
$728 Cheap American Airlines flights from Panama City to Madrid (PTY to MAD)
Find The Best Day To Fly from Panama City to Madrid
Amazing American Airlines PTY to MAD Flight Deals
The cheapest flights to Adolfo Suárez Madrid-Barajas found within the past 7 days were $1,139 round trip and $728 one way. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Discover our best American Airlines flight from Panama City PTY to Madrid MAD
To find the best deals on flights to Panama City from Madrid with American Airlines, just enter your travel dates, filter by American Airlines, and hit search. You’ll find flights to choose from and can sort by price, flight duration, and arrival or departure time.
Return flights from Panama City PTY to Madrid MAD with American Airlines
If you’re planning a round trip, booking return flights with American Airlines is usually the most cost-effective option. With airfares ranging from $1,139 to $1,139, it’s easy to find a flight that suits your budget. Prices and availability subject to change. Additional terms may apply.
Book one-way American Airlines flights from Panama City PTY to Madrid MAD
A one-way ticket gives you much greater flexibility—allowing you to choose your return date, destination, and time whenever you’re ready. By booking in advance you can find great deals on one-way tickets too. Right now, a one-way American Airlines flight from Panama City to Madrid costs from $728. Prices and availability subject to change. Additional terms may apply.
The easy way to find cheap flights to Madrid MAD from Panama City PTY with American Airlines
To find a cheap American Airlines flight from Panama City PTY to Madrid MAD, sort your search results by price or filter by budget. Thanks to Travelocity’s Price Match Promise, if you find a better airfare deal anywhere else within 24 hours, we’ll credit or refund the difference.
How to find our best airfare deals on American Airlines flights from Panama City PTY to Madrid MAD
If you’re looking for cheap flights, it helps to be flexible when it comes to your travel dates. You’ll usually find lower cost tickets when you travel during quieter months such as October, or if you book a flight with a stopover.
Find nonstop flights from Panama City PTY to Madrid MAD with American Airlines
If you’re keen to be on Madrid soil fast, don’t waste time with a stopover—filter your search results to show direct American Airlines flights only. The journey takes around hour(s) min(s) – so you’ll be there before you know it.
Flexible airline tickets for American Airlines flights from Panama City PTY to Madrid MAD
Make sure you’re not out of pocket if plans change by choosing a flexible ticket with penalty-free amendment and cancellation options. Use our ‘no change fee’ filter to see which flights have this option.
There are a lot of reasons to book your flights to Madrid MAD from Panama City PTY with American Airlines on Travelocity
At Travelocity our vast and up-to-the-minute inventory puts all of our best flight deals in one place. So, whether you’re traveling on business or jetting off with friends and family, you can trust Travelocity to get you there.
Airport code | Country | Airport name | Number of flights |
---|---|---|---|
DFW | USA | Dallas-Fort Worth Intl. | 599 |
CLT | USA | Charlotte-Douglas Intl. | 536 |
ORD | USA | O'Hare Intl. | 317 |
PHL | USA | Philadelphia Intl. | 247 |
MIA | USA | Miami Intl. | 193 |
DCA | USA | Ronald Reagan Washington National | 152 |
PHX | USA | Sky Harbor Intl. | 141 |
LAX | USA | Los Angeles Intl. | 81 |
LGA | USA | LaGuardia | 72 |
BOS | USA | Logan Intl. | 57 |
Travelers ❤️ these 🏨 after their flight to Madrid

Senator Barajas Hotel
Reviewed on Jul 28, 2025

Hotel Madrid Alameda Aeropuerto, Affiliated by Meliá
Reviewed on Jul 30, 2025

Zleep Hotel Madrid Airport
Reviewed on Jul 29, 2025
Popular American Airlines Flight Routes from PTY
Top American Airlines Flight Routes from MAD
Top Flights for American Airlines originating from PTY
Domestic
- New York to Miami (JFK - MIA)
- New York to Santiago (JFK - STI)
- Newark Liberty Intl. Airport to Santiago (EWR - STI)
- Philadelphia to Orlando (PHL - MCO)
- New York to Orlando (JFK - MCO)
- New York to Mexico City (JFK - MEX)
- Chicago to Las Vegas (ORD - LAS)
- Philadelphia to San Juan (PHL - SJU)
- Chicago to Mexico City (ORD - MEX)
- San Juan to Orlando (SJU - MCO)
International
- Chicago to Mexico City (ORD - MEX)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- Los Angeles to San Salvador (LAX - SAL)
- Atlanta to Las Vegas (ATL - LAS)
- New York to Montego Bay (JFK - MBJ)
- Chicago to Mexico City (ORD - MEX)
- Newark Liberty Intl. Airport to San Juan (EWR - SJU)
- Philadelphia to San Juan (PHL - SJU)
- New York to Mexico City (JFK - MEX)
- New York to Orlando (LGA - MCO)
Most Popular
- Panama City to Contadora Island (PTY - OTD)
- Hawaiian Airlines Santa Ana (SNA) to Honolulu (HNL) flights
- Flights to Las Vegas
- White Plains to Chattanooga (HPN - CHA)
- JetBlue Airways Orlando (MCO) to Portland (PWM) flights
- Qantas Airways Los Angeles (LAX) to Melbourne (MEL) flights
- United New York (JFK) to Paris (CDG) flights
- Seattle to Oklahoma City (SEA - OKC)
- American Airlines Tampa (TPA) to Los Angeles (ONT) flights
- Detroit to San Antonio (DTW - SAT)
- Delta Salt Lake City (SLC) to San Jose (SJC) flights
- Flights to Ohio
- West Palm Beach to Tucson (PBI - TUS)
- KLM Dar es Salaam (DAR) to Toronto (YYZ) flights
- American Airlines Miami (MIA) to Des Moines (DSM) flights
- Delta Atlanta (ATL) to Laredo (LRD) flights
- American Airlines Dallas (DFW) to Oakland (OAK) flights
- Delta Atlanta (ATL) to Fort Lauderdale (FLL) flights
- New York to Madrid (JFK - MAD)
- Lincoln to Rapid City (LNK - RAP)