
$110 Cheap Delta flights from Chicago to Greenville (MDW to GSP)
Find The Best Day To Fly from Chicago to Greenville
Amazing Delta MDW to GSP Flight Deals
The cheapest flights to Greenville-Spartanburg Intl. found within the past 7 days were $215 round trip and $110 one way. Prices and availability subject to change. Additional terms may apply.
MDW
Chicago
GSP
Greenville
$215 Roundtrip, found 11 hours ago
$215
Roundtrip
found 11 hours ago
MDW
Chicago
GSP
Greenville
$218 Roundtrip, found 11 hours ago
$218
Roundtrip
found 11 hours ago
MDW
Chicago
GSP
Greenville
$222 Roundtrip, just found
$222
Roundtrip
just found
MDW
Chicago
GSP
Greenville
$225 Roundtrip, found 11 hours ago
$225
Roundtrip
found 11 hours ago
MDW
Chicago
GSP
Greenville
$233 Roundtrip, found 11 hours ago
$233
Roundtrip
found 11 hours ago
MDW
Chicago
GSP
Greenville
$236 Roundtrip, found 1 day ago
$236
Roundtrip
found 1 day ago
MDW
Chicago
GSP
Greenville
$243 Roundtrip, just found
$243
Roundtrip
just found
GSP From MDW Economy Coach Packages on Similar Airlines
Price found within the past 48 hours. Click for updated prices.



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View all tripsTravelers ❤️ these 🏨 after their flight to Greenville

MainStay Suites Greenville Airport
2671 Dry Pocket Rd, Greer, SC
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
7.4/10 Good! (521 reviews)
"I loved the room's layout and the full-sized fridge! I didn't realize my shower was lacking a curtain until it was too close to checkout to obtain one. Also, I left my room to obtain a luggage cart and could not re-enter. I had to walk back to the front desk to reactivate the keycard. I wish places ..."
Reviewed on Apr 28, 2025

Greenville Marriott
One Parkway E, Greenville, SC
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, express check-in, ...
8.4/10 Very Good! (554 reviews)
"Very nice"
Reviewed on Apr 3, 2025

Hampton Inn & Suites Greenville Airport, SC
128 The Parkway, Greenville, SC
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Free perks include ...
9/10 Wonderful! (880 reviews)
"Only stayed one night & got there late after a flight. Room was clean and comfortable. Next morning, front desk manager Taurin was wonderful and helpful, as well as friendly. Hot breakfast was tasty and staff managing the breakfast area were friendly and helpful."
Reviewed on Apr 28, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular Delta Flight Routes from MDW
Top Flights for Delta originating from MDW
Domestic
- Atlanta to Newark Liberty Intl. Airport (ATL - EWR)
- New York to Orlando (LGA - MCO)
- Seattle to Tokyo (SEA - HND)
- Los Angeles to San Salvador (LAX - SAL)
- Newark Liberty Intl. Airport to San Juan (EWR - SJU)
- Atlanta to Newark Liberty Intl. Airport (ATL - EWR)
- New York to Santo Domingo (JFK - SDQ)
- New York to Montego Bay (JFK - MBJ)
- New York to Orlando (LGA - MCO)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
International
- Orlando to San Juan (MCO - SJU)
- San Francisco to Tokyo (SFO - HND)
- Richmond to Lagos (RIC - LOS)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- Chicago to Las Vegas (ORD - LAS)
- New York to Santiago (JFK - STI)
- San Juan to Orlando (SJU - MCO)
- Atlanta to Newark Liberty Intl. Airport (ATL - EWR)
- New York to Santo Domingo (JFK - SDQ)
- Los Angeles to Honolulu (LAX - HNL)
Most Popular
Flights
Phoenix to Chicago (PHX - ORD)Chicago to Denver (ORD - DEN)Los Angeles to Chicago (LAX - ORD)Chicago to Las Vegas (ORD - LAS)Philadelphia to Chicago (PHL - ORD)Chicago to Miami (ORD - MIA)Chicago to Fort Myers (ORD - RSW)Chicago to Washington (ORD - DCA)New York to Chicago (JFK - ORD)Chicago to Orlando (ORD - MCO)Chicago to Tampa (ORD - TPA)Chicago to Mexico City (ORD - MEX)Chicago to Phoenix (ORD - PHX)Chicago to Dallas (ORD - DFW)Chicago to Atlanta (ORD - ATL)Chicago to Nashville (ORD - BNA)New York to Charleston (JFK - CHS)Chicago to Philadelphia (ORD - PHL)Chicago to San Francisco (ORD - SFO)Tampa to Chicago (TPA - ORD)Dallas to Chicago (DFW - ORD)Chicago to Fort Lauderdale (ORD - FLL)Chicago to Boston (ORD - BOS)Orlando to Chicago (MCO - ORD)JetBlue Airways Boston (BOS) to North Charleston (CHS) flightsSan Francisco to Chicago (SFO - ORD)Raleigh to Chicago (RDU - ORD)Denver to Chicago (DEN - ORD)Chicago to Los Angeles (ORD - LAX)Chicago to Cancun (ORD - CUN)