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Santa Cruz
Vacations
Top Santa Cruz hotels deals

Ibis Santa Cruz DE LA Sierra
AVENIDA CRISTOBAL DE MENDOZA, Santa Cruz
$43 nightly
The price is $43 total per night
$43 total
Aug 26 - Aug 27
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and airport shuttle. Free self parking, a coffee shop, and a snack bar/deli are also offered.

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Ave. San Martin, #455, Santa Cruz
$125 nightly
The price is $125 total per night
$125 total
Aug 18 - Aug 19
A full-service spa, 2 restaurants, and a hot tub are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.
Pool
Hot Tub

Marriott Santa Cruz de la Sierra Hotel
4to Anillo Entre Radial 23, At Calle Las Ramblas, Santa Cruz, Santa Cruz
$119 nightly
The price is $119 total per night
$119 total
Aug 22 - Aug 23
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and perks like free self parking.
Pool
Spa

Camino Real Hotel
Av. San Martín y 4to. Anillo, Equipetrol Norte, Santa Cruz
$140 nightly
The price is $140 total per night
$140 total
Sep 1 - Sep 2
A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. There's fun for all ages with a children's pool and a waterslide, and babysitting is an added bonus. Unwind with a drink at one of the 2 bars/lounges and enjoy free perks like buffet breakfast and WiFi in public areas.
Pool
Hot Tub

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
San Martin Avenue Esq Street E - E, Santa Cruz
$75 nightly
The price is $75 total per night
$75 total
Aug 15 - Aug 16
This hotel features a restaurant, a gym, and a bar/lounge. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A business center, a garden, and a snack bar/deli are also on offer.
Breakfast included
Parking included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit

Plaza 24 de Septiembre
Learn about the local history of Santa Cruz when you spend time at Plaza 24 de Septiembre. While in the area, you can find time to visit its shops.

San Lorenzo Cathedral
Learn about the local history of Santa Cruz when you spend time at San Lorenzo Cathedral. While in the area, you can find time to visit its shops.
Ventura Mall
During your visit to Santa Cruz, you can find the perfect gifts to bring home at Ventura Mall. Make some time to visit the cathedral while you're in the area.
Photos of local treasures
Browse Santa Cruz vacation photos for more inspiration





Frequently asked questions
Where to stay in Santa Cruz: Best areas for travelers
- WarnesWarnes: Stay at the Los Jazmines Hotel Resort or the Terramia Resort and you'll be well taken care of. While you'll find a lot of awesome sights here, Warnes Plaza is one thing you can't miss. Make sure it's high on your sightseeing list!
- Samaipata: Plan ahead so you can see all of this bustling destination. Fort Samaipata, Zoologico el refugio and Zoo el Refugio should be at the top of your bucket list. If excellent service and a good night's sleep are your main priorities, the Hotel Casablanca, the Hotel Casablanca Samaipata and the El Pueblito Hotel Boutique are stays to check out.
- San Jose de Chiquitos: Santa Cruz is packed with popular sights, like Church of the Jesuit Mission of St. Joseph. Spend some time exploring this unique attraction before returning to the comfy surrounds of the Hotel Misiones de Chiquitos. Looking for more choices around town? The La Villa Chiquitana is also well-frequented by visitors.
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