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Top hotels close to Museum of Life and Science

Guest House with private Gate Near Downtown Durham Peaceful 2-bedroom 2 Bathroom
Durham NC
0.31 mi from Museum of Life and Science
$290 nightly
The price is $329 total per night
$329 total
May 11 - May 12
Total with taxes and fees
This vacation home features an outdoor pool and a hot tub. A garden, laundry facilities, and barbecue grills are also on offer.

Bull City Bungalow Walk to Ninth St Near Duke
Durham NC
0.62 mi from Museum of Life and Science
$374 nightly
The price is $425 total per night
$425 total
May 11 - May 12
Total with taxes and fees
A garden is available at this vacation home.

Everything within 1 mile
Durham NC
0.72 mi from Museum of Life and Science
This vacation home includes a garden and laundry facilities.

Curated Duke Med Retreat • Mins to DPAC/Downtown • Espresso, Eco+, Fire Pit
Durham NC
0.74 mi from Museum of Life and Science
A gym is featured at this vacation home, along with laundry facilities and concierge services. Barbecue grills are provided for your convenience.

Hampton Inn & Suites Durham/North I-85
1542 North Gregson Street Durham NC
Free Cancellation
Reserve now, pay when you stay
0.84 mi from Museum of Life and Science
$118 nightly
The price is $134 total per night
$134 total
May 24 - May 25
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy freebies like buffet breakfast and an area shuttle

Drexall Haven - Stylish + Peaceful Stay
Durham NC
1.08 mi from Museum of Life and Science
This vacation home features laundry facilities.

Tiny Home a fantastic Location close to 9th Street!
Durham NC
1.1 mi from Museum of Life and Science
This vacation home includes a garden and laundry facilities.

Red Roof Inn Durham - Duke Univ Medical Center
1915 N Pointe Drive Durham NC
Free Cancellation
Reserve now, pay when you stay
1.34 mi from Museum of Life and Science
$64 nightly
The price is $73 total per night
$73 total
May 13 - May 14
Total with taxes and fees
Free self parking is available and the hotel's front desk is staffed around-the-clock. WiFi in public areas is free. A safe deposit box is also provided.

Holiday Inn Express Durham by IHG
2516 Guess Rd Durham NC
Free Cancellation
1.35 mi from Museum of Life and Science
$110 nightly
The price is $125 total per night
$125 total
May 31 - Jun 1
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free self parking, and a free area shuttle. Traveling on business? Take advantage of the business center and free WiFi in public areas. There's an outdoor pool on site, and laundry facilities and free newspapers are also offered.

Comfort Inn & Suites Durham near Duke University
1816 Hillandale Rd Durham NC
Free Cancellation
1.99 mi from Museum of Life and Science
$95 nightly
The price is $108 total per night
$108 total
May 25 - May 26
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like on-the-go breakfast and free self parking.

Courtyard Durham Near Duke University/Downtown
1815 Front St Durham NC
Free Cancellation
Reserve now, pay when you stay
2.11 mi from Museum of Life and Science
$93 nightly
The price is $105 total per night
$105 total
May 15 - May 16
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the seasonal outdoor pool and perks like free self parking and a free area shuttle.

21c Museum Hotel Durham
111 North Corcoran Street Durham NC
Free Cancellation
Reserve now, pay when you stay
2.32 mi from Museum of Life and Science
$165 nightly
The price is $187 total per night
$187 total
May 31 - Jun 1
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the sauna and perks like free WiFi. Valet parking, a 24-hour business center, and dry cleaning are also offered.
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See all available properties in Museum of Life and Science
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Museum of Life and Science hotels essential information
Accommodation | 1,028 hotels |
|---|---|
Lowest Price | $73 |
Highest Price | $425 |
Popular hotels | Holiday Inn Express Durham by IHG, Hampton Inn & Suites Durham/North I-85, Courtyard Durham Near Duke University/Downtown, Comfort Inn & Suites Durham near Duke University, Guest House with private Gate Near Downtown Durham Peaceful 2-bedroom 2 Bathroom, Bull City Bungalow Walk to Ninth St Near Duke, Everything within 1 mile, Curated Duke Med Retreat • Mins to DPAC/Downtown • Espresso, Eco+, Fire Pit, Red Roof Inn Durham - Duke Univ Medical Center, 21c Museum Hotel Durham, Drexall Haven - Stylish + Peaceful Stay, Tiny Home a fantastic Location close to 9th Street! |
Recent Museum of Life and Science hotel reviews by fellow wanderers

21c Museum Hotel Durham
2 out of 5
Posted 21 hours ago
Travelocity Verified Review
"The hotel doesn’t live up to its photos. The elevators were noticeably dirty, our room smelled like cigarette smoke, and the air conditioning wasn’t working when we arrived.
We called the front desk and spoke with Melanie, who said the hotel was fully booked so we couldn’t switch rooms, but that an engineer would come up to fix the AC. Forty minutes passed and no one showed up, so we called again. This time we were told the engineer had already reset the thermostat remotely, but the room was still warm and stayed that way all night. We also noticed rooms showing as available online while being told the hotel was at capacity, which was confusing.
By then it was past 10:30pm and we were tired, so we let it go. Not a great night’s sleep.
The one highlight was the valet team, who were genuinely kind and went out of their way to help."
A verified traveler stayed at 21c Museum Hotel Durham
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