
$324 Cheap American Airlines flights from Moline to Columbia (MLI to CAE)
Find The Best Day To Fly from Moline to Columbia
Amazing American Airlines MLI to CAE Flight Deals
The cheapest flights to Columbia Metropolitan found within the past 7 days were $347 round trip and $324 one way. Prices and availability subject to change. Additional terms may apply.
MLI
Moline
CAE
Columbia
$347 Roundtrip, found 22 hours ago
$347
Roundtrip
found 22 hours ago
MLI
Moline
CAE
Columbia
$352 Roundtrip, found 22 hours ago
$352
Roundtrip
found 22 hours ago
MLI
Moline
CAE
Columbia
$369 Roundtrip, found 22 hours ago
$369
Roundtrip
found 22 hours ago
MLI
Moline
CAE
Columbia
$374 Roundtrip, found 22 hours ago
$374
Roundtrip
found 22 hours ago
MLI
Moline
CAE
Columbia
$377 Roundtrip, found 22 hours ago
$377
Roundtrip
found 22 hours ago
MLI
Moline
CAE
Columbia
$396 Roundtrip, found 22 hours ago
$396
Roundtrip
found 22 hours ago
CAE From MLI Economy Coach Packages on Similar Airlines
Price found within the past 48 hours. Click for updated prices.



Don't see what you're looking for?
See all available trips from Quad City Intl. to Columbia Metropolitan
View all tripsAirport code | Country | Airport name | Number of flights |
---|---|---|---|
DFW | USA | Dallas-Fort Worth Intl. | 599 |
CLT | USA | Charlotte-Douglas Intl. | 536 |
ORD | USA | O'Hare Intl. | 317 |
PHL | USA | Philadelphia Intl. | 247 |
MIA | USA | Miami Intl. | 193 |
DCA | USA | Ronald Reagan Washington National | 152 |
PHX | USA | Sky Harbor Intl. | 141 |
LAX | USA | Los Angeles Intl. | 81 |
LGA | USA | LaGuardia | 72 |
BOS | USA | Logan Intl. | 57 |
Travelers ❤️ these 🏨 after their flight to Columbia

Country Inn & Suites by Radisson, Columbia Airport, SC
2245 Airport Blvd, Cayce, SC
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free ...
8.2/10 Very Good! (1,006 reviews)
"This property is always 1st on my list to visit when I’m in the CAE area. It is very well maintained."
Reviewed on Jul 19, 2025

Motel 6 West Columbia, SC - Airport
650 Cherokee Lane, West Columbia, SC
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A picnic area, laundry facilities, and barbecue grills are also on ...
7.6/10 Good! (326 reviews)
"Great rooms this is my go to for the area after one stay."
Reviewed on Jul 12, 2025

Quality Inn Columbia Airport
2516 Augusta Rd, West Columbia, SC
A seasonal outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like continental breakfast and ...
6.6/10 (946 reviews)
"Very nice stay. Always comfortable here."
Reviewed on Jul 13, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular American Airlines Flight Routes from MLI
Top American Airlines Flight Routes from CAE
- American Airlines CAE to DFW
- American Airlines CAE to MSY
- American Airlines CAE to PIT
- American Airlines CAE to LGA
- American Airlines CAE to SEA
- American Airlines CAE to MIA
- American Airlines CAE to PHL
- American Airlines CAE to DCA
- American Airlines CAE to DEN
- American Airlines CAE to CVG
- American Airlines CAE to ONT
Top Flights for American Airlines originating from MLI
Domestic
- New York to Orlando (LGA - MCO)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- Philadelphia to Orlando (PHL - MCO)
- New York to Miami (LGA - MIA)
- Chicago to Las Vegas (ORD - LAS)
- Newark Liberty Intl. Airport to Fort Lauderdale (EWR - FLL)
- New York to San Juan (JFK - SJU)
- Newark Liberty Intl. Airport to Miami (EWR - MIA)
- Orlando to San Juan (MCO - SJU)
- New York to Santiago (JFK - STI)
International
- New York to Montego Bay (JFK - MBJ)
- Philadelphia to San Juan (PHL - SJU)
- Philadelphia to San Juan (PHL - SJU)
- Chicago to San Juan (ORD - SJU)
- New York to San Juan (JFK - SJU)
- Orlando to San Juan (MCO - SJU)
- Chicago to Mexico City (ORD - MEX)
- Philadelphia to Orlando (PHL - MCO)
- New York to Santiago (JFK - STI)
- Chicago to Las Vegas (ORD - LAS)
Most Popular
Flights
- Phoenix to Chicago (PHX - ORD)
- Chicago to Denver (ORD - DEN)
- Los Angeles to Chicago (LAX - ORD)
- Chicago to Las Vegas (ORD - LAS)
- Philadelphia to Chicago (PHL - ORD)
- Chicago to Miami (ORD - MIA)
- Chicago to Fort Myers (ORD - RSW)
- Chicago to Washington (ORD - DCA)
- New York to Chicago (JFK - ORD)
- Chicago to Orlando (ORD - MCO)
- Chicago to Tampa (ORD - TPA)
- Chicago to Mexico City (ORD - MEX)
- Chicago to Phoenix (ORD - PHX)
- Chicago to Dallas (ORD - DFW)
- Chicago to Atlanta (ORD - ATL)
- Chicago to Nashville (ORD - BNA)
- New York to Charleston (JFK - CHS)
- Chicago to Philadelphia (ORD - PHL)
- Chicago to San Francisco (ORD - SFO)
- Tampa to Chicago (TPA - ORD)
- Dallas to Chicago (DFW - ORD)
- Chicago to Fort Lauderdale (ORD - FLL)
- Chicago to Boston (ORD - BOS)
- Orlando to Chicago (MCO - ORD)
- JetBlue Airways Boston (BOS) to North Charleston (CHS) flights
- San Francisco to Chicago (SFO - ORD)
- Raleigh to Chicago (RDU - ORD)
- Denver to Chicago (DEN - ORD)
- Chicago to Los Angeles (ORD - LAX)
- Chicago to Cancun (ORD - CUN)