Explore 10 Luxury Hotels in Downtown Santiago

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Best Luxury Hotels in Downtown Santiago

The Singular Santiago

The Singular Santiago

Merced 294 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
$239 nightly
The price is $239 total per night from Dec 24 to Dec 25
$239 total
Dec 24 - Dec 25
A full-service spa, 2 restaurants, and A 24-hour gym are all featured at this smoke-free hotel. Enjoy the seasonal outdoor pool and free perks like cooked-to-order ...
9.4/10 Exceptional! (674 reviews)
All of the above

Reviewed on Dec 8, 2025

Opens in a new windowThe Singular Santiago
Casa Bueras Boutique Hotel

Casa Bueras Boutique Hotel

Coronel Santiago Bueras 188 Santiago Region Metropolitana
$138 nightly
The price is $138 total per night from Dec 23 to Dec 24
$138 total
Dec 23 - Dec 24
This hotel features an outdoor pool and a rooftop terrace. Families will appreciate the onsite laundry facilities and in-room childcare. Unwind with a drink ...
9.2/10 Wonderful! (509 reviews)
The staff were all so incredibly nice!!! The hotel was beautiful too!!

Reviewed on Dec 2, 2025

Opens in a new windowCasa Bueras Boutique Hotel
Altiplanico Bellas Artes

Altiplanico Bellas Artes

Santo Domingo 526 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
This hotel features a bar/lounge, free WiFi in public areas, and a fireplace in the lobby. Free buffet breakfast is served. A computer station, luggage storage, ...
9.2/10 Wonderful! (553 reviews)
Beautiful hotel and room. Staff were super nice and helpful. Great location.

Reviewed on Dec 2, 2025

Opens in a new windowAltiplanico Bellas Artes
Matildas Hotel Boutique

Matildas Hotel Boutique

Agustinas 2149 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
$150 nightly
The price is $150 total per night from Dec 12 to Dec 13
$150 total
Dec 12 - Dec 13
This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Traveling on business? Take advantage of the business center, ...
9.2/10 Wonderful! (275 reviews)
Wonderful boutique hotel in heritage residence from 1912. Garden, library and honor lounge are beautifully preserved. Convenient location and access. Very helpful and very pleasant staff. One complaint only- air conditioner was intermittently noisy.

Reviewed on Nov 28, 2025

Opens in a new windowMatildas Hotel Boutique
Hotel Plaza San Francisco

Hotel Plaza San Francisco

Alameda 816 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
$157 nightly
The price is $157 total per night from Dec 11 to Dec 12
$157 total
Dec 11 - Dec 12
A full-service spa, a gym, and a restaurant are all featured at this boutique hotel. Traveling on business? Take advantage of the business center, free WiFi ...
9/10 Wonderful! (960 reviews)
The hotel staff were all extremely nice and helpful. Particularly I would like to mention reception team. When we were leaving for the airport, our Uber didnt come as it was pre - booked and they found us driver promptly who took us to the airport.

Reviewed on Dec 1, 2025

Opens in a new windowHotel Plaza San Francisco
Lastarria Hotel & Aparts

Lastarria Hotel & Aparts

José Victorino Lastarria, 43 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $63 total per night from Dec 15 to Dec 16
$63 total
Dec 15 - Dec 16
This aparthotel features free WiFi in public areas, laundry facilities, and self parking. A terrace and a safe deposit box are also provided.
9/10 Wonderful! (265 reviews)
Wonderful place. Very kind people, clean rooms.

Reviewed on Nov 28, 2025

Opens in a new windowLastarria Hotel & Aparts
Luciano K Hotel

Luciano K Hotel

Merced, 84 Santiago Región Metropolitana
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $135 total per night from Dec 24 to Dec 25
$135 total
Dec 24 - Dec 25
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the laundry service ...
8.8/10 Excellent! (681 reviews)
The hotel is located in a quiet area. There plenty of restaurants nearby and a lovely park across the street. The hotel itself is lovely, decor is really nice. The rooftop bar is great. All staff, reception, cleaners and bar staff are friendly and helpful. I really liked this hotel.

Reviewed on Dec 6, 2025

Opens in a new windowLuciano K Hotel
Hotel Vegas

Hotel Vegas

Londres 49 Santiago Region Metropolitana
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the free WiFi in public areas, airport shuttle, and free internet ...
This was a wonderful little boutique hotel on a walkable cobbled street. The staff was exceptional and the room was very comfortable and quiet. It was easily in walking distance to Centro and right by a subway stop. Wonderful little place to stay. Thank you!

Reviewed on Mar 30, 2023

Opens in a new windowHotel Vegas
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More 4 star hotels in Downtown Santiago

5 star hotels in Downtown Santiago

The Singular Santiago

The Singular Santiago

Merced 294 Santiago Region Metropolitana
$239 nightly
The price is $239 total per night from Dec 24 to Dec 25
$239 total
Dec 24 - Dec 25
9.4/10 Exceptional! (674 reviews)

Downtown Santiago Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Downtown Santiago luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Downtown Santiago to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Downtown Santiago will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Downtown Santiago, and plan your next opulent escape.


Downtown Santiago hotels essential information

Accommodation
995 hotels
Lowest Price
$63
Highest Price
$239
Popular hotels
The Singular Santiago, Casa Bueras Boutique Hotel, Luciano K Hotel, Altiplanico Bellas Artes, Matildas Hotel Boutique, Hotel Plaza San Francisco, Lastarria Hotel & Aparts, Hotel Vegas

Popular Luxury Stays in Downtown Santiago

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