Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Hotel near Mayo Clinic Florida in Jacksonville Beach
Choose dates to view prices
Photo gallery for Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area





Reviews
9.0 out of 10
Wonderful
Popular amenities
Explore the area

1220 Marsh Landing Pkwy, Jacksonville Beach, FL, 32250
- Place, South Beach Park and Sunshine Playground12 min walk
- Place, Marsh Landing Country Club17 min walk
- Place, Atlantic Beach2 min drive
- Airport, Jacksonville, FL (JAX-Jacksonville Intl.)41 min drive
Room options
View all photos for Room, 1 King Bed, Accessible, Bathtub (Mobility & Hearing)

Room, 1 King Bed, Accessible, Bathtub (Mobility & Hearing)
8.8 out of 10
Excellent
(25 reviews)
View all photos for Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave

Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave
9.4 out of 10
Exceptional
(122 reviews)
View all photos for Room, 1 King Bed, Accessible, Non Smoking

Room, 1 King Bed, Accessible, Non Smoking
8.8 out of 10
Excellent
(14 reviews)
View all photos for Room, Accessible, Non Smoking

Room, Accessible, Non Smoking
7.8 out of 10
Good
(7 reviews)
View all photos for 1king Study Sofabed Nosmok

1king Study Sofabed Nosmok
9.2 out of 10
Wonderful
(68 reviews)
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Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Jacksonville
- Pool
- Breakfast included
- Pet friendly
- Parking included
4.4 out of 5, Excellent, 1,000 reviews
$112 nightly
The price is $127
Mar 22 - Mar 23
Total with taxes and fees
About the neighborhood
About this property
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Similar properties

Hampton Inn Jacksonville Beach/Oceanfront
Hampton Inn Jacksonville Beach/Oceanfront
- Pool
- Hot tub
- Breakfast included
- All Inclusive
4.6 out of 5, Wonderful, 2,644 reviews
$162 nightly
The price is $184
Apr 13 - Apr 14
Total with taxes and fees
Property amenities
Room amenities
Policies
Important information
Frequently asked questions
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area Reviews
Reviews
9.0
Wonderful
9.2/10
Cleanliness
9.2/10
Staff & service
8.8/10
Amenities
8.8/10
Property conditions & facilities
Reviews
Feb 24, 2026
Stayed 1 night in Feb 2026
8/10 Good
Adam
Traveled with partner, Traveled with family
Dec 15, 2025
Liked: Cleanliness, amenities, property conditions & facilities
Adam
Stayed 1 night in Dec 2025
10/10 Excellent
Michael
Dec 15, 2025
Michael
Stayed 1 night in Dec 2025
10/10 Excellent
Keisha
Traveled with partner
Dec 12, 2025
Liked: Cleanliness, amenities, property conditions & facilities
Keisha
Stayed 2 nights in Dec 2025
10/10 Excellent
Kazuiku
Dec 11, 2025
Liked: Cleanliness
Kazuiku
Stayed 1 night in Dec 2025
2/10 Terrible
Laura
Dec 10, 2025
Laura
Stayed 1 night in Dec 2025
8/10 Good
Julianne
Traveled with family
Dec 7, 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Julianne
Stayed 2 nights in Dec 2025
10/10 Excellent
Mark
Dec 7, 2025
Mark
Stayed 2 nights in Oct 2025
10/10 Excellent
Van
Dec 5, 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Van
Stayed 3 nights in Dec 2025
8/10 Good
Wayne
Dec 3, 2025
Liked: Cleanliness, staff & service, amenities
Wayne
Stayed 2 nights in Nov 2025
10/10 Excellent
Cynthia
Dec 1, 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Cynthia
Stayed 2 nights in Nov 2025
10/10 Excellent
William J
Dec 1, 2025
William J
Stayed 1 night in Nov 2025
8/10 Good
Laura
Dec 1, 2025
Laura
Stayed 3 nights in Nov 2025
10/10 Excellent
Chad
Nov 30, 2025
Chad
Stayed 3 nights in Nov 2025
10/10 Excellent
Nick
Nov 30, 2025
Nick
Stayed 2 nights in Nov 2025
10/10 Excellent
Michael
Traveled with partner
Nov 29, 2025
Liked: Cleanliness, amenities
Michael
Stayed 3 nights in Nov 2025
10/10 Excellent
Ken
Nov 29, 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Ken
Stayed 2 nights in Nov 2025
10/10 Excellent
Susan
Nov 25, 2025
Liked: Cleanliness, staff & service, amenities
Susan
Stayed 3 nights in Nov 2025
10/10 Excellent
Tyler
Nov 21, 2025
Tyler
Stayed 2 nights in Nov 2025
10/10 Excellent
Monica
Nov 21, 2025
Monica
Stayed 1 night in Nov 2025
10/10 Excellent
Romonia
Traveled with group, Business traveler
Nov 20, 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Romonia
Stayed 2 nights in Nov 2025
10/10 Excellent
Jason, Allen
Nov 10, 2025
Jason
Stayed 2 nights in Nov 2025
10/10 Excellent
Carlos
Traveled with group, Business traveler
Nov 9, 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Carlos
Stayed 1 night in Nov 2025
10/10 Excellent
William
Traveled with family
Nov 7, 2025
Liked: Cleanliness, staff & service, room comfort
William
Stayed 3 nights in Nov 2025
2/10 Terrible
James
Business traveler, Traveled with partner
Nov 7, 2025
Disliked: Cleanliness, amenities, property conditions & facilities
James
Stayed 2 nights in Nov 2025
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