Explore 10 Luxury Hotels in Downtown Santiago

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Best Luxury Hotels in Downtown Santiago

The Singular Santiago

The Singular Santiago

Merced 294, Santiago, Region Metropolitana
Fully refundableReserve now, pay when you stay
$250 nightly
The price is $250 total per night from Oct 11 to Oct 12
$250 total
Oct 11 - Oct 12
A full-service spa, 2 restaurants, and A 24-hour gym are all featured at this smoke-free hotel. Enjoy the seasonal outdoor pool and free perks like cooked-to-order ...
9.4/10 Exceptional! (649 reviews)

Reviewed on Sep 15, 2025

Opens in a new windowThe Singular Santiago
Casa Bueras Boutique Hotel

Casa Bueras Boutique Hotel

Coronel Santiago Bueras 188, Santiago, Region Metropolitana
Fully refundableReserve now, pay when you stay
$126 nightly
The price is $126 total per night from Oct 14 to Oct 15
$126 total
Oct 14 - Oct 15
This hotel features an outdoor pool and a rooftop terrace. Families will appreciate the onsite laundry facilities and in-room childcare. Unwind with a drink ...
9.2/10 Wonderful! (499 reviews)
Great find in Santiago
"Great little boutique hotel conveniently located near parks, cafes, restaurants, all walking distance. Reached out to the hotel day before arrival and they arranged a ride from the airport. (If you can, give them more time!). Checking was smoothly, personnel very helpful. Got a spacious upgraded ..."

Reviewed on Aug 3, 2025

Opens in a new windowCasa Bueras Boutique Hotel
Altiplanico Bellas Artes

Altiplanico Bellas Artes

Santo Domingo 526, Santiago, Region Metropolitana
Fully refundableReserve now, pay when you stay
This hotel features a bar/lounge, free WiFi in public areas, and a fireplace in the lobby. Free buffet breakfast is served. A computer station, luggage storage, ...
9.2/10 Wonderful! (534 reviews)
"Employees were great!"

Reviewed on Aug 20, 2025

Opens in a new windowAltiplanico Bellas Artes
Matildas Hotel Boutique

Matildas Hotel Boutique

Agustinas 2149, Plaza Brasil, Santiago, Region Metropolitana
Fully refundableReserve now, pay when you stay
This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Traveling on business? Take advantage of the business center, ...
9.2/10 Wonderful! (268 reviews)
"We had a wonderful stay! Great location as well as its on a street where you can just walk straight down for as little as 15 to 20 minutes and get to some great restaurants and sights! We hope to stay here again one day!"

Reviewed on Aug 9, 2025

Opens in a new windowMatildas Hotel Boutique
Hotel Plaza San Francisco

Hotel Plaza San Francisco

Alameda 816, Santiago, Region Metropolitana
Fully refundableReserve now, pay when you stay
$185 nightly
The price is $185 total per night from Oct 2 to Oct 3
$185 total
Oct 2 - Oct 3
A full-service spa, a gym, and a restaurant are all featured at this boutique hotel. Traveling on business? Take advantage of the business center, free WiFi ...
9/10 Wonderful! (935 reviews)
Location
"Location is great for walk tours and precolumbus museum. The walls seemed a bit thin to hear neighbors (baby crying next door)"

Reviewed on Sep 15, 2025

Opens in a new windowHotel Plaza San Francisco
Lastarria Hotel & Aparts

Lastarria Hotel & Aparts

José Victorino Lastarria, 43, Santiago, Region Metropolitana
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $65 total per night from Oct 18 to Oct 19
$65 total
Oct 18 - Oct 19
This aparthotel features free WiFi in public areas, laundry facilities, and self parking. A terrace and a safe deposit box are also provided.
9/10 Wonderful! (254 reviews)
"Booked for a week stay based on good reviews and excellent price. Studio apartment was clean and perfect for our needs. Be aware there is no elevator (we were on the 3rd floor, building at 43). Make sure the front building door closes properly! The staff was very helpful and made us feel welcome. ..."

Reviewed on Jul 24, 2025

Opens in a new windowLastarria Hotel & Aparts
Luciano K Hotel

Luciano K Hotel

Merced, 84, Lastarria, Santiago, Región Metropolitana
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $110 total per night from Oct 14 to Oct 15
$110 total
Oct 14 - Oct 15
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the laundry service ...
8.8/10 Excellent! (645 reviews)
"The hotel is so sweet and amazing g design. The staff were fantastic. Really helpful and kind. Christian at the restaurant was super lovely. The restaurant food was excellent . Breakfast was great . Great location. Will stay again."

Reviewed on Sep 27, 2025

Opens in a new windowLuciano K Hotel
Hotel Vegas

Hotel Vegas

Londres 49, Santiago, Region Metropolitana
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the free WiFi in public areas, airport shuttle, and free internet ...
"This was a wonderful little boutique hotel on a walkable cobbled street. The staff was exceptional and the room was very comfortable and quiet. It was easily in walking distance to Centro and right by a subway stop. Wonderful little place to stay. Thank you!"

Reviewed on Mar 30, 2023

Opens in a new windowHotel Vegas
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5 star hotels in Downtown Santiago

The Singular Santiago

The Singular Santiago

Merced 294, Santiago, Region Metropolitana
$250 nightly
The price is $250 total per night from Oct 11 to Oct 12
$250 total
Oct 11 - Oct 12
9.4/10 Exceptional! (649 reviews)

Downtown Santiago Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Downtown Santiago luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Downtown Santiago to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Downtown Santiago will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Downtown Santiago, and plan your next opulent escape.


Downtown Santiago hotels essential information

Accommodation
865 hotels
Lowest Price
$65
Highest Price
$250
Popular hotels
The Singular Santiago, Casa Bueras Boutique Hotel, Luciano K Hotel, Altiplanico Bellas Artes, Matildas Hotel Boutique, Hotel Plaza San Francisco, Lastarria Hotel & Aparts, Hotel Vegas

Popular Luxury Stays in Downtown Santiago

Recent Downtown Santiago Hotel Reviews By Fellow Wanderers

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