$149 Cheap American Airlines flights from Des Moines to San Francisco (DSM to SFO)

Find The Best Day To Fly from Des Moines to San Francisco

Amazing American Airlines DSM to SFO Flight Deals

The cheapest flights to San Francisco Intl. found within the past 7 days were $349 round trip and $149 one way. Prices and availability subject to change. Additional terms may apply.

Fri, Aug 15 - Thu, Aug 21
DSM
Des Moines
SFO
San Francisco
$349 Roundtrip, just found
$349
Roundtrip
just found
Select American Airlines flight, departing Fri, Aug 15 from Des Moines to San Francisco, returning Thu, Aug 21, priced at $349 just found
Thu, Aug 14 - Sun, Aug 17
DSM
Des Moines
SFO
San Francisco
$359 Roundtrip, found 4 hours ago
$359
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Thu, Aug 14 from Des Moines to San Francisco, returning Sun, Aug 17, priced at $359 found 4 hours ago

SFO From DSM Economy Coach Packages on Similar Airlines

Price found within the past 48 hours. Click for updated prices.
Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

3 out of 5
per person
Oct 9 - Oct 13
found 9 hours ago
Roundtrip non-stop flight included
Des Moines (DSM) to San Francisco (SFO)
1 Hotel San Francisco

1 Hotel San Francisco

5 out of 5
Save 100% on your flight
per person
Oct 9 - Oct 13
found 9 hours ago
Roundtrip non-stop flight included
Des Moines (DSM) to San Francisco (SFO)
The Grove Inn

The Grove Inn

3 out of 5
per person
Aug 18 - Aug 22
found 21 hours ago
Roundtrip non-stop flight included
Des Moines (DSM) to San Francisco (SFO)
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Frequently asked questions

Can I catch a flight from Des Moines Intl. Airport (DSM) to SFO right now?
For information on any current SFO quarantine requirements and travel advice, go to the Covid-19 Travel Advisor. Check before you book your flight, so you don't get caught out.
What terminal is American Airlines at Des Moines Intl. Airport (DSM)?
Once you've been given the boarding pass for your flight from Des Moines Intl. Airport (DSM) to SFO, you should be able to see exactly which terminals American Airlines flies in and out of. If not, contact your airline or do some research online for that information.
Are there American Airlines non-stop flights from DSM to SFO?
You won't find any nonstop flights with American Airlines from Des Moines Intl. Airport to San Francisco Airport. You will have at least one stopover, so use this time to wander around and stretch those legs before boarding your connecting flight.
How long is an American Airlines flight from DSM to SFO?
As it will take around 6 hours and 3 minutes for your American Airlines flight to jet from Des Moines Intl. Airport (DSM) to SFO, consider throwing some travel games in your cabin bag. You never know --- the passenger sitting next to you might relish a challenge to break up the journey.
How many direct and indirect flights does American Airlines fly from DSM to SFO?
When traveling from DSM to SFO, you'll find roughly 2 American Airlines daily flights to select from.
If I am not able to travel due to COVID-19, can I change my booking to a later date?
For more info about changing your flight to San Francisco Intl. Airport (SFO), please visit our Customer Service Portal.
What is the best day to buy a plane ticket?
This just in! Airfares offered on Thursdays tend to be the cheapest, according to flight demand on Travelocity in 2021. Tuesday and Wednesday prices are also good, but you may want to prepare your budget if booking during the weekend, as data shows that is when prices are generally at their highest.
What are the cheapest days to fly?
Frequent travelers may already know this, but earlier in the week can be the cheapest time to fly. In 2021, flights departing on a Monday were generally the cheapest of the week, whereas you may pay a premium for weekend flights when demand is usually high. On average, tickets were most expensive for Saturday departures, so if you need to fly out on a weekend, you might look for deals ahead of time.
How far in advance can you book a flight?
Trying to figure out how early you should book your flight? It's possible to start comparing international airfares on Travelocity up to 12 months in advance. However, it does depend on the carrier as not all airlines release their prices that far out. According to our 2021 flight demand trends, last minute planners can still bag a bargain with some of the cheapest fares appearing 0-2 weeks prior to their travel dates.*According to flight demand on Travelocity.com from January to December 2021. Savings are subject to change based on departure location, date and destination.
American Airlines Airports
Hop on a(n) American Airlines flight today by flying to many destinations out of these domestic and international airports:
Airport code
Country
Airport name
Number of flights
DFWUSADallas-Fort Worth Intl.599
CLTUSACharlotte-Douglas Intl.536
ORDUSAO'Hare Intl.317
PHLUSAPhiladelphia Intl.247
MIAUSAMiami Intl.193
DCAUSARonald Reagan Washington National152
PHXUSASky Harbor Intl.141
LAXUSALos Angeles Intl.81
LGAUSALaGuardia72
BOSUSALogan Intl.57

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