American Airlines Flight AA381 Deals & Information (2025/2026)

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American Airlines Flight 381 Route Deals From $177

The cheapest prices found with in the last 7 days for return flights were $347 and $177 for one-way flights to Charlotte-Douglas Intl. for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Aug 30 - Tue, Sep 2
SEA
Seattle - Tacoma Intl.
CLT
Charlotte-Douglas Intl.
$347 Roundtrip, found 3 days ago
$347
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Aug 30 from Seattle - Tacoma Intl. to Charlotte-Douglas Intl., returning Tue, Sep 2, priced at $347 found 3 days ago
Sat, Aug 30 - Tue, Sep 2
SEA
Seattle - Tacoma Intl.
CLT
Charlotte-Douglas Intl.
$441 Roundtrip, found 3 days ago
$441
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Aug 30 from Seattle - Tacoma Intl. to Charlotte-Douglas Intl., returning Tue, Sep 2, priced at $441 found 3 days ago

Frequently asked questions

What route does flight number AA381 take?
AA381 is used on a number of routes. Mostly, AA381 flies direct from LaGuardia Airport to ORD. If you have a ticket on this route, you'll be in the air for about 2 hours and 55 minutes.
How often is AA381 on time?
Not fussed on hanging around at the airport? If you're traveling with American Airlines flight number AA381 from LaGuardia Airport (LGA) to ORD, this service runs as scheduled 92% of the time. On the odd occasion it is delayed, the average wait time is only 47 minutes. Just one of a multiple reasons that this journey has a 2.95-star rating.
What terminal does AA381 fly out of?
You'll most likely take off from Terminal B if you're booked on a flight out of LaGuardia Airport. AA381 serves a number of routes, but the direct flight between New York, NY Airport (LGA-LaGuardia) and O'Hare Intl. Airport (ORD) is the most frequently traveled one.
What kind of plane is on flight number AA381?
You're likely to be cruising aboard an Airbus A319 if you've reserved a ticket on flight number AA381 from New York, NY Airport (LGA-LaGuardia) to O'Hare Airport. It's the most commonly used aircraft type on this particular route.
If I am not able to travel due to COVID-19, can I change my flight to a later date?
For more info about changing your AA381 flight with Travelocity, please visit our Customer Service Portal.