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Top hotels in Serrano

The Perry Hotel Naples

The Perry Hotel Naples

4.5 out of 5
12155 Tamiami Trail N Naples FL
Fully refundableReserve now, pay when you stay
$320 nightly
The price is $356 total per night from Mar 23 to Mar 24
$356 total
Mar 23 - Mar 24
Total with taxes and fees
A marina, 2 restaurants, and 2 outdoor pools are all featured at this smoke-free hotel. Unwind with a drink at one of the 2 poolside bars and enjoy freebies ...
Hotel was beautiful. Highly recommend.

Reviewed on Mar 6, 2026

Opens in a new windowThe Perry Hotel Naples
Great Wolf Lodge Naples

Great Wolf Lodge Naples

2.5 out of 5
3900 City Gate Blvd N. Naples FL
Fully refundableReserve now, pay when you stay
$199 nightly
The price is $221 total per night from Mar 8 to Mar 9
$221 total
Mar 8 - Mar 9
Total with taxes and fees
A water park, 4 restaurants, and 3 outdoor pools are all featured at this smoke-free hotel. There's fun for all ages with a lazy river and a bowling alley, and ...
Spacious rooms, clean, nice staff. Lots of children!

Reviewed on Mar 5, 2026

Opens in a new windowGreat Wolf Lodge Naples
Sanibel Island Beach Resort

Sanibel Island Beach Resort

3 out of 5
1231 Middle Gulf Dr Sanibel FL
$447 nightly
The price is $496 total per night from Mar 12 to Mar 13
$496 total
Mar 12 - Mar 13
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Business travelers can take advantage of the free WiFi in public areas. Relax with a drink ...
I booked a suite which wasn't cheap, only to find out it's above the office and the farthest room from the beach. The property was understaffed with one person working the Tiki Bar and one bartender in the restaurant resulting in long wait times to get a drink or food. The beach is very nice, the ...

Reviewed on Mar 5, 2026

Opens in a new windowSanibel Island Beach Resort
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
$474 nightly
The price is $529 total per night from Apr 6 to Apr 7
$529 total
Apr 6 - Apr 7
Total with taxes and fees
A full-service spa, 4 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Relax with a drink at one of the 4 bars/lounges and get perks ...
It’s all about the location, the staff and facility. Margaritaville has it all.

Reviewed on Mar 4, 2026

Opens in a new windowMargaritaville Beach Resort Fort Myers
Naples Grande Beach Resort

Naples Grande Beach Resort

4.5 out of 5
475 Seagate Drive Naples FL
$572 nightly
The price is $635 total per night from Mar 7 to Mar 8
$635 total
Mar 7 - Mar 8
Total with taxes and fees
A full-service spa, 4 restaurants, and 3 outdoor pools are all featured at this luxury resort. Enjoy beachfront dining and relax with beach cabanas and sun loungers. ...
Bathroom was very dated - not worth $800 per night.

Reviewed on Mar 6, 2026

Opens in a new windowNaples Grande Beach Resort
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd Fort Myers Beach FL
$266 nightly
The price is $297 total per night from Apr 5 to Apr 6
$297 total
Apr 5 - Apr 6
Total with taxes and fees
This smoke-free hotel features 3 restaurants, 3 beach bars, and 6 bars/lounges. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. Enjoy ...
We had a balcony directly facing the beach. It was gorgeous and the hotel was lovely, but they are still having some construction so we were woken up by the sound of a drill at 8 am.

Reviewed on Mar 5, 2026

Opens in a new windowLani Kai Beachfront Resort
Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers

3 out of 5
12600 University Dr Fort Myers FL
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $151 total per night from Apr 5 to Apr 6
$151 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
We were there for a week and all was great. Most days we ate breakfast at the hotel restaurant, sat out by the fire at night, did laundry in the clean laundry room and used the printer to print our boarding passes to fly home.

Reviewed on Mar 5, 2026

Opens in a new windowHilton Garden Inn Ft Myers
Bayfront Inn Fifth Avenue

Bayfront Inn Fifth Avenue

3.5 out of 5
1221 5th Ave S Naples FL
$279 nightly
The price is $310 total per night from Mar 31 to Apr 1
$310 total
Mar 31 - Apr 1
Total with taxes and fees
A marina and an outdoor pool are featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Convenient location. OK 3-Star hotel. Not much in the way of amenities. Biggest drawback is there are no desks in the room (or even tables in the common area).If you want to use your computer for business, you'll have to be creative.

Reviewed on Mar 5, 2026

Opens in a new windowBayfront Inn Fifth Avenue
Baymont by Wyndham Fort Myers Central

Baymont by Wyndham Fort Myers Central

2.5 out of 5
4850 S Cleveland Ave Fort Myers FL
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $95 total per night from Apr 1 to Apr 2
$95 total
Apr 1 - Apr 2
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi ...
Staff was wonderful, very friendly and attentive. Room was in very poor condition — needs a refurbish desperately, particularly the bathroom.

Reviewed on Mar 6, 2026

Opens in a new windowBaymont by Wyndham Fort Myers Central
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Serrano Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Serrano area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Serrano to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Serrano are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Serrano hotel reviews by fellow wanderers

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

5 out of 5
Posted 1 hour ago
Travelocity Verified Review
"Very clean and comfortable. Busy breakfast area, but well stocked for the crowd. "
A verified traveler stayed at Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

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