A little fog can’t diminish the drama of San Francisco’s winding streets and bay views. The spectacular scenery, plus quirky neighborhoods and access to some of the country’s most celebrated food and wine, makes this California hub a perennial favorite with travelers. Whether flagging a cable car for Fisherman’s Wharf or ferrying to Alcatraz, the setting is the highlight. But along with the never-ending vistas, there’s never a shortage of things to do next. Bridge-side beaches are a good option even when it’s chilly—which is likely, as San Francisco is the coldest major U.S. city in the summer. Luckily, the city offers plenty of museums and shopping opportunities for gray days. San Francisco restaurants are a refuge whether the day brings blue skies or rain showers. Excellent sushi places abound, eating in Chinatown can be divine, and there are a lot of Michelin stars scattered among San Fran’s streets. For a view of it all, and an excellent brunch to boot, head to the Cliff House. And if you’re not too full after dining all day and night, San Francisco is one city that has a slice of nightlife for everyone.

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