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Top hotels in Serrano

Fairways Inn of Naples

Fairways Inn of Naples

3 out of 5
103 Palm River Blvd Naples FL
Fully refundableReserve now, pay when you stay
$124 nightly
The price is $138 total per night from Dec 22 to Dec 23
$138 total
Dec 22 - Dec 23
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi ...
Beautiful grounds, very friendly and responsive staff. Great location.

Reviewed on Dec 17, 2025

Opens in a new windowFairways Inn of Naples
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

2.5 out of 5
1538 Cape Coral Pkwy E Cape Coral FL
Fully refundable
$113 nightly
The price is $126 total per night from Dec 21 to Dec 22
$126 total
Dec 21 - Dec 22
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Friendly and accommodating staff, great breakfast selection, nicely-maintained pool, located across the street from many good local restaurants.

Reviewed on Dec 11, 2025

Opens in a new windowHoliday Inn Express Cape Coral-Fort Myers Area by IHG
Inn on Fifth

Inn on Fifth

4 out of 5
699 5th Ave S Naples FL
Fully refundable
$358 nightly
The price is $398 total per night from Jan 5 to Jan 6
$398 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the outdoor pool and perks like a free beach shuttle. Enjoy ...
Lovely and well located!

Reviewed on Dec 12, 2025

Opens in a new windowInn on Fifth
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
$157 nightly
The price is $176 total per night from Dec 23 to Dec 24
$176 total
Dec 23 - Dec 24
Total with taxes and fees
This smoke-free hotel features 3 restaurants, 3 beach bars, and 6 bars/lounges. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Enjoy ...
Everything was great. Highly recommend.

Reviewed on Dec 11, 2025

Opens in a new windowLani Kai Beachfront Resort
Sanibel Island Beach Resort

Sanibel Island Beach Resort

3 out of 5
1231 Middle Gulf Dr Sanibel FL
$251 nightly
The price is $278 total per night from Jan 4 to Jan 5
$278 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Business travelers can take advantage of the free WiFi in public areas. Relax with a drink ...
We will give everything a excellent ,restaurant ,room, for restaurant, staff, and beach

Reviewed on Dec 10, 2025

Opens in a new windowSanibel Island Beach Resort
Naples Grande Beach Resort

Naples Grande Beach Resort

4.5 out of 5
475 Seagate Drive Naples FL
Fully refundable
$440 nightly
The price is $489 total per night from Dec 19 to Dec 20
$489 total
Dec 19 - Dec 20
Total with taxes and fees
A full-service spa, 4 restaurants, and 3 outdoor pools are all featured at this luxury resort. Enjoy beachfront dining and relax with beach cabanas and sun loungers. ...
Very nice place! Housekeeping cleans room too late in the day. Our room was finally cleaned at 5:30 in the evening, every day!

Reviewed on Dec 16, 2025

Opens in a new windowNaples Grande Beach Resort
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
$230 nightly
The price is $257 total per night from Dec 21 to Dec 22
$257 total
Dec 21 - Dec 22
Total with taxes and fees
A full-service spa, 4 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Relax with a drink at one of the 4 bars/lounges and get perks ...
The staff was amazing. It is a wonderful

Reviewed on Dec 14, 2025

Opens in a new windowMargaritaville Beach Resort Fort Myers
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

4 out of 5
17260 Harbour Pointe Dr Fort Myers FL
Fully refundableReserve now, pay when you stay
$221 nightly
The price is $247 total per night from Dec 21 to Dec 22
$247 total
Dec 21 - Dec 22
Total with taxes and fees
A full-service spa, 4 restaurants, and 3 outdoor pools are all featured at this smoke-free resort. Enjoy the 5 outdoor tennis courts and indoor pool, and unwind ...
Great view from mini suite. Only real issue is self-parking is a nightmare. If you don't mind $35 per day plus tips, use the valet parking. The quality and presentation of the buffet breakfast is not on par with the rest of the facility, which is beautiful!

Reviewed on Dec 7, 2025

Opens in a new windowMarriott Sanibel Harbour Resort & Spa
La Quinta Inn & Suites by Wyndham Naples Downtown

La Quinta Inn & Suites by Wyndham Naples Downtown

2.5 out of 5
1555 5th Ave S Naples FL
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $139 total per night from Dec 21 to Dec 22
$139 total
Dec 21 - Dec 22
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Very welcoming and helpful staff. Rooms were clean and recleaned daily even thougha sign said they'd be cleaned every 3 days. Complimentary breakfast and drinks was good. Pool area was clean and enjoyable

Reviewed on Dec 14, 2025

Opens in a new windowLa Quinta Inn & Suites by Wyndham Naples Downtown
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Serrano Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Serrano area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Serrano to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Serrano are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

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