Explore 21 Luxury Hotels in Syracuse

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Best Luxury Hotels in Syracuse

Grand Hotel Des Ètrangers - The Leading Hotels of the World

Passeggio Adorno 10/12 Syracuse SR

Fully refundableReserve now, pay when you stay

$569 nightly

$638 total

May 2 - May 3

Total with taxes and fees

A full-service spa, a gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public areas, ...

9.6/10 Exceptional! (73 reviews)

Great hotel and saff

Reviewed on Oct 20, 2025

Algila' Ortigia Charme Hotel

Via Vittorio Veneto 93 Syracuse SR

Fully refundableReserve now, pay when you stay

$273 nightly

$312 total

Apr 6 - Apr 7

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. Families will appreciate the onsite laundry facilities and in-room childcare. Guests will appreciate ...

9.6/10 Exceptional! (937 reviews)

The breakfast buffet was good and restaurant at dinner was very nice. A view of the sea from my room was wonderful. Front desk were helpful.

Reviewed on Mar 27, 2026

Hotel Parco delle Fontane

Viale Scala Greca, 325 Syracuse SR

Fully refundableReserve now, pay when you stay

$101 nightly

$115 total

Apr 12 - Apr 13

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

9.2/10 Wonderful! (286 reviews)

Courteous staff

Reviewed on Jan 27, 2026

Grand Hotel Ortigia Siracusa

Viale Mazzini, 12 Syracuse SR

Fully refundableReserve now, pay when you stay

$253 nightly

$290 total

Apr 9 - Apr 10

Total with taxes and fees

This hotel features a restaurant, a rooftop terrace, and a bar/lounge. Take the beach shuttle and relax with sun loungers and beach umbrellas. WiFi in public ...

9/10 Wonderful! (584 reviews)

Absolutely lovely.

Reviewed on Mar 30, 2026

Minareto

Via del Faro Massolivieri 26 Syracuse SR

Fully refundableReserve now, pay when you stay

$350 nightly

$397 total

May 1 - May 2

Total with taxes and fees

This luxury hotel features a private beach, a full-service spa, and 2 restaurants. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Families ...

8.8/10 Excellent! (267 reviews)

Winderfull views but the staff isn’t so supportive!

Reviewed on Nov 9, 2025

Grande Albergo Alfeo

Via Nino Bixio 5 Syracuse SR

Fully refundableReserve now, pay when you stay

$113 nightly

$129 total

Apr 9 - Apr 10

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...

8.6/10 Excellent! (656 reviews)

Good front desk staff, welcoming breakfast staff, clean room and good area for walking to attractions.

Reviewed on Dec 2, 2025

Eureka Palace Hotel Spa Resort

Strada Spinagallo 50 Syracuse SR

Fully refundableReserve now, pay when you stay

$97 nightly

$111 total

Apr 6 - Apr 7

Total with taxes and fees

A full-service spa, 4 outdoor tennis courts, and an indoor pool are all featured at this smoke-free hotel. Relax with a drink at one of the 3 bars/lounges and ...

8/10 Very Good! (327 reviews)

Reviewed on Oct 20, 2025

Hotel Livingston Siracusa

Via Nizza, 17 Syracuse SR

A bar/lounge and a 24-hour front desk are featured at this hotel, along with valet parking. Guests will appreciate free perks like full breakfast and WiFi in ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Syracuse

Borgo Pantano

Traversa Fontana Mortella, 13 int. 4 Syracuse SR

$126 nightly

$144 total

Apr 7 - Apr 8

Total with taxes and fees

9.8/10 Exceptional! (276 reviews)

5 star hotels in Syracuse

Grand Hotel Des Ètrangers - The Leading Hotels of the World

Passeggio Adorno 10/12 Syracuse SR

$569 nightly

$638 total

May 2 - May 3

Total with taxes and fees

9.6/10 Exceptional! (73 reviews)

Syracuse Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Syracuse luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Syracuse to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Syracuse will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Syracuse, and plan your next opulent escape.

Syracuse hotels essential information

Accommodation	2,141 hotels
Lowest Price	$110
Highest Price	$638
Popular hotels	Grand Hotel Des Ètrangers - The Leading Hotels of the World, Grand Hotel Ortigia Siracusa, Minareto, Eureka Palace Hotel Spa Resort, Algila' Ortigia Charme Hotel, Hotel Livingston Siracusa, Hotel Parco delle Fontane, Grande Albergo Alfeo