
$156 Cheap American Airlines flights from Louisville to San Diego (SDF to SAN)
Find The Best Day To Fly from Louisville to San Diego
Amazing American Airlines SDF to SAN Flight Deals
The cheapest flights to San Diego Intl. found within the past 7 days were $325 round trip and $156 one way. Prices and availability subject to change. Additional terms may apply.
SAN From SDF Economy Coach Packages on Similar Airlines



Frequently asked questions
Discover our best American Airlines flight from Louisville SDF to San Diego SAN
To find the best deals on flights to Louisville from San Diego with American Airlines, just enter your travel dates, filter by American Airlines, and hit search. You’ll find flights to choose from and can sort by price, flight duration, and arrival or departure time.
Return flights from Louisville SDF to San Diego SAN with American Airlines
If you’re planning a round trip, booking return flights with American Airlines is usually the most cost-effective option. With airfares ranging from $325 to $382, it’s easy to find a flight that suits your budget. Prices and availability subject to change. Additional terms may apply.
Book one-way American Airlines flights from Louisville SDF to San Diego SAN
A one-way ticket gives you much greater flexibility—allowing you to choose your return date, destination, and time whenever you’re ready. By booking in advance you can find great deals on one-way tickets too. Right now, a one-way American Airlines flight from Louisville to San Diego costs from $156. Prices and availability subject to change. Additional terms may apply.
The easy way to find cheap flights to San Diego SAN from Louisville SDF with American Airlines
To find a cheap American Airlines flight from Louisville SDF to San Diego SAN, sort your search results by price or filter by budget. Thanks to Travelocity’s Price Match Promise, if you find a better airfare deal anywhere else within 24 hours, we’ll credit or refund the difference.
How to find our best airfare deals on American Airlines flights from Louisville SDF to San Diego SAN
If you’re looking for cheap flights, it helps to be flexible when it comes to your travel dates. You’ll usually find lower cost tickets when you travel during quieter months such as October, or if you book a flight with a stopover.
Find nonstop flights from Louisville SDF to San Diego SAN with American Airlines
If you’re keen to be on San Diego soil fast, don’t waste time with a stopover—filter your search results to show direct American Airlines flights only. The journey takes around hour(s) min(s) – so you’ll be there before you know it.
Flexible airline tickets for American Airlines flights from Louisville SDF to San Diego SAN
Make sure you’re not out of pocket if plans change by choosing a flexible ticket with penalty-free amendment and cancellation options. Use our ‘no change fee’ filter to see which flights have this option.
There are a lot of reasons to book your flights to San Diego SAN from Louisville SDF with American Airlines on Travelocity
At Travelocity our vast and up-to-the-minute inventory puts all of our best flight deals in one place. So, whether you’re traveling on business or jetting off with friends and family, you can trust Travelocity to get you there.
Airport code | Country | Airport name | Number of flights |
---|---|---|---|
DFW | USA | Dallas-Fort Worth Intl. | 599 |
CLT | USA | Charlotte-Douglas Intl. | 536 |
ORD | USA | O'Hare Intl. | 317 |
PHL | USA | Philadelphia Intl. | 247 |
MIA | USA | Miami Intl. | 193 |
DCA | USA | Ronald Reagan Washington National | 152 |
PHX | USA | Sky Harbor Intl. | 141 |
LAX | USA | Los Angeles Intl. | 81 |
LGA | USA | LaGuardia | 72 |
BOS | USA | Logan Intl. | 57 |
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Reviewed on Jun 16, 2025

Reviewed on Jun 16, 2025

Reviewed on Jun 16, 2025
Popular American Airlines Flight Routes from SDF
Top American Airlines Flight Routes from SAN
- American Airlines SAN to LGA
- American Airlines SAN to HND
- American Airlines SAN to BOS
- American Airlines SAN to DEN
- American Airlines SAN to SFO
- American Airlines SAN to LAS
- American Airlines SAN to SEA
- American Airlines SAN to SGF
- American Airlines SAN to HNL
- American Airlines SAN to IAD
- American Airlines SAN to ORD
- American Airlines SAN to MCO
Top Flights for American Airlines originating from SDF
Domestic
- Newark Liberty Intl. Airport to Santiago (EWR - STI)
- Orlando to San Juan (MCO - SJU)
- New York to Orlando (JFK - MCO)
- Newark Liberty Intl. Airport to Santo Domingo (EWR - SDQ)
- Chicago to San Juan (ORD - SJU)
- Newark Liberty Intl. Airport to Las Vegas (EWR - LAS)
- Philadelphia to Orlando (PHL - MCO)
- San Juan to Orlando (SJU - MCO)
- Los Angeles to Honolulu (LAX - HNL)
- New York to Montego Bay (JFK - MBJ)
International
- Chicago to Las Vegas (ORD - LAS)
- Philadelphia to Orlando (PHL - MCO)
- San Juan to Orlando (SJU - MCO)
- Newark Liberty Intl. Airport to Santiago (EWR - STI)
- Newark Liberty Intl. Airport to Santo Domingo (EWR - SDQ)
- Newark Liberty Intl. Airport to Santo Domingo (EWR - SDQ)
- New York to Santo Domingo (JFK - SDQ)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- Newark Liberty Intl. Airport to San Juan (EWR - SJU)
- Orlando to San Juan (MCO - SJU)