American Airlines Flight 2280 Deals & Information (2025/2026)

Wander Wisely with exceptional service, 24/7 supportOpens in a new window

Feel at ease with free flight cancellations within 24 hours of booking

Change your flight without a fee on select flights

American Airlines Flight 2280 Route Deals From $145

The cheapest prices found with in the last 7 days for return flights were $305 and $145 for one-way flights to Charlotte-Douglas Intl. for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, Aug 25 - Wed, Aug 27
CHS
Charleston Intl.
CLT
Charlotte-Douglas Intl.
$305 Roundtrip, found 1 day ago
$305
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Aug 25 from Charleston Intl. to Charlotte-Douglas Intl., returning Wed, Aug 27, priced at $305 found 1 day ago
Mon, Aug 25 - Wed, Aug 27
CHS
Charleston Intl.
CLT
Charlotte-Douglas Intl.
$322 Roundtrip, found 1 day ago
$322
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Aug 25 from Charleston Intl. to Charlotte-Douglas Intl., returning Wed, Aug 27, priced at $322 found 1 day ago
Fri, Sep 5 - Mon, Sep 8
CHS
Charleston Intl.
CLT
Charlotte-Douglas Intl.
$339 Roundtrip, found 2 days ago
$339
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Sep 5 from Charleston Intl. to Charlotte-Douglas Intl., returning Mon, Sep 8, priced at $339 found 2 days ago
Fri, Sep 5 - Mon, Sep 8
CHS
Charleston Intl.
CLT
Charlotte-Douglas Intl.
$342 Roundtrip, found 2 days ago
$342
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Sep 5 from Charleston Intl. to Charlotte-Douglas Intl., returning Mon, Sep 8, priced at $342 found 2 days ago
Fri, Sep 5 - Mon, Sep 8
CHS
Charleston Intl.
CLT
Charlotte-Douglas Intl.
$344 Roundtrip, found 2 days ago
$344
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Sep 5 from Charleston Intl. to Charlotte-Douglas Intl., returning Mon, Sep 8, priced at $344 found 2 days ago
Fri, Sep 5 - Mon, Sep 8
CHS
Charleston Intl.
CLT
Charlotte-Douglas Intl.
$351 Roundtrip, found 2 days ago
$351
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Sep 5 from Charleston Intl. to Charlotte-Douglas Intl., returning Mon, Sep 8, priced at $351 found 2 days ago
Mon, Aug 25 - Wed, Aug 27
CHS
Charleston Intl.
CLT
Charlotte-Douglas Intl.
$354 Roundtrip, found 1 day ago
$354
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Aug 25 from Charleston Intl. to Charlotte-Douglas Intl., returning Wed, Aug 27, priced at $354 found 1 day ago
Mon, Aug 25 - Wed, Aug 27
CHS
Charleston Intl.
CLT
Charlotte-Douglas Intl.
$359 Roundtrip, found 1 day ago
$359
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Aug 25 from Charleston Intl. to Charlotte-Douglas Intl., returning Wed, Aug 27, priced at $359 found 1 day ago
Mon, Aug 25 - Wed, Aug 27
CHS
Charleston Intl.
CLT
Charlotte-Douglas Intl.
$365 Roundtrip, found 1 day ago
$365
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Aug 25 from Charleston Intl. to Charlotte-Douglas Intl., returning Wed, Aug 27, priced at $365 found 1 day ago
Mon, Aug 25 - Wed, Aug 27
CHS
Charleston Intl.
CLT
Charlotte-Douglas Intl.
$366 Roundtrip, found 1 day ago
$366
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Aug 25 from Charleston Intl. to Charlotte-Douglas Intl., returning Wed, Aug 27, priced at $366 found 1 day ago

Frequently asked questions

What route does flight number AA2280 take?
AA2280 takes multiple routes. The most popular is between Guadalajara Intl. Airport and Dallas-Fort Worth Intl. Airport (DFW), which flies direct. This service generally takes 2 hours and 41 minutes. That said, there are likely to be other flights with this number that are multi-stop.
What terminal does AA2280 fly out of?
Terminal 1 is where you'll most likely jet off from if you're booked on a flight out of Don Miguel Hidalgo y Costilla Intl. Airport (GDL). Don Miguel Hidalgo y Costilla Intl. Airport (GDL) to Dallas, TX Airport (DFW-Dallas-Fort Worth Intl.) is the most frequently traveled route for flight number AA2280.
What kind of plane is on flight number AA2280?
It's possible you'll be on a Boeing 737-800 if you've booked a seat from GDL to DFW Airport, one of a few routes used for flight AA2280.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA2280 flight with Travelocity, please visit our Customer Service Portal.