1
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9/10 Wonderful! (999 reviews)
"Very good"

Reviewed on Sep 25, 2025

Opens in a new windowDoubleTree Raleigh Durham Airport at Research Triangle Park
The Mayton

The Mayton

4 out of 5
301 S Academy St, Cary, NC
$177 nightly
The price is $201 total per night from Oct 12 to Oct 13
$201 total
Oct 12 - Oct 13
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 3 conference rooms, free WiFi in public areas, and laundry ...
9.4/10 Exceptional! (696 reviews)
"Good"

Reviewed on Oct 1, 2025

Opens in a new windowThe Mayton
Rizzo Center, a Destination by Hyatt Hotel

Rizzo Center, a Destination by Hyatt Hotel

4 out of 5
150 DuBose Home Lane, Chapel Hill, NC
Fully refundableReserve now, pay when you stay
$238 nightly
The price is $270 total per night from Oct 15 to Oct 16
$270 total
Oct 15 - Oct 16
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9.6/10 Exceptional! (1,000 reviews)
"I really enjoyed this property. Each floor has an area with snacks in a refrigerator like sodas and ice cream and popcorn. We stayed during a not very busy time, but I bet this place would be amazing during a football or basketball game."

Reviewed on Sep 4, 2025

Opens in a new windowRizzo Center, a Destination by Hyatt Hotel
The Carolina Inn, a Destination by Hyatt Hotel

The Carolina Inn, a Destination by Hyatt Hotel

4.5 out of 5
211 Pittsboro Street, Chapel Hill, NC
Fully refundableReserve now, pay when you stay
$381 nightly
The price is $432 total per night from Oct 19 to Oct 20
$432 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9.6/10 Exceptional! (1,001 reviews)
"Lovely old world Southern charm. I’ll be back!"

Reviewed on Sep 30, 2025

Opens in a new windowThe Carolina Inn, a Destination by Hyatt Hotel
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4 Star Hotels Sanford

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Sanford 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Sanford will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Sanford, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Sanford hotel reviews by fellow wanderers

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