Find & Compare 21 Adults-Only Hotels & Resorts in Key West With Rates at from $315

Name: The Southernmost Inn - Adults Only
Price range: $460 total
Rating: 8.2

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Top Adults Only Resorts in Key West Historic District

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

1118 Fleming St Key West FL

$368 nightly

$414 total

Apr 1 - Apr 2

Total with taxes and fees

This hotel features an outdoor pool and a hot tub. Guests will appreciate free perks like continental breakfast and WiFi in public areas. A business center, ...

9.8/10 Exceptional! (142 reviews)

Staff very courteous and friendly, public spaces lovely.

Reviewed on Feb 8, 2026

Duval House

815 Duval St Key West FL

$401 nightly

$448 total

Mar 15 - Mar 16

Total with taxes and fees

This bed & breakfast features a terrace, concierge services, and self parking. A garden, a picnic area, and express check-in are also on offer.

9.4/10 Exceptional! (1,013 reviews)

Ideal location. Fun, friendly and knowledgeable staff. Nice breakfast included each morning. Quiet and relaxing place to stay

Reviewed on Mar 11, 2026

Paradise Inn Key West - Adults Only

819 Simonton Street Key West FL

Fully refundableReserve now, pay when you stay

$417 nightly

$469 total

Apr 5 - Apr 6

Total with taxes and fees

This hotel features an outdoor pool and a hot tub. Enjoy the free continental breakfast each morning. Self parking, a terrace, and a garden are also ...

9.2/10 Wonderful! (1,012 reviews)

Close to everything

Reviewed on Mar 11, 2026

Ridley House - Key West Historic Inns

601 Caroline St Key West FL

Fully refundableReserve now, pay when you stay

$443 nightly

$499 total

Apr 5 - Apr 6

Total with taxes and fees

An outdoor pool is featured at this hotel, along with free WiFi in public areas and luggage storage. Enjoy the free buffet breakfast each morning. Concierge ...

9.2/10 Wonderful! (886 reviews)

Nice little quaint place, great breakfast, the roosters are something to be desired tho, crow all hours of the night

Reviewed on Mar 9, 2026

Heron House - Adult Only

512 Simonton St Key West FL

$322 nightly

$362 total

Mar 12 - Mar 13

Total with taxes and fees

This bed & breakfast features an outdoor pool and a rooftop terrace. Guests will appreciate free perks like continental breakfast and WiFi in public areas. A ...

9/10 Wonderful! (1,152 reviews)

Old. Pool but cold this time of year. Good location. Not a lot of staff. Affordable. Served our purpose

Reviewed on Mar 8, 2026

Heron House Court - Adult Only

412 Frances St Key West FL

$280 nightly

$315 total

Mar 12 - Mar 13

Total with taxes and fees

This guesthouse features an outdoor pool and a rooftop terrace. WiFi in public areas is free. A terrace, a garden, and luggage storage are also on offer.

9/10 Wonderful! (1,008 reviews)

Roman is absolutely accommodating and he’ll bend over backwards to make sure that you’re happy. I highly recommend this laid-back cool vibe hotel.

Reviewed on Mar 11, 2026

The Cabana Inn Key West - Adults Only

413 Applerouth Lane Key West FL

$326 nightly

$367 total

Mar 24 - Mar 25

Total with taxes and fees

This guesthouse features an outdoor pool and a hot tub. Enjoy the free continental breakfast each morning. Self parking, a terrace, and a garden are also ...

8.8/10 Excellent! (1,022 reviews)

Location is great for activities. Staff was friendly. Even though Rosters are part of Key West, they are getting out of control with crowing all night out your bedroom window (take ear plugs). There is a hidden hotel amenity fee of $39.99 per night for a couple. I did double-check Expedia advertisement ...

Reviewed on Mar 8, 2026

The Southernmost Inn - Adults Only

525 United Street Key West FL

Fully refundableReserve now, pay when you stay

$409 nightly

$460 total

Mar 12 - Mar 13

Total with taxes and fees

This hotel's 2 outdoor pools and hot tub are among the featured amenities. Enjoy the free continental breakfast each morning. Self parking, a coffee shop, and ...

8.2/10 Very Good! (1,289 reviews)

The pool is well kept. The staff was very friendly and competent.

Reviewed on Mar 11, 2026

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.