Southwest Illinois Vacation Packages 2026/2026 from $555

Southwest Illinois flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

The Wildwood Hotel

$555

per person

Jan 30 - Feb 1

found 1 day ago

Roundtrip non-stop flight included

Tampa (TPA) to St. Louis (STL)

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot tub and free perks like continental breakfast and free self parking.

Ameristar Casino Resort and Spa

$679

per person

Jan 30 - Feb 1

found 1 day ago

Roundtrip non-stop flight included

Tampa (TPA) to St. Louis (STL)

This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside bar.

The Knight Center at Washington University

$574

per person

Jan 30 - Feb 1

found 1 day ago

Roundtrip non-stop flight included

Tampa (TPA) to St. Louis (STL)

A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Self parking and a coffee shop are also offered on site.

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Grand Center

$556

per person

Feb 27 - Mar 1

found 1 day ago

Roundtrip flight included

Washington (DCA) to St. Louis (STL)

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, along with free WiFi in public areas. There's a rooftop terrace on site, and a 24-hour front desk and a snack bar/deli are also provided.

Hotel Saint Louis, Autograph Collection

Downtown St. Louis

$596

per person

Jan 30 - Feb 1

found 1 day ago

Roundtrip non-stop flight included

Tampa (TPA) to St. Louis (STL)

This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. There's a bar/lounge on site, and laundry facilities and concierge services are also provided.

Top Southwest Illinois hotels deals

Drury Plaza Hotel Mt. Vernon

145 North 44th Street Mount Vernon IL

Free Cancellation

Reserve now, pay when you stay

$91 nightly

$104 total

Dec 14 - Dec 15

Total with taxes and fees

This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the 24-hour gym and free perks like buffet breakfast and free self parking.

Pool

Hot Tub

Super 8 by Wyndham O'Fallon

1100 Eastgate Dr O'Fallon IL

Free Cancellation

Reserve now, pay when you stay

$43 nightly

$49 total

Dec 14 - Dec 15

Total with taxes and fees

This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like on-the-go breakfast and free self parking.

Pool

Breakfast included

Drury Inn & Suites St. Louis Fairview Heights

12 Ludwig Dr Fairview Heights IL

Free Cancellation

Reserve now, pay when you stay

$94 nightly

$106 total

Dec 14 - Dec 15

Total with taxes and fees

This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.

Pool

Hot Tub

Quality Inn & Suites near St. Louis and I-255

1607 Pontiac Dr East St. Louis IL

Free Cancellation

Reserve now, pay when you stay

$65 nightly

$74 total

Dec 21 - Dec 22

Total with taxes and fees

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like on-the-go breakfast and free self parking.

Pool

Breakfast included

Comfort Suites Mount Vernon

404 South 44th Street Mount Vernon IL

Free Cancellation

Reserve now, pay when you stay

$109 nightly

$123 total

Dec 8 - Dec 9

Total with taxes and fees

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and free perks like buffet breakfast and free self parking.

Pool

Hot Tub

Best Western Plus Pontoon Beach

4 Regency Pkwy Granite City IL

Free Cancellation

Reserve now, pay when you stay

$85 nightly

$95 total

Dec 10 - Dec 11

Total with taxes and fees

Pool

Breakfast included

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Southern Illinois University

4.5/5(173 reviews)

Take a campus tour or just explore the area of Southern Illinois University, during your trip to Carbondale. Check out the shops and top-notch restaurants in this family-friendly area.

Ferne Clyffe Waterfall Detail
Goreville IL
#detail

Ferne Clyffe State Park

4.5/5(10 reviews)

You can take time to visit Ferne Clyffe State Park during your travels to Goreville. While you're in the area, wander around the parks.

Southern Illinois which includes autumn leaves and forests

Tunnel Hill State Trail

4/5(2 reviews)

You can take time to visit Tunnel Hill State Trail during your travels to Vienna. Amble around the area's parks or experience its museums.

Frequently asked questions

How much are vacation packages to Southwest Illinois?

Travelocity provides package deals to Southwest Illinois, including hotels and flights, starting from as low as $555. With all the cash you save, you could book some cool tours or even add some extra nights to your getaway.

Where can I get the best vacation package deals for Southwest Illinois?

Whatever your travel style, Travelocity can help you get your hands on an unbeatable Southwest Illinois package deal. The only thing you need to do is mix and match from our 400 air carriers and 1,000,000 worldwide properties.

Why should I purchase my Southwest Illinois vacation bundle with Travelocity?

From our 24/7 support to our range of exciting destinations, we're committed to giving you the most unforgettable vacation. All you have to do is click and book — our Price Match Guarantee will ensure you score the best deal.

Can I save on my Southwest Illinois car rental if I bundle it with hotels and flights?

Combining your bookings into a Southwest Illinois vacation package will save you a tidy sum. You can choose a flight and car; a flight, hotel and car; or a car and hotel. You won't find a better way to explore the greater Southwest Illinois region than with your own ride. You can also add tours and experiences to your Travelocity package.

Which airport is best for Southwest Illinois?

If the plan is to fly into Southwest Illinois, chances are you'll be arriving at Lambert-St. Louis Intl. Airport (STL) or Williamson County Regional Airport (MWA).

What is there to do in Southwest Illinois?

Southwest Illinois boasts hidden surprises around every turn, but make sure you plan a visit to both Southern Illinois University and Lake of Egypt during your stay. These attractions shouldn't be missed.